Stereoelectroencephalography(SEEG)has been widely used in the presurgical evaluation of patients with medically intractable epilepsy.In the past,SEEG was commonly used as a method for mapping and localizing the epilep...Stereoelectroencephalography(SEEG)has been widely used in the presurgical evaluation of patients with medically intractable epilepsy.In the past,SEEG was commonly used as a method for mapping and localizing the epileptogenic zone(EZ).Since 2004,several studies have been conducted to examine the effectiveness of SEEG-guided radiofrequency thermocoagulation(RF-TC)in treating refractory epilepsy.However,the seizure-free and responder rates varied greatly across studies.We aimed to analyze the outcome of 56 patients who were treated with SEEG-guided RF-TC to evaluate the effectiveness of this treatment.SEEG-guided RF-TC can be considered as a treatment for refractory epilepsy.However,due to its limited efficacy,SEEG-guided RF-TC might be regarded as a temporary treatment performed under SEEG rather than a promising treatment for refractory epilepsy.展开更多
Epileptic spasm(ES)is one of the most common types of seizures in children.It is primarily characterized by brief axial contractions lasting less than 2 s and recurring in short clusters.It usually occurs in children ...Epileptic spasm(ES)is one of the most common types of seizures in children.It is primarily characterized by brief axial contractions lasting less than 2 s and recurring in short clusters.It usually occurs in children of 3 to 12 months of age,although it can also occur after the age of 1 year.In general,children with ES develop other symptoms of epilepsy,such as tonic,tonic-clonic,or focal seizures,after 3 to 5 years of age.ES in children is often damaging and usually results in developmental regression.First-line treatments for spasm seizures include adrenocorticotropic hormone(ACTH)and vigabatrin.However,many patients fail to respond to these medications,and continued to have spasms associated with progressive neurodevelopmental degeneration.Therefore,it is important to consider whether children with drug resistance meet surgical indications to consider surgical treatment in such conditions.In this study,we reviewed and summarized the importance of preoperative evaluation in order to provide surgical options for treatment of children with ES.展开更多
文摘Stereoelectroencephalography(SEEG)has been widely used in the presurgical evaluation of patients with medically intractable epilepsy.In the past,SEEG was commonly used as a method for mapping and localizing the epileptogenic zone(EZ).Since 2004,several studies have been conducted to examine the effectiveness of SEEG-guided radiofrequency thermocoagulation(RF-TC)in treating refractory epilepsy.However,the seizure-free and responder rates varied greatly across studies.We aimed to analyze the outcome of 56 patients who were treated with SEEG-guided RF-TC to evaluate the effectiveness of this treatment.SEEG-guided RF-TC can be considered as a treatment for refractory epilepsy.However,due to its limited efficacy,SEEG-guided RF-TC might be regarded as a temporary treatment performed under SEEG rather than a promising treatment for refractory epilepsy.
文摘Epileptic spasm(ES)is one of the most common types of seizures in children.It is primarily characterized by brief axial contractions lasting less than 2 s and recurring in short clusters.It usually occurs in children of 3 to 12 months of age,although it can also occur after the age of 1 year.In general,children with ES develop other symptoms of epilepsy,such as tonic,tonic-clonic,or focal seizures,after 3 to 5 years of age.ES in children is often damaging and usually results in developmental regression.First-line treatments for spasm seizures include adrenocorticotropic hormone(ACTH)and vigabatrin.However,many patients fail to respond to these medications,and continued to have spasms associated with progressive neurodevelopmental degeneration.Therefore,it is important to consider whether children with drug resistance meet surgical indications to consider surgical treatment in such conditions.In this study,we reviewed and summarized the importance of preoperative evaluation in order to provide surgical options for treatment of children with ES.
