Systematic control of grain boundary densities in various platinum(Pt)nanostructures was achieved by specific peptide-assisted assembly and coagulation of nanocrystals.A positive quadratic correlation was observed bet...Systematic control of grain boundary densities in various platinum(Pt)nanostructures was achieved by specific peptide-assisted assembly and coagulation of nanocrystals.A positive quadratic correlation was observed between the oxygen reduction reaction(ORR)specific activities of the Pt nanostructures and the grain boundary densities on their surfaces.Compared to commercial Pt/C,the grain-boundary-rich strain-free Pt ultrathin nanoplates demonstrated a 15.5 times higher specific activity and a 13.7 times higher mass activity.Simulation studies suggested that the specific activity of ORR was proportional to the resident number and the resident time of oxygen on the catalyst surface,both of which correlate positively with grain boundary density,leading to improved ORR activities.展开更多
Evidence has shown that some dietary polyphenols(flavonoids,phenolic acids,tannins,lignans,saponins,terpenoids,etc.)can alleviate alcoholic liver disease(ALD).Raspberries,the fourth most significant fruit worldwide,co...Evidence has shown that some dietary polyphenols(flavonoids,phenolic acids,tannins,lignans,saponins,terpenoids,etc.)can alleviate alcoholic liver disease(ALD).Raspberries,the fourth most significant fruit worldwide,comprise a particular phytochemical profile encompassing ellagitannins and anthocyanins and exert many biological activities.In contrast to Chinese liquor(named Baijiu in China),the effect of two kinds of raspberry wines(fermentation and soaking types)on the liver is poorly understood.This study aimed to evaluate the effect of the two types of raspberry wines on the liver in a mouse model.The results showed that the livers of mice treated with raspberry wines produced less malondialdehyde,hepatic function markers,and proinflammatory cytokines,and less lipid accumulation in the serum and liver was also found compared to the mice treated with Baijiu.The activities of antioxidant markers in the liver from the raspberry wine supplementation group were higher than those receiving Baijiu.This study demonstrated that raspberry wines provoked more minor liver injury than Baijiu.The degree of liver damage caused by soaked raspberry wine was lower than that induced by fermented raspberry wine.展开更多
基金E.Z.and Y.H.acknowledge the Electron Imaging Center of Nanomachines at University of California,Los Angeles for TEM support.Y.H.acknowledges support from the Office of Naval Research under grant number N000141812491National Science Foundation DMREF 1437263.S.W.and H.H.acknowledge support by the National Science Foundation(DMREF 1623947,CBET 1530790,OAC 1931587,and CMMI 1940335)+1 种基金The allocation of computational resources is acknowledged at the Argonne Leadership Computing Facility,which is a DOE Office of Science User Facility supported under contract DE-AC02-06CH11357,and at the Summit supercomputer supported by the National Science Foundation(ACI-1532235 and ACI-1532236)The authors declare no competing financial interests.Use of beamline ISS 8-ID of the National Synchrotron Light Source(NSLS)II was supported by the NSLS-II,Brookhaven National Laboratory,under U.S.DOE Contract No.DE-SC0012704.
文摘Systematic control of grain boundary densities in various platinum(Pt)nanostructures was achieved by specific peptide-assisted assembly and coagulation of nanocrystals.A positive quadratic correlation was observed between the oxygen reduction reaction(ORR)specific activities of the Pt nanostructures and the grain boundary densities on their surfaces.Compared to commercial Pt/C,the grain-boundary-rich strain-free Pt ultrathin nanoplates demonstrated a 15.5 times higher specific activity and a 13.7 times higher mass activity.Simulation studies suggested that the specific activity of ORR was proportional to the resident number and the resident time of oxygen on the catalyst surface,both of which correlate positively with grain boundary density,leading to improved ORR activities.
基金funded by the Deep Process and Functional Food Development of Daylily and Astragalus(No.201904710611637).
文摘Evidence has shown that some dietary polyphenols(flavonoids,phenolic acids,tannins,lignans,saponins,terpenoids,etc.)can alleviate alcoholic liver disease(ALD).Raspberries,the fourth most significant fruit worldwide,comprise a particular phytochemical profile encompassing ellagitannins and anthocyanins and exert many biological activities.In contrast to Chinese liquor(named Baijiu in China),the effect of two kinds of raspberry wines(fermentation and soaking types)on the liver is poorly understood.This study aimed to evaluate the effect of the two types of raspberry wines on the liver in a mouse model.The results showed that the livers of mice treated with raspberry wines produced less malondialdehyde,hepatic function markers,and proinflammatory cytokines,and less lipid accumulation in the serum and liver was also found compared to the mice treated with Baijiu.The activities of antioxidant markers in the liver from the raspberry wine supplementation group were higher than those receiving Baijiu.This study demonstrated that raspberry wines provoked more minor liver injury than Baijiu.The degree of liver damage caused by soaked raspberry wine was lower than that induced by fermented raspberry wine.
