In order to better carry out meteorological service and improve service efficiency,based on Tianqing data multi-factor integration platform,using Tianqing intensive data source of big data cloud platform,daily and hou...In order to better carry out meteorological service and improve service efficiency,based on Tianqing data multi-factor integration platform,using Tianqing intensive data source of big data cloud platform,daily and hourly precipitation,temperature and wind data can be acquired,and C#language can be used to realize data analysis,text template nesting,meteorological material generation and archive management functions.The application shows that the platform can quickly complete the production of rain information within 2 min,and the material filing management has zero errors,which is superior to the traditional methods in terms of framework design and data processing material management.展开更多
Vascular injury,remodeling,as well as angiogenesis,are the leading causes of coronary or cerebrovascular disease.The blood vessel functional imbalance trends to induce atherosclerosis,hypertension,and pulmonary arteri...Vascular injury,remodeling,as well as angiogenesis,are the leading causes of coronary or cerebrovascular disease.The blood vessel functional imbalance trends to induce atherosclerosis,hypertension,and pulmonary arterial hypertension.As several genes have been identified to be dynamically regulated during vascular injury and remodeling,it is becoming widely accepted that several types of non-coding RNA,such as microRNAs(miRNAs)and long non-coding RNAs(lncRNAs),are involved in regulating the endothelial cell and vascular smooth muscle cell(VSMC)behaviors.Here,we review the progress of the extant studies on mechanistic,clinical and diagnostic implications of miRNAs and lncRNAs in vascular injury and remodeling,as well as angiogenesis,emphasizing the important roles of miRNAs and lncRNAs in vascular diseases.Furthermore,we introduce the interaction between miRNAs and lncRNAs,and highlight the mechanism through which lncRNAs are regulating the miRNA function.We envisage that continuous in-depth research of non-coding RNAs in vascular disease will have significant implications for the treatment of coronary or cerebrovascular diseases.展开更多
Soil contamination by diesel has been often reported as a result of accidental spillage,leakage and inappropriate use. Surfactant-enhanced soil flushing is a common remediation technique for soils contaminated by hydr...Soil contamination by diesel has been often reported as a result of accidental spillage,leakage and inappropriate use. Surfactant-enhanced soil flushing is a common remediation technique for soils contaminated by hydrophobic organic chemicals. In this study, soil flushing with linear alkylbenzene sulfonates（LAS, an anionic surfactant） was conducted for intact columns（15 cm in diameter and 12 cm in length） of diesel-contaminated farmland purple soil aged for one year in the field. Dynamics of colloid concentration in column outflow during flushing, diesel removal rate and resulting soil macroporosity change by flushing were analyzed. Removal rate of n-alkanes（representing the diesel） varied with the depth of the topsoil in the range of 14%–96% while the n-alkanes present at low concentrations in the subsoil were completely removed by LAS-enhanced flushing. Much higher colloid concentrations and larger colloid sizes were observed during LAS flushing in column outflow compared to water flushing. The X-ray micro-computed tomography analysis of flushed and unflushed soil cores showed that the proportion of fine macropores（30–250 μm in diameter）was reduced significantly by LAS flushing treatment. This phenomenon can be attributed to enhanced clogging of fine macropores by colloids which exhibited higher concentration due to better dispersion by LAS. It can be inferred from this study that the application of LAS-enhanced flushing technique in the purple soil region should be cautious regarding the possibility of rapid colloid-associated contaminant transport via preferential pathways in the subsurface and the clogging of water-conducting soil pores.展开更多
基金Supported by Science and Technology Development Foundation for Nanchong Key Laboratory of Severe Weather Research in Northeast Sichuan (NCQXKJ202102)
文摘In order to better carry out meteorological service and improve service efficiency,based on Tianqing data multi-factor integration platform,using Tianqing intensive data source of big data cloud platform,daily and hourly precipitation,temperature and wind data can be acquired,and C#language can be used to realize data analysis,text template nesting,meteorological material generation and archive management functions.The application shows that the platform can quickly complete the production of rain information within 2 min,and the material filing management has zero errors,which is superior to the traditional methods in terms of framework design and data processing material management.
文摘Vascular injury,remodeling,as well as angiogenesis,are the leading causes of coronary or cerebrovascular disease.The blood vessel functional imbalance trends to induce atherosclerosis,hypertension,and pulmonary arterial hypertension.As several genes have been identified to be dynamically regulated during vascular injury and remodeling,it is becoming widely accepted that several types of non-coding RNA,such as microRNAs(miRNAs)and long non-coding RNAs(lncRNAs),are involved in regulating the endothelial cell and vascular smooth muscle cell(VSMC)behaviors.Here,we review the progress of the extant studies on mechanistic,clinical and diagnostic implications of miRNAs and lncRNAs in vascular injury and remodeling,as well as angiogenesis,emphasizing the important roles of miRNAs and lncRNAs in vascular diseases.Furthermore,we introduce the interaction between miRNAs and lncRNAs,and highlight the mechanism through which lncRNAs are regulating the miRNA function.We envisage that continuous in-depth research of non-coding RNAs in vascular disease will have significant implications for the treatment of coronary or cerebrovascular diseases.
基金supported by Japan Society for the Promotion of Science(RONPAKU Program,No.CAS-11313)the National Key Research and Development Plan of China(No.2016YFD0800203)the National Natural Science Foundation of China(Nos.21307152 and 41471268)
文摘Soil contamination by diesel has been often reported as a result of accidental spillage,leakage and inappropriate use. Surfactant-enhanced soil flushing is a common remediation technique for soils contaminated by hydrophobic organic chemicals. In this study, soil flushing with linear alkylbenzene sulfonates（LAS, an anionic surfactant） was conducted for intact columns（15 cm in diameter and 12 cm in length） of diesel-contaminated farmland purple soil aged for one year in the field. Dynamics of colloid concentration in column outflow during flushing, diesel removal rate and resulting soil macroporosity change by flushing were analyzed. Removal rate of n-alkanes（representing the diesel） varied with the depth of the topsoil in the range of 14%–96% while the n-alkanes present at low concentrations in the subsoil were completely removed by LAS-enhanced flushing. Much higher colloid concentrations and larger colloid sizes were observed during LAS flushing in column outflow compared to water flushing. The X-ray micro-computed tomography analysis of flushed and unflushed soil cores showed that the proportion of fine macropores（30–250 μm in diameter）was reduced significantly by LAS flushing treatment. This phenomenon can be attributed to enhanced clogging of fine macropores by colloids which exhibited higher concentration due to better dispersion by LAS. It can be inferred from this study that the application of LAS-enhanced flushing technique in the purple soil region should be cautious regarding the possibility of rapid colloid-associated contaminant transport via preferential pathways in the subsurface and the clogging of water-conducting soil pores.
