The fluorescence property of bovine serum albumin was investigated in the presence of PEGs of different molecular weights. Based on our results, we propose that PEGs of different molecular weights bind to albumin in t...The fluorescence property of bovine serum albumin was investigated in the presence of PEGs of different molecular weights. Based on our results, we propose that PEGs of different molecular weights bind to albumin in the pH 7.4 aqueous solution, but only when the polymer size is larger than the protein size, one polymer chain may bind to multiple proteins and cause the proteins to aggregate.展开更多
基金financially supported by the National Natural Science Foundation of China(No.21434008)
文摘The fluorescence property of bovine serum albumin was investigated in the presence of PEGs of different molecular weights. Based on our results, we propose that PEGs of different molecular weights bind to albumin in the pH 7.4 aqueous solution, but only when the polymer size is larger than the protein size, one polymer chain may bind to multiple proteins and cause the proteins to aggregate.
