Cuscuta sinensis is a traditional Chinese medicine commonly used in traditional medicine,known for its liver and kidney tonifying effects,sperm fixing and urine reduction properties,fetus calming abilities,eye brighte...Cuscuta sinensis is a traditional Chinese medicine commonly used in traditional medicine,known for its liver and kidney tonifying effects,sperm fixing and urine reduction properties,fetus calming abilities,eye brightening qualities,and diarrhea stopping capabilities.Modern pharmacological studies have focused on its chemical components such as flavonoids,polysaccharides,alkaloids,steroids,and other bioactive compounds.These studies have revealed its various pharmacological effects,including hormone secretion regulation,ovulation promotion,sperm protection,testicular development promotion,and sperm formation.It is extensively utilized in the treatment of urological and reproductive system diseases,such as male sexual dysfunction,polycystic ovary syndrome,premature ovarian failure,weak spermatozoa,and infertility.This article provides a review of recent advancements in the application of Cuscuta sinensis in the genitourinary system,aiming to enhance the clinical application of Cuscuta sinensis preparations.展开更多
Arrowsmith,a literature retrieval tool,was used to explore the theoretical pharmacological mechanism of action of Xuefu Zhuyu decoction and its single herb against erectile dysfunction.Cytoscape 3.6.1 software was use...Arrowsmith,a literature retrieval tool,was used to explore the theoretical pharmacological mechanism of action of Xuefu Zhuyu decoction and its single herb against erectile dysfunction.Cytoscape 3.6.1 software was used to analyze the correlation between the components of Xuefu Zhuyu decoction and the identified mechanism of action.Different herbs in Xuefu Zhuyu decoction may play a therapeutic role by regulating iNOS,COX-2,mTOR,Wnt,AMPK,Nrf2,TLR4,CYP2D6,BDNF,MAPK,Akt,STAT3,PI3K,ERK1,P38MAPK,JNK,VEGF,and other targets.The treatment of erectile dysfunction with Xuefu Zhuyu decoction embodied the multicomponent,multitarget,and multipathway.The Arrowsmith tool retrieval and analysis provided a scientific basis for further elucidation of the mechanism of Xuefu Zhuyu decoction against erectile dysfunction.展开更多
文摘Cuscuta sinensis is a traditional Chinese medicine commonly used in traditional medicine,known for its liver and kidney tonifying effects,sperm fixing and urine reduction properties,fetus calming abilities,eye brightening qualities,and diarrhea stopping capabilities.Modern pharmacological studies have focused on its chemical components such as flavonoids,polysaccharides,alkaloids,steroids,and other bioactive compounds.These studies have revealed its various pharmacological effects,including hormone secretion regulation,ovulation promotion,sperm protection,testicular development promotion,and sperm formation.It is extensively utilized in the treatment of urological and reproductive system diseases,such as male sexual dysfunction,polycystic ovary syndrome,premature ovarian failure,weak spermatozoa,and infertility.This article provides a review of recent advancements in the application of Cuscuta sinensis in the genitourinary system,aiming to enhance the clinical application of Cuscuta sinensis preparations.
文摘Arrowsmith,a literature retrieval tool,was used to explore the theoretical pharmacological mechanism of action of Xuefu Zhuyu decoction and its single herb against erectile dysfunction.Cytoscape 3.6.1 software was used to analyze the correlation between the components of Xuefu Zhuyu decoction and the identified mechanism of action.Different herbs in Xuefu Zhuyu decoction may play a therapeutic role by regulating iNOS,COX-2,mTOR,Wnt,AMPK,Nrf2,TLR4,CYP2D6,BDNF,MAPK,Akt,STAT3,PI3K,ERK1,P38MAPK,JNK,VEGF,and other targets.The treatment of erectile dysfunction with Xuefu Zhuyu decoction embodied the multicomponent,multitarget,and multipathway.The Arrowsmith tool retrieval and analysis provided a scientific basis for further elucidation of the mechanism of Xuefu Zhuyu decoction against erectile dysfunction.
