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Probing the intriguing frictional behavior of hydrogels during alternative sliding velocity cycles 被引量:1
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作者 Yiming ZHAO Gang YI +6 位作者 Jiuyu CUI Ziqian ZHAO Yonggan YAN Luxing WEI jinlong shao Hongbo ZENG Jun HUANG 《Friction》 SCIE EI CAS CSCD 2023年第12期2329-2341,共13页
Understanding the friction behavior of hydrogels is critical for the long-term stability of hydrogelrelated bioengineering applications.Instead of maintaining a constant sliding velocity,the actual motion of bio-compo... Understanding the friction behavior of hydrogels is critical for the long-term stability of hydrogelrelated bioengineering applications.Instead of maintaining a constant sliding velocity,the actual motion of bio-components(e.g.,articular cartilage and cornea)often changes abruptly.Therefore,it is important to study the frictional properties of hydrogels serving under various sliding velocities.In this work,an unexpected low friction regime(friction coefficientμ<10^(-4) at 1.05×10^(-3) rad/s)was observed when the polyacrylamide hydrogel was rotated against a glass substrate under alternative sliding velocity cycles.Interestingly,compared with the friction coefficients under constant sliding velocities,the measuredμdecreased significantly when the sliding velocity changed abruptly from high speeds(e.g.,105 rad/s)to low speeds(e.g.,1.05×10^(-3) rad/s).In addition,μexhibited a downswing trend at low speeds after experiencing more alternative sliding velocity cycles:the measuredμat 1.05 rad/s decreased from 2×10^(-2) to 3×10^(-3) after 10 friction cycles.It is found that the combined effect of hydration film and polymer network deformation determines the lubrication and drag reduction of hydrogels when the sliding velocity changes abruptly.The observed extremely low friction during alternative sliding velocity cycles can be applied to reduce friction at contacted interfaces.This work provides new insights into the fundamental understanding of the lubrication behaviors and mechanisms of hydrogels,with useful implications for the hydration lubrication related engineering applications such as artificial cartilage. 展开更多
关键词 hydrogel friction alternative sliding velocity ultra-low friction coefficient drag reduction
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牙龈退缩根面覆盖治疗1例
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作者 吕春旭 邵金龙 +1 位作者 于洋 葛少华 《中国口腔医学继续教育杂志》 2023年第1期58-64,共7页
目的牙龈退缩常常导致根面敏感、菌斑控制不良和牙龈美学等问题,影响患者的口腔健康和颜面美观。本病例采用根面覆盖术治疗牙龈退缩,以改善患者牙齿敏感问题。诊治经过:手术采用冠向复位瓣联合结缔组织移植瓣双层技术治疗退缩类型(reces... 目的牙龈退缩常常导致根面敏感、菌斑控制不良和牙龈美学等问题,影响患者的口腔健康和颜面美观。本病例采用根面覆盖术治疗牙龈退缩,以改善患者牙齿敏感问题。诊治经过:手术采用冠向复位瓣联合结缔组织移植瓣双层技术治疗退缩类型(recession type,RT)为1类的牙龈退缩。结果术后2周,受区龈缘略水肿;术后12个月复诊,龈缘位置趋于稳定,根面覆盖率达100%,角化龈宽度及临床附着水平增加。患者无牙齿敏感、系带牵拉和瘢痕形成等不适症状,牙龈美学效果良好。结论冠向复位瓣联合结缔组织移植瓣双层技术治疗RT 1类牙龈退缩效果良好,不仅能够获得完全根面覆盖、牙龈美学效果良好,而且增加了术区角化牙龈的宽度和临床附着水平。 展开更多
关键词 牙龈退缩 结缔组织移植瓣 冠向复位瓣 根面覆盖 麦氏龈缘突
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Dimethyloxallyl glycine/nanosilicates-loaded osteogenic/angiogenic difunctional fibrous structure for functional periodontal tissue regeneration 被引量:8
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作者 Lingling Shang Ziqi Liu +4 位作者 Baojin Ma jinlong shao Bing Wang Chenxi Ma shaohua Ge 《Bioactive Materials》 SCIE 2021年第4期1175-1188,共14页
The coupled process of osteogenesis-angiogenesis plays a crucial role in periodontal tissue regeneration.Although various cytokines or chemokines have been widely applied in periodontal in situ tissue engineering,most... The coupled process of osteogenesis-angiogenesis plays a crucial role in periodontal tissue regeneration.Although various cytokines or chemokines have been widely applied in periodontal in situ tissue engineering,most of them are macromolecular proteins with the drawbacks of short effective half-life,poor stability and high cost,which constrain their clinical translation.Our study aimed to develop a difunctional structure for periodontal tissue regeneration by incorporating an angiogenic small molecule,dimethyloxalylglycine(DMOG),and an osteoinductive inorganic nanomaterial,nanosilicate(nSi)into poly(lactic-co-glycolic acid)(PLGA)fibers by electrospinning.The physiochemical properties of DMOG/nSi-PLGA fibrous membranes were characterized.Thereafter,the effect of DMOG/nSi-PLGA membranes on periodontal tissue regeneration was evaluated by detecting osteogenic and angiogenic differentiation potential of periodontal ligament stem cells(PDLSCs)in vitro.Additionally,the fibrous membranes were transplanted into rat periodontal defects,and tissue regeneration was assessed with histological evaluation,micro-computed tomography(micro-CT),and immunohistochemical analysis.DMOG/nSi-PLGA membranes possessed preferable mechanical property and biocompatibility.PDLSCs seeded on the DMOG/nSi-PLGA membranes showed up-regulated expression of osteogenic and angiogenic markers,higher alkaline phosphatase(ALP)activity,and more tube formation in comparison with single application.Further,in vivo study showed that the DMOG/nSi-PLGA membranes promoted recruitment of CD90+/CD34stromal cells,induced angiogenesis and osteogenesis,and regenerated cementum-ligament-bone complex in periodontal defects.Consequently,the combination of DMOG and nSi exerted admirable effects on periodontal tissue regeneration.DMOG/nSi-PLGA fibrous membranes could enhance and orchestrate osteogenesis-angiogenesis,and may have the potential to be translated as an effective scaffold in periodontal tissue engineering. 展开更多
关键词 Periodontal tissue regeneration DMOG Nanosilicate Osteogenesis-angiogenesis coupling ELECTROSPINNING
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