Dawei was in intensive care unit on a ventilator.He was declared brain death after a traffic accident.At visiting time,his younger brother Dayong told me their final decision to give up the subsequent treatment.“We ...Dawei was in intensive care unit on a ventilator.He was declared brain death after a traffic accident.At visiting time,his younger brother Dayong told me their final decision to give up the subsequent treatment.“We don’t have enough money and medical insurance,we can’t afford further treatment”,he said.展开更多
AIM:To evaluate the clinical significance of checking episcleral venous fluid wave(EVFW)during gonioscopyassisted transluminal trabeculotomy(GATT)in patients with open angle glaucoma(OAG).METHODS:This retrospective ca...AIM:To evaluate the clinical significance of checking episcleral venous fluid wave(EVFW)during gonioscopyassisted transluminal trabeculotomy(GATT)in patients with open angle glaucoma(OAG).METHODS:This retrospective case series study comprised 30 patients(45 eyes)with OAG underwent GATT.The location and extent of EVFW were examined and graded after intraoperative compression flushing of the anterior chamber angle during the operation.Patients were followed up for 1y.A complete success for surgery is defined as a postoperative intraocular pressure(IOP)<18 mm Hg without any anti-glaucoma medication.IOP<18 mm Hg with less than two anti-glaucoma medications is defined as qualified success,while the control of IOP requiring three anti-glaucoma medications is considered as unsuccess.RESULTS:The mean IOP was 35.38±7.16 mm Hg before surgery and 15.52±4.22 mm Hg 1y after surgery(P<0.01).The average number of anti-glaucoma medication was 2.8±1.2(2-4)preoperation and 0.6±1.3(0-3)1y postoperation(P<0.01).The success rate of the operation was 93.33%.Complete success rate was 66.67%,qualified success rate was 26.67%,and 6.66%of unsuccessful cases required reoperation.EVFW of all cases was grade 2-4,and the percentages of grade 2,3 and 4 were 33.33%,40.0%and 26.67%,respectively.The distribution and percentage of EVFW were inferior(36%),nasal(28%),superior(20%),and temporal(16%).The EVFW grade of complete success patients was 3.4±0.6(3-4),and that of qualified success patients was 2.6±1.0(2-4).The larger the range of EVFW,the lower the IOP,and the better the IOP reduction effect.CONCLUSION:During GATT surgery,pressurized irrigation of anterior chamber to check EVFW can reduce the outflow resistance of aqueous humor and increase the effect of postoperative IOP.The range of EVFW is negatively correlated with postoperative IOP.Therefore,EVFW may be a valuable prognostic indicator for the success of GATT surgery.展开更多
Objective The popularization of gastroenteroscopy and the introduction of comfortable medical care have further promoted the growth of people's demand,especially the demand for painless endoscopy.This cross-sectio...Objective The popularization of gastroenteroscopy and the introduction of comfortable medical care have further promoted the growth of people's demand,especially the demand for painless endoscopy.This cross-sectional study aims to investigate the current situation and change in county people's demand for endoscopy to promote the development of endoscopy centers in county hospitals in southeast China.Methods From October to December 2021,patients and their family members who came to the Gastroenterology Department in Suichang County People's Hospital of Zhejiang Province were randomly selected to complete the questionnaire.A total of 838 valid questionnaires were collected.Additionally,the original software data of the Endoscopy Center were sampled and retrieved(from October to December every year from 2018 to 2021)for statistical analysis of real-world data.Those who would choose painless endoscopy the next time in the valid questionnaires were included in the painless endoscopy group,while those who would choose ordinary endoscopy the next time were included in the ordinary endoscopy group.Results The stepwise forward binary logistic regression model analysis showed that,patients with“secondhand smoke exposure”were more willing to choose painless endoscopy(OR=1.459,95%CI:1.050-2.028,p=0.025).However,patients with an education level of“primary and below”and“junior high