Northeast China is an important base for grain production,dominated by rain-fed agriculture that relies on green water.However,in the context of global climate change,rising regional temperatures,changing precipitatio...Northeast China is an important base for grain production,dominated by rain-fed agriculture that relies on green water.However,in the context of global climate change,rising regional temperatures,changing precipitation patterns,and increasing drought frequency pose threats and challenges to agricultural green water security.This study provides a detailed assessment of the spatiotemporal characteristics and development trends of green water security risks in the Northeast region under the base period(2001-2020)and the future(2031-2090)climate change scenarios(SSP245 and SSP585)using the green water scarcity(GWS)index based on raster-scale crop spatial distribution data,Delta downscaling bias-corrected ERA5 data,and CMIP6 multimodal data.During the base period,the green water risk-free zone for dry crops is mainly distributed in the center and east of the Northeast region(72.4% of the total area),the low-risk zone is primarily located in the center(14.0%),and the medium-risk(8.3%)and high-risk(5.3%)zones are mostly in the west.Under SSP245 and SSP585 future climate change scenarios,the green water security risk shows an overall expansion from the west to the center and east,with the low-risk zone increasing to 21.6% and 23.8%,the medium-risk zone increasing to 16.0% and 17.9%,and the high-risk zone increasing to 6.9% and 6.8%,respectively.Considering dry crops with GWS greater than 0.1 as in need of irrigation,the irrigated area increases from 27.6%(base period)to 44.5%(SSP245)and 48.6%(SSP585),with corresponding increases in irrigation water requirement(IWR)of 4.64 and 5.92 billion m~3,respectively,which further exacerbates conflicts between supply and demand of agricultural water resources.In response to agricultural green water security risks,coping strategies such as evapotranspiration(ET)-based water resource management for dry crops and deficit irrigation are proposed.The results of this study can provide scientific basis and decision support for the development of Northeast irrigated agriculture and the construction planning of the national water network.展开更多
Metamaterials are widely used in electromagnetic radiation and camouflage for their flexible wavefront manipulation and polarization over a broad spectrum ranging from microwaves to optics.However,multispectral compat...Metamaterials are widely used in electromagnetic radiation and camouflage for their flexible wavefront manipulation and polarization over a broad spectrum ranging from microwaves to optics.However,multispectral compatible camouflage faces significant challenges due to tremendous scale differences of unit cells and desired radiative properties in various spectral regimes.This study assembles a micron-scale infrared emitter,a millimeter-scale microwave absorber,and a metal reflector to propose a hierarchical metamaterial that reduces microwave scattering and reflects low-infrared waves.As a proof of concept,laser etching micro-manufactures an upper infrared shielding layer with a periodic metal pattern.At the same time,bottom square frustum metastructure composites are fabricated and optimized based on genetic algorithms.Under the normal incidence transverse electromagnetic wave with a 90°azimuth angle,the hierarchical strategy and infrared unit create an asymmetric electric field distribution of local near-field coupling,which is conducive to generating additional resonance for broadening the absorption bandwidth.Experiments verify the multispectral camouflage,which shows a high absorption efficiency of more than 90%,ranging from 3.6 to 6.2 and from 8.4 to 18 GHz with a total thickness of 4.05 mm(0.049λmax).Due to the non-reflection of surrounding thermal signals in the infrared 2-22μm region,low-infrared emissivity(0.29)metamaterials can adapt to various thermal backgrounds.This methodology can provide a novel route for fabricating multispectral camouflage devices.展开更多
Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent ne...Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent need to develop inexpensive and efficient animal vaccines to prevent and control coronavirus disease 2019(COVID-19)in animals.Rabies virus(RABV)is another important zoonotic pathogen that infects almost all warmblooded animals and poses a great public health threat.The present study constructed two recombinant chimeric viruses expressing the S1 and RBD proteins of the SARS-CoV-2 Wuhan01 strain based on a reverse genetic system of the RABV SRV9 strain and evaluated their immunogenicity in mice,cats and dogs.The results showed that both inactivated recombinant viruses induced durable neutralizing antibodies against SARS-CoV-2 and RABV and a strong cellular immune response in mice.Notably,inactivated SRV-nCoV-RBD induced earlier antibody production than SRV-nCoV-S1,which was maintained at high levels for longer periods.Inactivated SRV-nCoV-RBD induced neutralizing antibodies against both SARS-CoV-2 and RABV in cats and dogs,with a relatively broadspectrum cross-neutralization capability against the SARS-CoV-2 pseudoviruses including Alpha,Beta,Gamma,Delta,and Omicron,showing potential to be used as a safe bivalent vaccine candidate against COVID-19 and rabies in animals.展开更多
