Stellar parameters of main sequence turn-off star candidates observed with LAMOST and Kepler

Main sequence turn-off(MSTO) stars have advantages as indicators of Galactic evolution since their ages can be robustly estimated from atmospheric parameters. Hundreds of thousands of MSTO stars have been selected from the LAMOST Galactic survey to study the evolution of the Galaxy,and it is vital to derive accurate stellar parameters. In this work, we select 150 MSTO star candidates from the MSTO star sample of Xiang that have asteroseismic parameters and determine accurate stellar parameters for these stars by combining asteroseismic parameters deduced from Kepler photometry and atmospheric parameters deduced from LAMOST spectra. With this sample, we examine the age determination as well as the contamination rate of the MSTO star sample. A comparison of age between this work and Xiang shows a mean difference of 0.53 Gyr(7%) and a dispersion of 2.71 Gyr(28%).The results show that 79 of the candidates are MSTO stars, while the others are contaminations from either main sequence or sub-giant stars. The contamination rate for the oldest stars is much higher than that for younger stars. The main cause for the high contamination rate is found to be the relatively large systematic bias in the LAMOST surface gravity estimates.

Binary Star Fractions from the LAMOST DR4

Stellar systems composed of single, double, triple or higher-order systems are rightfully regarded as the fundamental building blocks of the Milky Way. Binary stars play an important role in formation and evolution of the Galaxy. Through comparing the radial velocity variations from multiepoch observations, we analyze the binary fraction of dwarf stars observed with LAMOST. Effects of different model assumptions, such as orbital period distributions on the estimate of binary fractions,are investigated. The results based on log-normal distribution of orbital periods reproduce the previous complete analyses better than the power-law distribution. We find that the binary fraction increases with Teff and decreases with [Fe/H]. We first investigate the relation between α-elements and binary fraction in such a large sample as provided by LAMOST. The old stars with high [α/Fe] dominate with a higher binary fraction than young stars with low [α/Fe]. At the same mass, earlier forming stars possess a higher binary fraction than newly forming ones, which may be related with evolution of the Galaxy.

Applicability of Community Periodontal Index Teeth and Random Half-mouth Examination to Gingival Bleeding Assessment in Untreated Adult Population in Beijing

Objective To assess whether Community Periodontal Index (CPI) teeth and random half-mouth methods are representative of full-mouth method in gingival bleeding examination. Methods Data from 1000 untreated adults (age > 18) collected in Beijing from January 2000 to January 2001 were utilized in the analysis. Half of the subjects were examined by Gingival Bleeding Index (GBI) and the other half by Sulcus Bleeding Index (SBI). The data were sorted out and calculated according to CPI teeth and random half-mouth teeth methods. The results of the 2 methods were separately compared with those of full-mouth examination. Results There was a significant difference between CPI teeth method and full-mouth examination (P<0.05) in both GBI and SBI. In contrast, compared with full-mouth examination, significant difference was not observed in diagonal or ipsilateral half-mouth results in SBI (P>0.05), nor in diagonal half-mouth results in GBI (P>0.05) Conclusions The results of CPI teeth method on gingival bleeding could not reflect the full-mouth situation. Ipsilateral and diagonal half-mouth results can serve as a substitute for full-mouth results in SBI, while diagonal half-mouth results in GBI.

Variations of helioseismic parameters due to magnetic field generated by a flux transport model

The change of sound speed has been found at the base of the convection during the solar cycles,which can be used to constrain the solar internal magnetic field.We aim to check whether the magnetic field generated by the solar dynamo can lead to the cyclic variation of the sound speed detected through helioseismology.The basic configuration of magnetic field in the solar interior was obtained by using a Babcock-Leighton(BL)type flux transport dynamo.We reconstructed one-dimensional solar models by assimilating magnetic field generated by an established dynamo and examined their influences on the structural variables.The results show that magnetic field generated by the dynamo is able to cause noticeable change of the sound speed profile at the base of the convective zone during a solar cycle.Detailed features of this theoretical prediction are also similar to those of the helioseismic results in solar cycle 23 by adjusting the free parameters of the dynamo model.

Mechanism research of pirarubicin postoperative immediately bladder irrigation combined compound matrine injection on treating superficial bladder cancer