school”,and patients who are suffering from“currently experiencing abdominal distension”,were more willing to choose ordinary endoscopy(OR=0.270,95%CI:0.149-0.488,p<0.001;OR=0.528,95%CI:0.330-0.845,p=0.008;OR=0.536,95%CI:0.334-0.861,p=0.010).Patients with previous experience in painless endoscopy tended to choose painless endoscopy the next time,while patients with previous experience in ordinary endoscopy tended to choose ordinary endoscopy the next time(χ^(2)=140.97,p<0.001).From 2018 to 2021,the proportion of painless endoscopy has increased yearly(p<0.001).Most patients indicated that they would“regularly review gastroenteroscopy”(477/838,56.9%).Conclusions With Suichang County of Zhejiang Province as the representative,the demand for painless endoscopy for people's gastrointestinal cancer detection in southeast China has been increasing yearly.The development of endoscopy centers in county-level hospitals can basically meet the demand growth.Meanwhile,advanced concepts such as comfortable medical care and regular follow-up are gradually popularized at the grassroots level in southeast China.展开更多
The diseases of sweet cherry caused by viruses and viroids have occurred in the main cherry producing areas of China and are increasing year by year, which has become an important factor affecting the yield and qualit...The diseases of sweet cherry caused by viruses and viroids have occurred in the main cherry producing areas of China and are increasing year by year, which has become an important factor affecting the yield and quality of sweet cherry. For this reason, this paper elaborated the prevention and countermeasures of virus diseases from six aspects, including soil treatment, cultivation of disease-free seedlings, prevention of disease and pest damage, reasonable pruning, water management, and treatment of virus diseases, in order to provide technical guidance for the disease resistance, high quality and high yield of facility cherry, as well as information reference for the further improvement of the technical system of virus disease prevention and cultivation of facility cherry.展开更多
[Objective] The aim was to study the immobilization of laccase from Canoderma lucidum in three different sol-gel systems to find out the optimum ma- terials for laccase immobilization. [ Method ] Laccase from G. lucid...[Objective] The aim was to study the immobilization of laccase from Canoderma lucidum in three different sol-gel systems to find out the optimum ma- terials for laccase immobilization. [ Method ] Laccase from G. lucidum LYL 263 was immobilized in sodium alginate-gelatin, sodium alginate-chitosan and sodium alginate-gelatin-chitosan sol-gel systems, respectively; and the laccase activity was preliminarily analyzed. [ Result] The activity of laccase immobilized in sodium alginate-gelatin-chitosan was 2.14 folds and 2.75 folds respectively, compared to sodium alginate-gelatin and sodium alginate-chitosan; and this optimum system contained sodium alginate 2.0% , gelatin 1.0%, chitosan 0.3% and calcium chloride 56%. Benzoic acid was firstly used to embed immobilized laccase in this study, and single-factor experiments revealed that the activity of laccase could be effectively improved by suitable content of benzoic acid. The optimal conditions for laccase immobilization in the system were be^oie acid 2 retool/L, glutaraldehyde 0.32%, cross-linking reaction time 50 rain and enzyme concentration 10.0% ; and then the activity of the immobilized enzyme reached 635.7 U/g with these conditions. The thermal stability of the immobilized laccase was higher than free lac- case, and the activity of immobilized enzyme treated by freeze-drying was 1.59 folds compared to the non-freeze-dried, but the freeze-dried immobilized laccase had poor operational stability. [ Conclusion] The compositions of the material had significant influence on laccase immobilization and this study will provide reference to select materials for immobilization of laccase from G. lacidum LYL 263.展开更多