Although inactivated vaccines against rabies have the advantage of high safety,effective protection against rabies virus(RABV)infection often requires multiple,high-dose immunization.Incorporating a molecular adjuvant...Although inactivated vaccines against rabies have the advantage of high safety,effective protection against rabies virus(RABV)infection often requires multiple,high-dose immunization.Incorporating a molecular adjuvant into the viral particles has been found to be a useful strategy to promote the immune effectiveness of inactivated vaccines.In this study,we constructed a recombinant virus,rCVS11-LTB,which chimerically expresses a molecular adjuvant heat-labile enterotoxin B subunit(LTB)protein on the surface of the RABV particles.Immunogenicity in vivo was found to be promoted by rCVS11-LTB through the activation of dendritic cells(DCs).Our results demonstrated that inactivated rCVS11-LTB was able to induce higher levels of virusneutralizing antibodies(VNAs)in both mice and dogs than the parent virus rCVS11,to enhance the cellular immune response and T cell immune memory in mice,and was also able to provide 100%protection in mice from lethal doses of rabies virus,indicating its potential as a safe and effective inactivated rabies vaccine candidate.展开更多
We investigated 1-μm multimode fiber laser based on carbon nanotubes,where multiple typical pulse states were observed,including Q-switched,Q-switched mode-locked,and spatiotemporal mode-locked pulses.Particularly,st...We investigated 1-μm multimode fiber laser based on carbon nanotubes,where multiple typical pulse states were observed,including Q-switched,Q-switched mode-locked,and spatiotemporal mode-locked pulses.Particularly,stable spatiotemporal mode-locking was realized with a low threshold,where the pulse duration was 37 ps and the wavelength was centred at 1060.5 nm.Moreover,both the high signal to noise and long-term operation stability proved the reliability of the mode-locked laser.Furthermore,the evolution of the spatiotemporal mode-locked pulses in the cavity was also simulated and discussed.This work exhibits the flexible outputs of spatiotemporal phenomena in multimode lasers based on nanomaterials,providing more possibilities for the development of high-dimensional nonlinear dynamics.展开更多
基金supported by the Strategic Priority Research Program(Class A)of the Chinese Academy of Sciences(Grant No.XDA28020501)the Strategic Research and Consulting Program of the Chinese Academy of Engineering(Grant No.JL2023-17)。
文摘Northeast China is an important base for grain production,dominated by rain-fed agriculture that relies on green water.However,in the context of global climate change,rising regional temperatures,changing precipitation patterns,and increasing drought frequency pose threats and challenges to agricultural green water security.This study provides a detailed assessment of the spatiotemporal characteristics and development trends of green water security risks in the Northeast region under the base period(2001-2020)and the future(2031-2090)climate change scenarios(SSP245 and SSP585)using the green water scarcity(GWS)index based on raster-scale crop spatial distribution data,Delta downscaling bias-corrected ERA5 data,and CMIP6 multimodal data.During the base period,the green water risk-free zone for dry crops is mainly distributed in the center and east of the Northeast region(72.4% of the total area),the low-risk zone is primarily located in the center(14.0%),and the medium-risk(8.3%)and high-risk(5.3%)zones are mostly in the west.Under SSP245 and SSP585 future climate change scenarios,the green water security risk shows an overall expansion from the west to the center and east,with the low-risk zone increasing to 21.6% and 23.8%,the medium-risk zone increasing to 16.0% and 17.9%,and the high-risk zone increasing to 6.9% and 6.8%,respectively.Considering dry crops with GWS greater than 0.1 as in need of irrigation,the irrigated area increases from 27.6%(base period)to 44.5%(SSP245)and 48.6%(SSP585),with corresponding increases in irrigation water requirement(IWR)of 4.64 and 5.92 billion m~3,respectively,which further exacerbates conflicts between supply and demand of agricultural water resources.In response to agricultural green water security risks,coping strategies such as evapotranspiration(ET)-based water resource management for dry crops and deficit irrigation are proposed.The results of this study can provide scientific basis and decision support for the development of Northeast irrigated agriculture and the construction planning of the national water network.
基金supported by the National Natural Science Foundation of China(Nos.52103334,52071053,and U1704253)China Postdoctoral Science Foundation(Nos.2020M680946,2020M670748)the Fundamental Research Funds for the Central Universities(No.DUT20GF111).
