We introduce a new class of the chirped Airy–Gaussian vortex electron plasma(CAiGVEP)wave which constitutes the exact and continuous transition modes between the chirped Airy vortex and the chirped Gaussian vortex el...We introduce a new class of the chirped Airy–Gaussian vortex electron plasma(CAiGVEP)wave which constitutes the exact and continuous transition modes between the chirped Airy vortex and the chirped Gaussian vortex electron plasma wave.The intensity,the phase,and the angular momentum density flow of the CAiGVEP wave are discussed under different distribution factors and different chirp modes.展开更多
Anesthesia risks for surgery of airway foreign body removal are very high. A safe way to anaesthetize the patients is important. This report presented a case of an infant with a foreign body in the subglottic area, wh...Anesthesia risks for surgery of airway foreign body removal are very high. A safe way to anaesthetize the patients is important. This report presented a case of an infant with a foreign body in the subglottic area, which was ultimately removed by rigid laryngoscopy under spontaneous respiratory using dexmedetomidine (DEX). A loading dose of DEX 4 μg·kg-1 and sevoflurane 2 MAC could provide adequate depth of anesthesia during inserting the rigid bronchoscopy, and DEX 3 μg·kg-1·h-1 was suitable for the maintance of anethesia with spontaneous respiratory. We considered that the maintenance of spontaneous respiration is one of the key points.展开更多
Antifreeze protein(AFP)can inhibit the growth of ice crystals to protect organisms from freezing damage,and demonstrates broad application prospects in food industry.Antifreeze peptides(AFPP)are specifi c peptides wit...Antifreeze protein(AFP)can inhibit the growth of ice crystals to protect organisms from freezing damage,and demonstrates broad application prospects in food industry.Antifreeze peptides(AFPP)are specifi c peptides with functional domains showing antifreeze activity in AFP.Bioinformatics-based molecular simulation technology can more accurately explain the properties and mechanisms of biological macromolecules.Therefore,the binding stability of antifreeze peptides and antifreeze proteins(AFP(P))to ice and the molecular-scale growth kinetics of ice were analyzed by molecular simulation,which can make up for the limitations of experimental technology.This review concludes the molecular simulation-based research in the inhibition’s study of AFP(P)on ice growth,including sequence prediction,structure construction,molecular docking and molecular dynamics(MD)studies of AFP(P)on ice applications in growth inhibition.Finally,the review prospects the future direction of designing new antifreeze biomimetic materials through molecular simulation and machine learning.The information presented in this paper will help enrich our understanding of AFPP.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11775083 and 11374108)the Science and Technology Program of Guangzhou City(Grant No.2019050001)the Special Funds for the Cultivation of Guangdong College Students’Scientific and Technological Innovation(Grant Nos.pdjh2020a0149 and pdjh2019a0127).
文摘We introduce a new class of the chirped Airy–Gaussian vortex electron plasma(CAiGVEP)wave which constitutes the exact and continuous transition modes between the chirped Airy vortex and the chirped Gaussian vortex electron plasma wave.The intensity,the phase,and the angular momentum density flow of the CAiGVEP wave are discussed under different distribution factors and different chirp modes.
文摘Anesthesia risks for surgery of airway foreign body removal are very high. A safe way to anaesthetize the patients is important. This report presented a case of an infant with a foreign body in the subglottic area, which was ultimately removed by rigid laryngoscopy under spontaneous respiratory using dexmedetomidine (DEX). A loading dose of DEX 4 μg·kg-1 and sevoflurane 2 MAC could provide adequate depth of anesthesia during inserting the rigid bronchoscopy, and DEX 3 μg·kg-1·h-1 was suitable for the maintance of anethesia with spontaneous respiratory. We considered that the maintenance of spontaneous respiration is one of the key points.
基金This work was supported by Natural Science Foundation of China(U1905202)Fujian Major Project of Provincial Science&Technology Hall of China(2020NZ010008)Xiamen Ocean and Fishery Development Special Fund Project(21CZP006HJ04).
文摘Antifreeze protein(AFP)can inhibit the growth of ice crystals to protect organisms from freezing damage,and demonstrates broad application prospects in food industry.Antifreeze peptides(AFPP)are specifi c peptides with functional domains showing antifreeze activity in AFP.Bioinformatics-based molecular simulation technology can more accurately explain the properties and mechanisms of biological macromolecules.Therefore,the binding stability of antifreeze peptides and antifreeze proteins(AFP(P))to ice and the molecular-scale growth kinetics of ice were analyzed by molecular simulation,which can make up for the limitations of experimental technology.This review concludes the molecular simulation-based research in the inhibition’s study of AFP(P)on ice growth,including sequence prediction,structure construction,molecular docking and molecular dynamics(MD)studies of AFP(P)on ice applications in growth inhibition.Finally,the review prospects the future direction of designing new antifreeze biomimetic materials through molecular simulation and machine learning.The information presented in this paper will help enrich our understanding of AFPP.