The photonic crystal structure has attracted much attention due to its ability to confine light.In this paper,we present our study on an improved Smith-Purcell radiation from a simple metal photonic crystal excited by...The photonic crystal structure has attracted much attention due to its ability to confine light.In this paper,we present our study on an improved Smith-Purcell radiation from a simple metal photonic crystal excited by moving electrons.Different from the wide-band Smith-Purcell radiation from a single metal grating,the results show that the injected electrons could induce more dipole oscillations inside the multi-grating structure,and it leads to the enhancement of the radiation intensity.In addition,there are strong resonances in metal multi-grating structure,and the resonance characteristics may narrow the radiation band,which leads to a radiation with an obvious peak in the spectrum.Therefore,the multi-grating structure has the ability to enhance the radiation intensity and shape the radiation frequency band.By optimizing the structure parameters,coherent and tunable Smith-Purcell radiation can be realized,and it provides a potential way to develop band-controllable light or THz radiation source.展开更多
目的探讨疫情期间正念干预对护理本科生心理弹性及职业认同感的影响及其机制,为提升护理本科生心理健康状况和职业认同感提供有力证据。方法2021年4月25—30日从北京市某高校完成预调查的研究对象中随机选取108名护理学生,其中有52人作...目的探讨疫情期间正念干预对护理本科生心理弹性及职业认同感的影响及其机制,为提升护理本科生心理健康状况和职业认同感提供有力证据。方法2021年4月25—30日从北京市某高校完成预调查的研究对象中随机选取108名护理学生,其中有52人作为干预组成员进行线上线下相结合的正念干预,56人作为对照组成员进行空白对照,分别利用心理弹性量表(Resilience Style Questionnaire,RSQ)、护生职业认同量表(Professional Identity for Nurse Students Questionnaire,PINSQ)评估两组成员在干预前、干预后1周、干预后3个月后(随访时)的心理弹性及职业认同感水平。利用SAS 9.4软件,采用广义估计方程评价干预效果,采用Process程序检验心理弹性的中介效应。结果干预后,干预组心理弹性高于对照组(P<0.05);随访时,干预组和对照组的心理弹性差异无统计学意义(P>0.05)。干预组学生在干预后和随访时心理弹性相比干预前均有所提高(P<0.05),随访时和干预后相比,心理弹性有所下降(P<0.05);对照组各个时间点的心理弹性水平无变化(P>0.05)。干预后,干预组职业认同感得分高于对照组(P<0.05);随访时,干预组的职业认同感高于对照组(P<0.01)。干预组职业认同感在各时间点的提升均具有统计学意义(P<0.05);对照组各个时间点的职业认同感水平差异无统计学意义(P>0.05)。正念干预可通过影响心理弹性水平进而影响职业认同感,心理弹性在其中的中介效应占比为23.67%。结论正念干预可有效提升疫情期间护理本科生的心理弹性和职业认同感水平,可为后续的心理干预和研究提供依据。展开更多
基金supported by grants from the Zhejiang Natural Science Foundation(LQ20H030005)the Zhejiang Health Technology Project(2019RC153 and 2020KY126)。
文摘Dawei was in intensive care unit on a ventilator.He was declared brain death after a traffic accident.At visiting time,his younger brother Dayong told me their final decision to give up the subsequent treatment.“We don’t have enough money and medical insurance,we can’t afford further treatment”,he said.
基金Supported by Sichuan Science and Technology Program(No.2021YFS0214).
文摘AIM:To evaluate the clinical significance of checking episcleral venous fluid wave(EVFW)during gonioscopyassisted transluminal trabeculotomy(GATT)in patients with open angle glaucoma(OAG).METHODS:This retrospective case series study comprised 30 patients(45 eyes)with OAG underwent GATT.The location and extent of EVFW were examined and graded after intraoperative compression flushing of the anterior chamber angle during the operation.Patients were followed up for 1y.A complete success for surgery is defined as a postoperative intraocular pressure(IOP)<18 mm Hg without any anti-glaucoma medication.IOP<18 mm Hg with less than two anti-glaucoma medications is defined as qualified success,while the control of IOP requiring three anti-glaucoma medications is considered as unsuccess.RESULTS:The mean IOP was 35.38±7.16 mm Hg before surgery and 15.52±4.22 mm Hg 1y after surgery(P<0.01).The average number of anti-glaucoma medication was 2.8±1.2(2-4)preoperation and 0.6±1.3(0-3)1y postoperation(P<0.01).The success rate of the operation was 93.33%.Complete success rate was 66.67%,qualified success rate was 26.67%,and 6.66%of unsuccessful cases required reoperation.EVFW of all cases was grade 2-4,and the percentages of grade 2,3 and 4 were 33.33%,40.0%and 26.67%,respectively.The distribution and percentage of EVFW were inferior(36%),nasal(28%),superior(20%),and temporal(16%).The EVFW grade of complete success patients was 3.4±0.6(3-4),and that of qualified success patients was 2.6±1.0(2-4).The larger the range of EVFW,the lower the IOP,and the better the IOP reduction effect.CONCLUSION:During GATT surgery,pressurized irrigation of anterior chamber to check EVFW can reduce the outflow resistance of aqueous humor and increase the effect of postoperative IOP.The range of EVFW is negatively correlated with postoperative IOP.Therefore,EVFW may be a valuable prognostic indicator for the success of GATT surgery.
