Pre-and post-selected(PPS) measurement, especially the weak PPS measurement, has been proved to be a useful tool for measuring extremely tiny physical parameters. However, it is difficult to retain both the attainable...Pre-and post-selected(PPS) measurement, especially the weak PPS measurement, has been proved to be a useful tool for measuring extremely tiny physical parameters. However, it is difficult to retain both the attainable highest measurement sensitivity and precision with the increase of the parameter to be measured. Here, a modulated PPS measurement scheme based on coupling-strength-dependent modulation is presented with the highest sensitivity and precision retained for an arbitrary coupling strength. This idea is demonstrated by comparing the modulated PPS measurement scheme with the standard PPS measurement scheme in the case of unbalanced input meter. By using the Fisher information metric, we derive the optimal pre-and post-selected states, as well as the optimal coupling-strength-dependent modulation without any restriction on the coupling strength. We also give the specific strategy of performing the modulated PPS measurement scheme, which may promote practical application of this scheme in precision metrology.展开更多
We introduce a modified weak value that is related to the mean value of input meter variable.With the help of the modified weak value,the validity conditions for various modified versions of weak value formalism are i...We introduce a modified weak value that is related to the mean value of input meter variable.With the help of the modified weak value,the validity conditions for various modified versions of weak value formalism are investigated,in terms of the dependence of the pointer shift on the mean value of the input meter.The weak value formalism,often used to represent the pointer shift,with the modified weak value is of great use in simplifying calculations and giving guidance of practical experiments whenever the mean value of the input meter variable is nonzero.The simulation in a qubit system is presented and coincident well with our theoretical result.展开更多
We theoretically introduce the statistical uncertainty of photon number and phase error to discuss the precision of parameters to be measured based on weak measurements. When the photon counting scheme is used, we dis...We theoretically introduce the statistical uncertainty of photon number and phase error to discuss the precision of parameters to be measured based on weak measurements. When the photon counting scheme is used, we discuss the relative accuracy of the system in the presence of phase error by using the orthogonal and nonorthogonal pre-and postselected states, respectively. When using the measurement scheme of pointer shift, we discuss the measurement accuracy in the presence of phase error, pointer resolution, and statistical uncertainty. These results give a guide way to get the smallest relative precision and deepen our understanding about weak measurement.展开更多
The strong chiroptical effect is highly desirable and has a wide range of applications in biosensing, chiral catalysis,polarization tuning, and chiral photo detection. In this work, we find a simple method to enhance ...The strong chiroptical effect is highly desirable and has a wide range of applications in biosensing, chiral catalysis,polarization tuning, and chiral photo detection. In this work, we find a simple method to enhance the reflection circular dichroism(CDR) by placing the planar anisotropic chiral metamaterials(i.e., Z-shaped PACMs) on the interface of two media(i.e., Z-PCMI) with a large refractive index difference. The maximum reflection CDR from the complex system can reach about 0.840 when the refractive index is set as ntop = 4.0 and nbottom = 1.49, which is approximately three times larger than that of placing the Z-shaped PACMs directly on the substrate(i.e., Z-PCMS). While the minimum reflection CDR is 0.157 when the refractive index is set as ntop = 1.0 and nbottom = 1.49. So we can get a large available range of reflection CDR from -0.840 to -0.157. Meanwhile, the transmission CDT remains unchanged with the refractive index ntop increment. Our in-depth research indicates that the large reflection CDR is derived from the difference of non-conversion components of the planar anisotropic chiral metamaterials’ reflection matrices. In short, we provide a simple and practical method to enhance the chiroptical effect by changing the refractive index difference between two media without having to design a complex chiral structure.展开更多