文摘Metamaterials are widely used in electromagnetic radiation and camouflage for their flexible wavefront manipulation and polarization over a broad spectrum ranging from microwaves to optics.However,multispectral compatible camouflage faces significant challenges due to tremendous scale differences of unit cells and desired radiative properties in various spectral regimes.This study assembles a micron-scale infrared emitter,a millimeter-scale microwave absorber,and a metal reflector to propose a hierarchical metamaterial that reduces microwave scattering and reflects low-infrared waves.As a proof of concept,laser etching micro-manufactures an upper infrared shielding layer with a periodic metal pattern.At the same time,bottom square frustum metastructure composites are fabricated and optimized based on genetic algorithms.Under the normal incidence transverse electromagnetic wave with a 90°azimuth angle,the hierarchical strategy and infrared unit create an asymmetric electric field distribution of local near-field coupling,which is conducive to generating additional resonance for broadening the absorption bandwidth.Experiments verify the multispectral camouflage,which shows a high absorption efficiency of more than 90%,ranging from 3.6 to 6.2 and from 8.4 to 18 GHz with a total thickness of 4.05 mm(0.049λmax).Due to the non-reflection of surrounding thermal signals in the infrared 2-22μm region,low-infrared emissivity(0.29)metamaterials can adapt to various thermal backgrounds.This methodology can provide a novel route for fabricating multispectral camouflage devices.
基金funded by the National Key Research and Development Program of China(grant No.2021YFC2600202)the National Natural Science Foundation of China(grant numbers 31872487).
文摘Many studies suggest that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can infect various animals and transmit among animals,and even to humans,posing a threat to humans and animals.There is an urgent need to develop inexpensive and efficient animal vaccines to prevent and control coronavirus disease 2019(COVID-19)in animals.Rabies virus(RABV)is another important zoonotic pathogen that infects almost all warmblooded animals and poses a great public health threat.The present study constructed two recombinant chimeric viruses expressing the S1 and RBD proteins of the SARS-CoV-2 Wuhan01 strain based on a reverse genetic system of the RABV SRV9 strain and evaluated their immunogenicity in mice,cats and dogs.The results showed that both inactivated recombinant viruses induced durable neutralizing antibodies against SARS-CoV-2 and RABV and a strong cellular immune response in mice.Notably,inactivated SRV-nCoV-RBD induced earlier antibody production than SRV-nCoV-S1,which was maintained at high levels for longer periods.Inactivated SRV-nCoV-RBD induced neutralizing antibodies against both SARS-CoV-2 and RABV in cats and dogs,with a relatively broadspectrum cross-neutralization capability against the SARS-CoV-2 pseudoviruses including Alpha,Beta,Gamma,Delta,and Omicron,showing potential to be used as a safe bivalent vaccine candidate against COVID-19 and rabies in animals.
基金the National Key Research and Development Program of China(No.2022YFD1800100).
文摘Although inactivated vaccines against rabies have the advantage of high safety,effective protection against rabies virus(RABV)infection often requires multiple,high-dose immunization.Incorporating a molecular adjuvant into the viral particles has been found to be a useful strategy to promote the immune effectiveness of inactivated vaccines.In this study,we constructed a recombinant virus,rCVS11-LTB,which chimerically expresses a molecular adjuvant heat-labile enterotoxin B subunit(LTB)protein on the surface of the RABV particles.Immunogenicity in vivo was found to be promoted by rCVS11-LTB through the activation of dendritic cells(DCs).Our results demonstrated that inactivated rCVS11-LTB was able to induce higher levels of virusneutralizing antibodies(VNAs)in both mice and dogs than the parent virus rCVS11,to enhance the cellular immune response and T cell immune memory in mice,and was also able to provide 100%protection in mice from lethal doses of rabies virus,indicating its potential as a safe and effective inactivated rabies vaccine candidate.
基金supported by the National Natural Science Foundation of China(Grant No.62071016)the State Key Laboratory of Advanced Optical Communication Systems Networks,Chinathe Academic Excellence Foundation of BUAA for PhD Students.
文摘We investigated 1-μm multimode fiber laser based on carbon nanotubes,where multiple typical pulse states were observed,including Q-switched,Q-switched mode-locked,and spatiotemporal mode-locked pulses.Particularly,stable spatiotemporal mode-locking was realized with a low threshold,where the pulse duration was 37 ps and the wavelength was centred at 1060.5 nm.Moreover,both the high signal to noise and long-term operation stability proved the reliability of the mode-locked laser.Furthermore,the evolution of the spatiotemporal mode-locked pulses in the cavity was also simulated and discussed.This work exhibits the flexible outputs of spatiotemporal phenomena in multimode lasers based on nanomaterials,providing more possibilities for the development of high-dimensional nonlinear dynamics.