基金supported by the National Natural Science Foundation of China(82073160).
文摘Objective The popularization of gastroenteroscopy and the introduction of comfortable medical care have further promoted the growth of people's demand,especially the demand for painless endoscopy.This cross-sectional study aims to investigate the current situation and change in county people's demand for endoscopy to promote the development of endoscopy centers in county hospitals in southeast China.Methods From October to December 2021,patients and their family members who came to the Gastroenterology Department in Suichang County People's Hospital of Zhejiang Province were randomly selected to complete the questionnaire.A total of 838 valid questionnaires were collected.Additionally,the original software data of the Endoscopy Center were sampled and retrieved(from October to December every year from 2018 to 2021)for statistical analysis of real-world data.Those who would choose painless endoscopy the next time in the valid questionnaires were included in the painless endoscopy group,while those who would choose ordinary endoscopy the next time were included in the ordinary endoscopy group.Results The stepwise forward binary logistic regression model analysis showed that,patients with“secondhand smoke exposure”were more willing to choose painless endoscopy(OR=1.459,95%CI:1.050-2.028,p=0.025).However,patients with an education level of“primary and below”and“junior high school”,and patients who are suffering from“currently experiencing abdominal distension”,were more willing to choose ordinary endoscopy(OR=0.270,95%CI:0.149-0.488,p<0.001;OR=0.528,95%CI:0.330-0.845,p=0.008;OR=0.536,95%CI:0.334-0.861,p=0.010).Patients with previous experience in painless endoscopy tended to choose painless endoscopy the next time,while patients with previous experience in ordinary endoscopy tended to choose ordinary endoscopy the next time(χ^(2)=140.97,p<0.001).From 2018 to 2021,the proportion of painless endoscopy has increased yearly(p<0.001).Most patients indicated that they would“regularly review gastroenteroscopy”(477/838,56.9%).Conclusions With Suichang County of Zhejiang Province as the representative,the demand for painless endoscopy for people's gastrointestinal cancer detection in southeast China has been increasing yearly.The development of endoscopy centers in county-level hospitals can basically meet the demand growth.Meanwhile,advanced concepts such as comfortable medical care and regular follow-up are gradually popularized at the grassroots level in southeast China.
基金Supported by Class A Project of Scientific Research Development Program of Colleges and Universities in Shandong Province (J17KA155)。
文摘The diseases of sweet cherry caused by viruses and viroids have occurred in the main cherry producing areas of China and are increasing year by year, which has become an important factor affecting the yield and quality of sweet cherry. For this reason, this paper elaborated the prevention and countermeasures of virus diseases from six aspects, including soil treatment, cultivation of disease-free seedlings, prevention of disease and pest damage, reasonable pruning, water management, and treatment of virus diseases, in order to provide technical guidance for the disease resistance, high quality and high yield of facility cherry, as well as information reference for the further improvement of the technical system of virus disease prevention and cultivation of facility cherry.