The Golgi apparatus is one of the important organelles,where the final processing and packaging of cellular secretions(such as proteins)are completed.The disorder of Golgi apparatus structure and function will induce ...The Golgi apparatus is one of the important organelles,where the final processing and packaging of cellular secretions(such as proteins)are completed.The disorder of Golgi apparatus structure and function will induce many diseases.Therefore,monitoring the morphological structure of Golgi apparatus is crucial for the diagnosis and treatment of relevant diseases.In order to achieve Golgi apparatus-targeting imaging,the strategy of targeting unit inheritance was adopted and carbon dots(CDs)with Golgi apparatus-targeting ability were synthesized by one-step hydrothermal method with L-ascorbic acid with high reactivity and reducibility as the carbon source and L-cysteine as the targeting unit.CDs have a certain amount of cysteine residues on their surface,and have excitation dependence,satisfactory fluorescence and cysteine residues stability and low toxicity.As an imaging agent,CDs can be used for targeting imaging of Golgi apparatus.展开更多
High fluorescence quantum yield(QY),excellent fluorescence stability,and low toxicity are essential for a good cellular imaging fluorescent probe.Green-emissive carbon quantum dots(CQDs)with many advantages,such as un...High fluorescence quantum yield(QY),excellent fluorescence stability,and low toxicity are essential for a good cellular imaging fluorescent probe.Green-emissive carbon quantum dots(CQDs)with many advantages,such as unique fluorescence properties,anti-photobleaching,low toxicity,fine biocompatibility and high penetration depth in tissues,have been considered as a potential candidate in cell imaging fluorescent probes.Herein,N,S-codoped green-emissive CQDs(QY=64.03%)were synthesized by the one-step hydrothermal method,with m-phenylenediamine as the carbon and nitrogen source,and L-cysteine as the nitrogen and sulfur dopant,under the optimum condition of 200℃ reaction for 2 h.Their luminescence was found to originate from the surface state.In light of the satisfactory photobleaching resistance and the low cytotoxicity,CQDs were used as a cell imaging probe for HeLa cell imaging.The results clearly indicate that cells can be labeled with CQDs,which can not only enter the cytoplasm,but also enter the nucleus through the nuclear pore,showing their broad application prospect in the field of cell imaging.展开更多
Silver nanoparticles(Ag NPs) were successfully assembled in porous anodic alumina(AAO) templates via a green silver mirror reaction.The Ag NPs/AAO composite templates then were characterized by field emission scan...Silver nanoparticles(Ag NPs) were successfully assembled in porous anodic alumina(AAO) templates via a green silver mirror reaction.The Ag NPs/AAO composite templates then were characterized by field emission scanning electron microscopy(FESEM),energy-dispersive X-ray microanalysis(EDX),and X-ray diffraction(XRD).Furthermore,the photoluminescence(PL) properties were also investigated.Compared with the blank AAO,the PL intensity of Ag NPs/AAO templates are enhanced and the maximum enhancement is 2.58 times.Based on the local electric field enhancement effect,the theoretical values were also deduced,which are basically coincident with the experimental.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.11674234 and 11605205)the Fundamental Research Funds for the Central Universities,China(Grant No.2012017yjsy143)+4 种基金the National Key Research and Development Program of China(Grant No.2017YFA0305200)the Youth Innovation Promotion Association of Chinese Academy of Sciences(CAS)(Grant No.2015317)the Natural Science Foundation of Chongqing,China(Grant Nos.cstc2015jcyjA00021 and cstc2018jcyjAX0656)the Entrepreneurship and Innovation Support Program for Chongqing Overseas Returnees,China(Grant No.cx017134)the Fund of CAS Key Laboratory of Microscale Magnetic Resonance,China,and the Fund of CAS Key Laboratory of Quantum Information,China
文摘Pre-and post-selected(PPS) measurement, especially the weak PPS measurement, has been proved to be a useful tool for measuring extremely tiny physical parameters. However, it is difficult to retain both the attainable highest measurement sensitivity and precision with the increase of the parameter to be measured. Here, a modulated PPS measurement scheme based on coupling-strength-dependent modulation is presented with the highest sensitivity and precision retained for an arbitrary coupling strength. This idea is demonstrated by comparing the modulated PPS measurement scheme with the standard PPS measurement scheme in the case of unbalanced input meter. By using the Fisher information metric, we derive the optimal pre-and post-selected states, as well as the optimal coupling-strength-dependent modulation without any restriction on the coupling strength. We also give the specific strategy of performing the modulated PPS measurement scheme, which may promote practical application of this scheme in precision metrology.
