The excitation of H2O masers usually needs very high density gas,hence it can serve as a marker of dense gas in HⅡ region. We selected a sample of H2O maser sources from Plume et al. （four with, and four without det...The excitation of H2O masers usually needs very high density gas,hence it can serve as a marker of dense gas in HⅡ region. We selected a sample of H2O maser sources from Plume et al. （four with, and four without detected CS（J = 7 - 6） emission）, and observed them in ^13CO（J=1-0） and C^18O （J=1-0）. C^18O （J=1-0） emission was detected only in three of the sources with detected CS（J=7-6） emission. An analysis combined with some data in the literature suggests that these dense cores may be located at different evolutionary stages. Multi-line observation study may provide us clues on the evolution of massive star forming regions and the massive stars themselves.展开更多
L-glutamic acid(LA)is a bio-based,non-toxic,environmentally friendly material derived from biomass.The present study reports the application of Passerini three-component polymerization(P-3CP)for the straightforward pr...L-glutamic acid(LA)is a bio-based,non-toxic,environmentally friendly material derived from biomass.The present study reports the application of Passerini three-component polymerization(P-3CP)for the straightforward preparation of LA-based light-responsive polyesters(PLTDs)under mild conditions.PLTDs with molar masses up to 8500 g/mol and high yields exceeding 90%are obtained.The chemical structures and light-responsive self-immolative behavior of PLTDs are comprehensively characterized by employing ultraviolet-visible(UV-Vis)spectroscopy,size exclusion chromatography(SEC),nuclear magnetic resonance(NMR)spectroscopy,and liquid chromatography mass spectrometry(LC-MS).Meanwhile,monodisperse PLTD-based doxorubicin-loaded nanoparticles(PLTD-DOX-NP)(size=193 nm,PDI=0.018)are formulated by nanoprecipitation method.Upon light-induced depolymerization,the PLTD-DOX-NP undergoes rapid decomposition,resulting in a burst release of 80%cargo within 13 s.Furthermore,according to biological toxicity tests,the PLTD-NP possesses adequate biosafety,both before and after irradiation.Overall,the incorporation of P-3CP with biorenewable LA-based monomer adheres to the principles of green chemistry,significantly simplifying the synthetic pathway of light-responsive polymers.展开更多
基金Supported by the National Natural Science Foundation of China.
文摘The excitation of H2O masers usually needs very high density gas,hence it can serve as a marker of dense gas in HⅡ region. We selected a sample of H2O maser sources from Plume et al. （four with, and four without detected CS（J = 7 - 6） emission）, and observed them in ^13CO（J=1-0） and C^18O （J=1-0）. C^18O （J=1-0） emission was detected only in three of the sources with detected CS（J=7-6） emission. An analysis combined with some data in the literature suggests that these dense cores may be located at different evolutionary stages. Multi-line observation study may provide us clues on the evolution of massive star forming regions and the massive stars themselves.
基金This work was financially supported by the International Science and Technology Assistance Program of the Ministry of Science and Technology(No.KY202001016)Shandong Provincial Natural Science Foundation Magnitude Fundamental Research,China(No.ZR2022ZD11)Qingdao New Energy Shandong Laboratory Open Project(No.QNESL OP202312).
文摘L-glutamic acid(LA)is a bio-based,non-toxic,environmentally friendly material derived from biomass.The present study reports the application of Passerini three-component polymerization(P-3CP)for the straightforward preparation of LA-based light-responsive polyesters(PLTDs)under mild conditions.PLTDs with molar masses up to 8500 g/mol and high yields exceeding 90%are obtained.The chemical structures and light-responsive self-immolative behavior of PLTDs are comprehensively characterized by employing ultraviolet-visible(UV-Vis)spectroscopy,size exclusion chromatography(SEC),nuclear magnetic resonance(NMR)spectroscopy,and liquid chromatography mass spectrometry(LC-MS).Meanwhile,monodisperse PLTD-based doxorubicin-loaded nanoparticles(PLTD-DOX-NP)(size=193 nm,PDI=0.018)are formulated by nanoprecipitation method.Upon light-induced depolymerization,the PLTD-DOX-NP undergoes rapid decomposition,resulting in a burst release of 80%cargo within 13 s.Furthermore,according to biological toxicity tests,the PLTD-NP possesses adequate biosafety,both before and after irradiation.Overall,the incorporation of P-3CP with biorenewable LA-based monomer adheres to the principles of green chemistry,significantly simplifying the synthetic pathway of light-responsive polymers.
