RCT Meta-analysis on Buyang Huanwu Decoction Combined with Acupuncture and Buyang Huanwu Decoction Alone in the Treatment of Apoplectic Hemiplegia

[Objectives] To evaluate the efficacy and safety of two different treatment regimens( Buyang Huanwu Decoction combined with acupuncture and Buyang Huanwu Decoction alone) in the treatment of apoplectic hemiplegia. [Methods]Electronic databases: China Knowledge Infrastructure( CNKI),Wanfang database( Wan Fang Data),VIP database( VIP),China Biomedical Literature Database( CBM),MEDLINE,The Cochrane Library,Pubmed,Chinese Journal of Integrative Medicine,and Journal of Traditional Chinese Medicine were searched. The published randomized controlled trials( RCT) of Buyang Huanwu Decoction combined with acupuncture and Buyang Huanwu Decoction alone in the treatment of apoplectic hemiplegia were screened. The Jadad scale was used to evaluate the methodological quality of the included literature. The data was extracted and the meta-analysis was carried out with reference to the Systematic Evaluation,Meta-analysis Design and Implementation Method. [Results]A total of 8 articles were included,a total of 765 patients,and there were 8 articles with Jadad scores lower than 4 points. Meta-analysis results indicate that The experimental group of Buyang Huanwu Decoction combined with acupuncture treatment improved the comprehensive clinical efficacy OR = 3. 89,95% CI[2. 58,5. 86]( P < 0. 000 01),BI score SMD = 2. 35,95% CI[2. 04,2. 66]( P <0. 000 01) was better than the control group. [Conclusions]The treatment regimen of Buyang Huanwu Decoction combined with acupuncture can improve the daily activities of patients with apoplectic hemiplegia and improve the clinical efficacy. It is better than the treatment regimen of Buyang Huanwu Decoction alone.

Comparison of genetic impact on growth and wood traits between seedlings and clones from the same plus trees of Pinus koraiensis

To evaluate the relationships among clones and open pollinated families from the same plus trees and to select elite breeding materials,growth,and wood characteristics of 33-year-old Pinus korainsis clones and families were measured and analyzed.The results show that growth and wood characters varied significantly.The variation due to clonal effects was higher than that of family effects.The ratio of genetic to phenotypic coefficient of variation of clones in growth and wood traits was above 90%,and the repeatability of these characteristics was more than 0.8,whereas the ratio of genetic to phenotypic coefficient of variation of families was above 90%.The broad-sense heritability of all characteristics exceeded 0.4,and the narrow-sense family heritability of growth traits was less than 0.3.Growth characteristics were positively correlated with each other,but most wood properties were weakly correlated in both clones and families.Fiber length and width were positively correlated between clones and families.Using the membership function method,eleven clones and four families were selected as superior material for improved diameter growth and wood production,and two families from clonal and open-pollinated trees showed consistently better performance.Generally,selection of the best clones is an effective alternative to deployment of families as the repeatability estimates from clonal trees were higher than narrow-sense heritability estimates from open pollinated families.The results provide valuable insight for improving P.koraiensis breeding programs and subsequent genetic improvement.