BACKGROUND:The complications of systemic inflammatory response syndrome(SIRS)include acute lung injury,acute kidney injury,shock,and multiple organ dysfunction syndrome(MODS).In recent years,how to clear inflammatory ...BACKGROUND:The complications of systemic inflammatory response syndrome(SIRS)include acute lung injury,acute kidney injury,shock,and multiple organ dysfunction syndrome(MODS).In recent years,how to clear inflammatory mediators has become a hot topic in critical care medicine.Researchers hypothesize that continuous blood purification(CBP) can effectively eliminate a variety of inflammatory mediators which participate in the occurrence of MODS and adjust the immune imbalance.This study aimed to observe the effects of CBP in MODS patients.METHODS:In this retrospective clinical study,a total of 38 MODS patients,18 males and 20 females,were enrolled.After conventional therapy,all the patients received CBP.Biochemistry,blood gas analysis,oxygenation index,mean arterial blood pressure(MAP),acute physiology and chronic health evaluation(APACHE) II scores were monitored.RESULTS:After CBP,the vital signs of patients were rapidly stable,and electrolyte disorders and acid-base imbalance were corrected.Renal function,blood gas,oxygenation index were all improved.MAP was increased,and APACHE II score was significantly decreased.All patients had good tolerance,stable hemodynamics,and no obvious adverse reaction on CBP compared with pre-CBP.CONCLUSION:CBP can effectively clean toxins,correct electrolyte acid-base balance,and improve systemic inflammatory response syndrome and the organ function of MODS patients.展开更多
The flow on the Wiener space associated to a tangent process constructed by Cipriano and Cruzeiro, as well as by Gong and Zhang does not allow to recover Driver’s Cameron-Martin theorem on Riemannian path space. The ...The flow on the Wiener space associated to a tangent process constructed by Cipriano and Cruzeiro, as well as by Gong and Zhang does not allow to recover Driver’s Cameron-Martin theorem on Riemannian path space. The purpose of this work is to refine the method of the modified Picard iteration used in the previous work by Gong and Zhang and to try to recapture and extend the result of Driver. In this paper, we establish the existence and uniqueness of a flow associated to a Cameron-Martin type vector field on the path space over a Riemannian manifold.展开更多
文摘BACKGROUND:The complications of systemic inflammatory response syndrome(SIRS)include acute lung injury,acute kidney injury,shock,and multiple organ dysfunction syndrome(MODS).In recent years,how to clear inflammatory mediators has become a hot topic in critical care medicine.Researchers hypothesize that continuous blood purification(CBP) can effectively eliminate a variety of inflammatory mediators which participate in the occurrence of MODS and adjust the immune imbalance.This study aimed to observe the effects of CBP in MODS patients.METHODS:In this retrospective clinical study,a total of 38 MODS patients,18 males and 20 females,were enrolled.After conventional therapy,all the patients received CBP.Biochemistry,blood gas analysis,oxygenation index,mean arterial blood pressure(MAP),acute physiology and chronic health evaluation(APACHE) II scores were monitored.RESULTS:After CBP,the vital signs of patients were rapidly stable,and electrolyte disorders and acid-base imbalance were corrected.Renal function,blood gas,oxygenation index were all improved.MAP was increased,and APACHE II score was significantly decreased.All patients had good tolerance,stable hemodynamics,and no obvious adverse reaction on CBP compared with pre-CBP.CONCLUSION:CBP can effectively clean toxins,correct electrolyte acid-base balance,and improve systemic inflammatory response syndrome and the organ function of MODS patients.
基金Supported by the National Natural Science Foundation of China(No.10601066)the financial support of the Fundamental Research Funds for Central Universitiesthe Research Funds of Renmin University of China(11XNI008)
文摘The flow on the Wiener space associated to a tangent process constructed by Cipriano and Cruzeiro, as well as by Gong and Zhang does not allow to recover Driver’s Cameron-Martin theorem on Riemannian path space. The purpose of this work is to refine the method of the modified Picard iteration used in the previous work by Gong and Zhang and to try to recapture and extend the result of Driver. In this paper, we establish the existence and uniqueness of a flow associated to a Cameron-Martin type vector field on the path space over a Riemannian manifold.
