Calculation of the Two High Voltage Transmission Line Conductors’ Minimum Distance

In the design of high voltage transmission lines inevitably needed to change the arrangement of wires, and the distance between the wires directly affected by changing the arrangement of the wires. The distance between the wires is difficult to judge by experiences. Therefore, it is urgently to develop a way to accurately calculating the minimum distance between the wires when changing the arrangement between the two wires, and determine the minimum distance can meet the requirements of standards and regulations or not. Through the thinking, based on the balance equation and the space curve wire calculus method, a more accurate method of calculating the two wires in a variety of conditions the minimum spacing was derivated, and the sensitivity of the minimum distance was analysized based on the method.

Phosphatidylcholine deficiency increases ferroptosis susceptibility in the Caenorhabditis elegans germline

Ferroptosis,a regulated and iron-dependent form of cell death characterized by peroxidation of membrane phospholipids,has tremendous potential for the therapy of human diseases.The causal link between phospholipid homeostasis and ferroptosis is incompletely understood.Here,we reveal that spin-4,a previously identified regulator of the“B12-one-carbon cycle-phosphatidylcholine(PC)”pathway,sustains germline development and fertility by ensuring PC sufficiency in the nematode Caenorhabditis elegans.Mechanistically,SPIN-4 regulates lysosomal activity which is required for B12-associated PC synthesis.PC deficiency-induced sterility can be rescued by reducing the levels of polyunsaturated fatty acids,reactive oxygen species,and redox-active iron,which indicates that the sterility is mediated by germline ferroptosis.These results highlight the critical role of PC homeostasis in ferroptosis susceptibility and offer a new target for pharmacological approaches.

Preparation of Ag@AgCl-doped TiO_2/sepiolite and its photocatalytic mechanism under visible light

A cube-like Ag@Ag Cl-doped TiO_2/sepiolite(denoted Ag@Ag Cl–TiO_2/sepiolite) was successfully synthesized via a novel method. X-ray diffraction, scanning electron microscopy, energy dispersion X-ray fluorescence, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and diffuse reflectance ultraviolet–visible spectroscopy were performed to determine the structure and physicochemical properties of Ag@Ag Cl–TiO_2/sepiolite. SEM micrographs revealed that Ag@Ag Cl nanoparticles and TiO_2 film are well deposited on the surface of tube-like sepiolite. As a result, Ag@Ag Cl–TiO_2/sepiolite exhibits a red shift relative to TiO_2/sepiolite. Photocatalytic experiments demonstrated that the dosage of catalysts plays an important role during photocatalysis. The photoelectrochemical activities of Ag@Ag Cl–TiO_2/sepiolite and TiO_2/sepiolite were also investigated. Photocurrent responses confirmed that the ability of Ag@Ag Cl–TiO_2/sepiolite to separate photo-generated electron–hole pairs is stronger than that of TiO_2/sepiolite. Methylene Blue degradation is also improved under alkaline conditions and visible light irradiation because more UOH is produced by visible light excitation.This excellent catalytic ability is mainly attributed to the formed Ag nanoparticles and the Schottky barrier at the Ag/TiO_2 interface. Active species analysis indicated that UO2-and h+are implicated as active species in photocatalysis. Therefore, catalysts are excited to produce abundant electron–hole pairs after they absorb photons in photocatalysis.

Endocrine function of pheromones couples fat rationing and nutrient scarcity

Harsh environmental conditions, such as food scarcity,drought and coldness, are ubiquitous threats to most living things. During evolution, organisms have developed diverse strategies to survive such inhospitable periods (Olsen et al.,2021). Many avian species and some fish (e.g., salmon)

Reduced phosphatidylcholine synthesis suppresses the embryonic lethality of seipin deficiency

Seipin plays a vital role in lipid droplet homeostasis,and its deficiency causes congenital generalized lipodystrophy type II in humans.It is not known whether the physiological defects are all caused by cellular lipid droplet defects.Loss-of-function mutation of seip-1,the Caenorhabditis elegans seipin ortholog,causes embryonic lethality and lipid droplet abnormality.We uncover nhr-114 and spin-4 as two suppressors of seip-1 embryonic lethality.Mechanistically,nhr-114 and spin-4 act in the“B12-one-carbon cycle-phosphatidylcholine(PC)”axis,and reducing PC synthesis suppresses the embryonic lethality of seip-1 mutants.Conversely,PC deficiency enhances the lipid droplet abnormality of seip-1 mutants.The suppression of seip-1 embryonic lethality by PC reduction requires polyunsaturated fatty acid.In addition,the suppression is enhanced by the knockdown of phospholipid scramblase epg-3.Therefore,seipin and PC exhibit opposite actions in embryogenesis,while they function similarly in lipid droplet homeostasis.Our results demonstrate that seipin-mediated embryogenesis is independent of lipid droplet homeostasis.