Premature ovarian failure(POF)refers to the failure of ovaries which causes amenorrhea before the age of 40.It is characterized by primary or secondary amenorrhea along with elevated blood gonadotropin levels and decr...Premature ovarian failure(POF)refers to the failure of ovaries which causes amenorrhea before the age of 40.It is characterized by primary or secondary amenorrhea along with elevated blood gonadotropin levels and decreased estrogen levels with varying degrees of low estrogen symptoms such as hot flashes and sweating,facial flushing,reduced libido,and so on.Premature ovarian failure(POF)is a common endocrine disease in gynecology.The incidence of POF is increasing year by year and the affected population increasingly involves the younger-aged groups.Its etiology is complex and diverse involving many factors such as genetics,immunity,medical treatment,environment endocrine disruptors,etc.It is also affected by long-term smoking,alcohol intake,and other behaviors which damage patients9 physical and mental health.In recent years,the effects of gene therapy in restoring ovarian function and improving fertility in animal experiments have provided a new direction for POF patients.This article discusses the etiology and possible pathogenesis of POF and BRCA from various aspects as well as summarizes the recent research status and progress of new treatment methods of POF.展开更多
Huazhong University of Science and Technology has developed an experimental setup of a radio frequency(RF) driven negative hydrogen ion source,to investigate the physics of production and extraction of the H^(-)ions f...Huazhong University of Science and Technology has developed an experimental setup of a radio frequency(RF) driven negative hydrogen ion source,to investigate the physics of production and extraction of the H^(-)ions for neutral beam injection in nuclear fusion reactors.The main design parameters of the ion source are:RF power ≤40 kW;extraction voltage ≤10kV;accelerator voltage ≤20 kV.This paper gives an overview of the progress of the ion source with particular emphasis on some issues.The RF driver and source plasma are analyzed and optimized in terms of impedance matching,plasma characteristics and power coupling.In regard to the simulation analysis,a plasma model based on the particle-in-cell method and a beam trajectory model considering beam stripping loss are developed to investigate the plasma and negative ions transport inside the ion source.Furthermore,a collisional radiative model of H and H2is built for plasma optical diagnosis.展开更多
This paper describes the importance of plant quarantine to the food safety in China through cases where plant quarantine helps to effectively intercept harmful organisms for food safety and promote export and import t...This paper describes the importance of plant quarantine to the food safety in China through cases where plant quarantine helps to effectively intercept harmful organisms for food safety and promote export and import trading.It also presents the existing problems in plant quarantine work and appropriate measures.展开更多
基金by the National Natural Science Foundation of China for Young Scholars(82003865)Application research of the Science and Technology Department in Sichuan Province(21YYJC2810(2021YJ0461))Science and Technology Project of Chengdu:Key Research and Development Support Plan(2019-YF05-00250-SN).
文摘Premature ovarian failure(POF)refers to the failure of ovaries which causes amenorrhea before the age of 40.It is characterized by primary or secondary amenorrhea along with elevated blood gonadotropin levels and decreased estrogen levels with varying degrees of low estrogen symptoms such as hot flashes and sweating,facial flushing,reduced libido,and so on.Premature ovarian failure(POF)is a common endocrine disease in gynecology.The incidence of POF is increasing year by year and the affected population increasingly involves the younger-aged groups.Its etiology is complex and diverse involving many factors such as genetics,immunity,medical treatment,environment endocrine disruptors,etc.It is also affected by long-term smoking,alcohol intake,and other behaviors which damage patients9 physical and mental health.In recent years,the effects of gene therapy in restoring ovarian function and improving fertility in animal experiments have provided a new direction for POF patients.This article discusses the etiology and possible pathogenesis of POF and BRCA from various aspects as well as summarizes the recent research status and progress of new treatment methods of POF.
基金supported by the National Key R&D Program of China(No.2017YFE0300105)National Natural Science Foundation of China(Nos.11775088 and 12005074)the Fundamental Research Funds for the Central Universities,HUST(No.2021XXJS013)
文摘Huazhong University of Science and Technology has developed an experimental setup of a radio frequency(RF) driven negative hydrogen ion source,to investigate the physics of production and extraction of the H^(-)ions for neutral beam injection in nuclear fusion reactors.The main design parameters of the ion source are:RF power ≤40 kW;extraction voltage ≤10kV;accelerator voltage ≤20 kV.This paper gives an overview of the progress of the ion source with particular emphasis on some issues.The RF driver and source plasma are analyzed and optimized in terms of impedance matching,plasma characteristics and power coupling.In regard to the simulation analysis,a plasma model based on the particle-in-cell method and a beam trajectory model considering beam stripping loss are developed to investigate the plasma and negative ions transport inside the ion source.Furthermore,a collisional radiative model of H and H2is built for plasma optical diagnosis.
文摘This paper describes the importance of plant quarantine to the food safety in China through cases where plant quarantine helps to effectively intercept harmful organisms for food safety and promote export and import trading.It also presents the existing problems in plant quarantine work and appropriate measures.