Objective:Investigate the mechanism of Pirarubicin postoperative immediately bladder irrigation combined compound matrine injection on treating superficial bladder cancer, thus to provide assistance for clinical therapy of superficial bladder cancer.Methods:A total of 90 cases of patients with superficial bladder cancer treated in our hospital were selected, and randomly divided to be control group and combination group, 45 cases for each. For patients in control group, treatment of Pirarubicin postoperative immediately bladder irrigation was provided after transurethral resection of bladder tumors. For patients in combination group, combined treatment of Pirarubicin postoperative immediately bladder irrigation and compound matrine injection were provided after transurethral resection of bladder tumors. T lymphocyte subsets, cytokines, liver and renal functions of patients in each group were detected before and after treatment.Results: No statistical difference showed on T lymphocyte subsets, cytokines, liver and renal functions between two groups of patients with superficial bladder cancer before and after treatment. Compared with prior treatment, CD8+, cytokines (IFN-γ and IL-2), liver function indexes (AST and ALT) and renal function indexes (BUN and Cre) were significantly increased in two groups of patients after treatment, while T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) and cytokines (TNF-α, IL-6 and CRP) were significantly decreased. Differences showed statistical significance. After combined treatment given, T lymphocyte subsets (CD3+, CD4+ and CD4+/CD8+) and cytokines (IFN-γ and IL-2) in combination group were significantly higher than in control group after treatment, cytokines (TNF-α, IL-6 and CRP), CD8+, liver function indexes (AST and ALT) and renal function indexes (BUN and Cre) were significantly lower than in control group after treatment. Differences between the two groups showed statistical significance.Conclusion:Combination of Pirarubicin postoperative immediately bladder irrigation and compound matrine injection could enhance immune functions, improve inflammatory reactions and decrease chemotherapeutics toxicities for patients with superficial bladder cancer. It is of great significance on clinical therapy for those patients.

Jinbei Oral Liquid ameliorates bleomycin-induced idiopathic pulmonary fibrosis in rats via reversion of Th1/Th2 shift

Objective:Idiopathic pulmonary fibrosis(IPF)is a progressive and lethal interstitial lung disease with high mortality.The pivotal role of Th1/Th2 immunological balance in the development and progression of IPF has been demonstrated previously.This study aimed to evaluate the effect of Jinbei Oral Liquid(JBOL)on IPF and its relationship with Th1/Th2 shift.Methods:Rats were divided into six groups:control group,model group(bleomycin),pirfenidone group(positive group,54 mg/kg,i.g.)and JBOL(5.4,10.8 and 21.6 mL/kg,i.g.)groups.The rat model was established by an intratracheal instillation of bleomycin(BLM,5 mg/kg).One day after injection of BLM,pirfenidone or JBOL was given to rats once daily within 28 consecutive days,respectively.Positron emission tomography/computed tomography(PET/CT)was performed on the treated rats.The extent of alveolitis and fibrosis was observed by H&E and Masson trichrome staining.The contents of TGF-β1,TNF-α,IL-4 and IFN-γwere further quantified by ELISA assay.Results:PET/CT and histopathological evidence showed the ability of JBOL to attenuate bleomycininduced alveolitis and fibrosis extent,and the alveolitis lesion score was markedly decreased compared with the model group.The increased expression of inflammatory cytokines TGF-β1 and TNF-αinduced by bleomycin was also suppressed by JBOL.The Th1 response was limited by the reduced IFN-γafter BLM administration,and the Th2 response predominated significantly marked by the increased IL-4.JBOL could increase the level of IFN-γand markedly increased the ratio of IFN-γ/IL-4.Conclusion:These findings suggested that JBOL may attenuate BLM-induced idiopathic pulmonary fibrosis via reducing inflammatory cell infiltration,pro-inflammatory cytokine release and excessive collagen deposition in rats.One of the mechanisms is the reversion of Th1/Th2 shift caused by BLM.

Multi-center investigation of the clinical and pathological characteristics of inflammatory breast cancer based on Chinese Society of Breast Surgery(CSBrs-007)

Background:Inflammatory breast cancer(IBC)is an aggressive type of cancer with poor prognosis and outcomes.This study aimed to investigate clinicopathological features,molecular characteristics,and treatments among Chinese patients diagnosed with IBC.Methods:We collected data of 95 patients with IBC who were treated by members of the Chinese Society of Breast Surgery,from January 2017 to December 2018.The data,including demographic characteristics,pathological findings,surgical methods,systemic treatment plans,and follow-up,were obtained using a uniform electronic questionnaire.The clinicopathological features of different molecular types in patients without distant metastases were compared using the Kruskal-Wallis(H)test followed by post hoc analyses.Results:Lymph node metastasis was noted in 75.8%of all patients,while distant metastasis was noted in 21.4%.Pathological findings indicated invasive ductal and lobular carcinomas in 86.8%and 5.3%of cases,respectively.Hormone receptor-positive(HR+)/human epidermal growth factor receptor 2-negative(HER2-)(41.5%)and HR-/HER2+(20.1%)were the most common biologic subtypes,followed by HR+/HER2+(19.1%)and HR-/HER2-(19.1%).Stage III IBC was treated via pre-operative neoadjuvant chemotherapy in 87.7%of the cases,predominantly using anthracycline and taxanes.A total of 91.9%of patients underwent surgical treatment.Among them,77.0%of the patients underwent modified radical mastectomy,8.1%of whom also underwent immediate breast reconstruction.The Kruskal-Wallis test revealed that the efficacy of chemotherapy significantly differed among those with HR+/HER2-and HR-/HER2-tumors(adjusted P=0.008),and Ki-67 expression significantly differed in HR-/HER2+and HR+/HER2+molecular subtypes(adjusted P=0.008).Conclusion:Our study provides novel insight into clinicopathological characteristics and treatment status among patients with IBC in China,and might provide a direction and basis for further studies.