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3DSTI评估胃癌患者经蒽环类药物化疗后左心室功能变化的临床应用 被引量:2
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作者 张玮 黄敬垣 李浩 《世界华人消化杂志》 CAS 2018年第36期2127-2132,共6页
目的探讨三维斑点追踪成像(three-dimensional speckle tracking image, 3DSTI)评估胃癌(gastric cancer, GC)患者经蒽环类药物化疗后左心室功能变化的临床应用.方法选取在嘉兴市第二医院行GC术后接受蒽环类药物化疗(采用ECF-L联合化疗... 目的探讨三维斑点追踪成像(three-dimensional speckle tracking image, 3DSTI)评估胃癌(gastric cancer, GC)患者经蒽环类药物化疗后左心室功能变化的临床应用.方法选取在嘉兴市第二医院行GC术后接受蒽环类药物化疗(采用ECF-L联合化疗方案)的35例GC患者作为研究对象(化疗组),于化疗前和化疗第2周期、第4周期及第6周期后行常规超声心动图及3DSTI检查,比较化疗前后左心室功能参数.同期选取30例健康志愿者作为对照组.结果化疗组在化疗第4周期、第6周期后的左室整体纵向应变(global longitudinal strain, GLS)和整体面积应变(global area strain, GAS)较对照组、化疗前、化疗第2周期后明显下降,差异均有统计学意义(P<0.05);化疗组在化疗前、化疗第2周期、第4周期及第6周期后的左室短轴缩短率、左室射血分数、整体圆周应变以及整体径向应变与对照组比较差异均无统计学意义(P>0.05).结论3DSTI能有效监测蒽环类药物对GC患者左心室功能的早期损害,其中GAS及GLS参数的敏感性较高,可为临床治疗提供参考. 展开更多
关键词 超声心动描记术 三维斑点追踪成像 蒽环类药物 胃癌 左心室功能
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Contrast-enhanced ultrasound predicts microvascular invasion in patients with hepatocellular carcinoma 被引量:1
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作者 jing-yuan huang Zhi-Liang huang +1 位作者 Zhe Yang Xiao-Ping Zheng 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2022年第6期609-613,共5页
To the Editor:The presence of microvascular invasion(MVI)in hepatocellular carcinoma(HCC)is an important indicator for HCC recurrence and poor prognosis[1].Determining the preoperative MVI status is helpful for guidin... To the Editor:The presence of microvascular invasion(MVI)in hepatocellular carcinoma(HCC)is an important indicator for HCC recurrence and poor prognosis[1].Determining the preoperative MVI status is helpful for guiding clinical treatment and improving prognosis.Currently,MVI diagnosis is achieved primarily by postoperative histopathology,which makes it difficult to provide a definite diagnosis before surgery.However,significant advancements in imaging technology have begun to allow clinicians to make a diagnosis of HCC MVI prior to surgery.In this study,we used contrast-enhanced ultrasound(CEUS)to observe the characteristics of HCC enhancement patterns and quantitatively analyze the changes in HCC blood perfusion parameters to explore the value of CEUS in evaluating HCC MVI. 展开更多
关键词 INVASION DIAGNOSIS HEPATOCELLULAR
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