基金Supported by Guangxi Provincial Natural Science Foundation ( 2011GXNSFA018080)General Science Research Program of Educational Commission of Guangxi Province of China [( 2009) No. 25]Phase Ⅱ of the Program for the Construction of Guangxi Key Laboratory of Environmental Engineering and Protection and Assessment
文摘[Objective] The aim was to study the immobilization of laccase from Canoderma lucidum in three different sol-gel systems to find out the optimum ma- terials for laccase immobilization. [ Method ] Laccase from G. lucidum LYL 263 was immobilized in sodium alginate-gelatin, sodium alginate-chitosan and sodium alginate-gelatin-chitosan sol-gel systems, respectively; and the laccase activity was preliminarily analyzed. [ Result] The activity of laccase immobilized in sodium alginate-gelatin-chitosan was 2.14 folds and 2.75 folds respectively, compared to sodium alginate-gelatin and sodium alginate-chitosan; and this optimum system contained sodium alginate 2.0% , gelatin 1.0%, chitosan 0.3% and calcium chloride 56%. Benzoic acid was firstly used to embed immobilized laccase in this study, and single-factor experiments revealed that the activity of laccase could be effectively improved by suitable content of benzoic acid. The optimal conditions for laccase immobilization in the system were be^oie acid 2 retool/L, glutaraldehyde 0.32%, cross-linking reaction time 50 rain and enzyme concentration 10.0% ; and then the activity of the immobilized enzyme reached 635.7 U/g with these conditions. The thermal stability of the immobilized laccase was higher than free lac- case, and the activity of immobilized enzyme treated by freeze-drying was 1.59 folds compared to the non-freeze-dried, but the freeze-dried immobilized laccase had poor operational stability. [ Conclusion] The compositions of the material had significant influence on laccase immobilization and this study will provide reference to select materials for immobilization of laccase from G. lacidum LYL 263.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61921002,62171098,and 92163204)。
文摘The photonic crystal structure has attracted much attention due to its ability to confine light.In this paper,we present our study on an improved Smith-Purcell radiation from a simple metal photonic crystal excited by moving electrons.Different from the wide-band Smith-Purcell radiation from a single metal grating,the results show that the injected electrons could induce more dipole oscillations inside the multi-grating structure,and it leads to the enhancement of the radiation intensity.In addition,there are strong resonances in metal multi-grating structure,and the resonance characteristics may narrow the radiation band,which leads to a radiation with an obvious peak in the spectrum.Therefore,the multi-grating structure has the ability to enhance the radiation intensity and shape the radiation frequency band.By optimizing the structure parameters,coherent and tunable Smith-Purcell radiation can be realized,and it provides a potential way to develop band-controllable light or THz radiation source.
文摘目的探讨疫情期间正念干预对护理本科生心理弹性及职业认同感的影响及其机制,为提升护理本科生心理健康状况和职业认同感提供有力证据。方法2021年4月25—30日从北京市某高校完成预调查的研究对象中随机选取108名护理学生,其中有52人作为干预组成员进行线上线下相结合的正念干预,56人作为对照组成员进行空白对照,分别利用心理弹性量表(Resilience Style Questionnaire,RSQ)、护生职业认同量表(Professional Identity for Nurse Students Questionnaire,PINSQ)评估两组成员在干预前、干预后1周、干预后3个月后(随访时)的心理弹性及职业认同感水平。利用SAS 9.4软件,采用广义估计方程评价干预效果,采用Process程序检验心理弹性的中介效应。结果干预后,干预组心理弹性高于对照组(P<0.05);随访时,干预组和对照组的心理弹性差异无统计学意义(P>0.05)。干预组学生在干预后和随访时心理弹性相比干预前均有所提高(P<0.05),随访时和干预后相比,心理弹性有所下降(P<0.05);对照组各个时间点的心理弹性水平无变化(P>0.05)。干预后,干预组职业认同感得分高于对照组(P<0.05);随访时,干预组的职业认同感高于对照组(P<0.01)。干预组职业认同感在各时间点的提升均具有统计学意义(P<0.05);对照组各个时间点的职业认同感水平差异无统计学意义(P>0.05)。正念干预可通过影响心理弹性水平进而影响职业认同感,心理弹性在其中的中介效应占比为23.67%。结论正念干预可有效提升疫情期间护理本科生的心理弹性和职业认同感水平,可为后续的心理干预和研究提供依据。