基金National Key R&D Program of China(Grant No.2017YFA0305200)the National Natural Science Foundation of China(Grant Nos.11674234 and 11605205)+4 种基金the Natural Science Foundation of Chongqing,China(Grant Nos.cstc2015jcyjA00021 and cstc2018jcyjAX0656)Innovation Project of Sichuan University,China(Grant No.2018SCUH0021)the Youth Innovation Promotion Association,Chinese Academy of Sciences(Grant No.2015317)the Entrepreneurship and Innovation Support Program for Chongqing Overseas Returnees,China(Grant Nos.cx2017134 and cx2018040)the Fund of CAS Key Laboratory of Microscale Magnetic Resonance,and the Fund of CAS Key Laboratory of Quantum Information,China.
文摘We introduce a modified weak value that is related to the mean value of input meter variable.With the help of the modified weak value,the validity conditions for various modified versions of weak value formalism are investigated,in terms of the dependence of the pointer shift on the mean value of the input meter.The weak value formalism,often used to represent the pointer shift,with the modified weak value is of great use in simplifying calculations and giving guidance of practical experiments whenever the mean value of the input meter variable is nonzero.The simulation in a qubit system is presented and coincident well with our theoretical result.
基金supported by the National Key Research and Development Program of China (Grant No. 2017YFA0305200)the National Natural Science Foundation of China (Grant Nos. 11674234 and 11605205)+5 种基金the Natural Science Foundation of Chongqing (Grant Nos. cstc2015jcyjA00021 and cstc2018jcyjAX0656)the Innovation Project of Sichuan University (Grant No. 2018SCUH0021)the Youth Innovation Promotion Association Program of the Chinese Academy of Sciences (CAS)(Grant No. No. 2015317)the Entrepreneurship and Innovation Support Program for Chongqing Overseas Returnees (Grant Nos. cx2017134and cx2018040)the Fund of CAS Key Laboratory of Microscale Magnetic Resonancethe Fund of CAS Key Laboratory of Quantum Information。
文摘We theoretically introduce the statistical uncertainty of photon number and phase error to discuss the precision of parameters to be measured based on weak measurements. When the photon counting scheme is used, we discuss the relative accuracy of the system in the presence of phase error by using the orthogonal and nonorthogonal pre-and postselected states, respectively. When using the measurement scheme of pointer shift, we discuss the measurement accuracy in the presence of phase error, pointer resolution, and statistical uncertainty. These results give a guide way to get the smallest relative precision and deepen our understanding about weak measurement.
基金Project supported by the National Natural Science Foundation of China (Grant No. 11604227).
文摘The strong chiroptical effect is highly desirable and has a wide range of applications in biosensing, chiral catalysis,polarization tuning, and chiral photo detection. In this work, we find a simple method to enhance the reflection circular dichroism(CDR) by placing the planar anisotropic chiral metamaterials(i.e., Z-shaped PACMs) on the interface of two media(i.e., Z-PCMI) with a large refractive index difference. The maximum reflection CDR from the complex system can reach about 0.840 when the refractive index is set as ntop = 4.0 and nbottom = 1.49, which is approximately three times larger than that of placing the Z-shaped PACMs directly on the substrate(i.e., Z-PCMS). While the minimum reflection CDR is 0.157 when the refractive index is set as ntop = 1.0 and nbottom = 1.49. So we can get a large available range of reflection CDR from -0.840 to -0.157. Meanwhile, the transmission CDT remains unchanged with the refractive index ntop increment. Our in-depth research indicates that the large reflection CDR is derived from the difference of non-conversion components of the planar anisotropic chiral metamaterials’ reflection matrices. In short, we provide a simple and practical method to enhance the chiroptical effect by changing the refractive index difference between two media without having to design a complex chiral structure.
