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Molecular mechanism and therapeutic targeting of necrosis,apoptosis,pyroptosis,and autophagy in cardiovascular disease 被引量:4
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作者 Pan Li Xiao-Rong Dong +4 位作者 Bei Zhang Xin-Tong Zhang jing-zhuo liu De-Sheng Ma Li Ma 《Chinese Medical Journal》 SCIE CAS CSCD 2021年第22期2647-2655,共9页
Cell death occurs in various tissues and organs in the body.It is a physiological or pathological process that has different effects.It is of great significance in maintaining the morphological function of cells and c... Cell death occurs in various tissues and organs in the body.It is a physiological or pathological process that has different effects.It is of great significance in maintaining the morphological function of cells and clearing abnormal cells.Pyroptosis,apoptosis,and necrosis are all modes of cell death that have been studied extensively by many experts and scholars,including studies on their effects on the liver,kidney,the heart,other organs,and even the whole body.The heart,as the most important organ of the body,should be a particular focus.This review summarizes the mechanisms underlying the various cell death modes and the relationship between the various mechanisms and heart diseases.The current research status for heart therapy is discussed from the perspective of pathogenesis. 展开更多
关键词 Cell death APOPTOSIS NECROSIS PYROPTOSIS AUTOPHAGY Pathogenesis Treatment
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