基金This work was supported by the National Natural Science Foundation of China(82172048 and U21A20378)the Natural Science Foundation of Shanxi Province(202103021223439 and 201901D111419)+4 种基金the Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(2021SX-FR010)the Shanxi Technology Innovation Center for Controlled and Sustained Release of Nano-drugs(202104010911026)the Doctoral Starting Foundation of Shanxi Province(SD2218)the Doctoral Foundation of the Second Hospital of Shanxi Medical University(202201-1)Collaborative Innovation Center of R&D molecular diagnosis,Treatment Technology and targeted drugs for cancer of Shanxi Medical University(5-2-1-A-5).
文摘The Golgi apparatus is one of the important organelles,where the final processing and packaging of cellular secretions(such as proteins)are completed.The disorder of Golgi apparatus structure and function will induce many diseases.Therefore,monitoring the morphological structure of Golgi apparatus is crucial for the diagnosis and treatment of relevant diseases.In order to achieve Golgi apparatus-targeting imaging,the strategy of targeting unit inheritance was adopted and carbon dots(CDs)with Golgi apparatus-targeting ability were synthesized by one-step hydrothermal method with L-ascorbic acid with high reactivity and reducibility as the carbon source and L-cysteine as the targeting unit.CDs have a certain amount of cysteine residues on their surface,and have excitation dependence,satisfactory fluorescence and cysteine residues stability and low toxicity.As an imaging agent,CDs can be used for targeting imaging of Golgi apparatus.
基金supported by the National Natural Science Foundation of China(Grant Nos.51972221 and 51803148)Central Government Guides Local Science and Technology Development Projects(YDZX20201400001722)+1 种基金the Shanxi Provincial Excellent Talents Science and Technology Innovation Project(201805D211001)the Natural Science Foundation of Shanxi Province(201901D211502 and 201901D211501).
文摘High fluorescence quantum yield(QY),excellent fluorescence stability,and low toxicity are essential for a good cellular imaging fluorescent probe.Green-emissive carbon quantum dots(CQDs)with many advantages,such as unique fluorescence properties,anti-photobleaching,low toxicity,fine biocompatibility and high penetration depth in tissues,have been considered as a potential candidate in cell imaging fluorescent probes.Herein,N,S-codoped green-emissive CQDs(QY=64.03%)were synthesized by the one-step hydrothermal method,with m-phenylenediamine as the carbon and nitrogen source,and L-cysteine as the nitrogen and sulfur dopant,under the optimum condition of 200℃ reaction for 2 h.Their luminescence was found to originate from the surface state.In light of the satisfactory photobleaching resistance and the low cytotoxicity,CQDs were used as a cell imaging probe for HeLa cell imaging.The results clearly indicate that cells can be labeled with CQDs,which can not only enter the cytoplasm,but also enter the nucleus through the nuclear pore,showing their broad application prospect in the field of cell imaging.
基金the National Natural Science Foundation of China (Grand Nos.60878031,J0830308)the National Basic Research Programme of China (Grant No.2006CB302902)the Natural Science Foundation of Chaohu College (Grant No.XLY-200813)
文摘Silver nanoparticles(Ag NPs) were successfully assembled in porous anodic alumina(AAO) templates via a green silver mirror reaction.The Ag NPs/AAO composite templates then were characterized by field emission scanning electron microscopy(FESEM),energy-dispersive X-ray microanalysis(EDX),and X-ray diffraction(XRD).Furthermore,the photoluminescence(PL) properties were also investigated.Compared with the blank AAO,the PL intensity of Ag NPs/AAO templates are enhanced and the maximum enhancement is 2.58 times.Based on the local electric field enhancement effect,the theoretical values were also deduced,which are basically coincident with the experimental.