OBJECTIVE： To identify global research trends in the use of stem cell transplantation to treat epilepsy. DATA RETRIEVAL： We performed a bibliometric analysis of studies on the use of stem cell transplantation to tre...OBJECTIVE： To identify global research trends in the use of stem cell transplantation to treat epilepsy. DATA RETRIEVAL： We performed a bibliometric analysis of studies on the use of stem cell transplantation to treat epilepsy during 2002–2011, retrieved from Web of Science, using the key words epilepsy or epileptic or epilepticus or seizure and ＂stem cell＂. SELECTION CRITERIA： Inclusion criteria： （a） peer-reviewed published articles on the use of stem cell transplantation to treat epilepsy indexed in Web of Science; （b） original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. MAIN OUTCOME MEASURES： （a） Annual publication output; （b） type of publication; （c） publication by research field; （d） publication by journal; （e） publication by author; （f） publication by country and institution; （g） publications by institution in China; （h） most-cited papers; and （i） papers published by Chinese authors or institutions. RESULTS： A total of 460 publications on the use of stem cell transplantation to treat epilepsy were retrieved from Web of Science, 2002–2011. The number of publications gradually increased over the 10-year study period. Articles and reviews constituted the major types of publications. More than half of the studies were in the field of neuroscience/neurology. The most prolific journals for this topic were Epilepsia, Bone Marrow Transplantation, and Journal of Neuroscience. Of the 460 publications, almost half came from American authors and institutions; relatively few papers were published by Chinese authors or institutions. CONCLUSION： Literature on stem cell transplantation for epilepsy includes many reports of basic research, but few of clinical trials or treatments. Exact effects are not yet evaluated. Epilepsy rehabilitation is a long-term, complex, and comprehensive system engineering. With advances in medical development, some effective medical, social and educational measures are needed to facilitate patient’s treatment and training and accelerate the recovery of life ability, learning ability and social adaptability to the largest extent to improve patient’s quality of life.展开更多
Achievement of steady and reliable super-low friction at the steel/steel contact interface,one of the most tribological systems applied for mechanical moving parts,is of importance for prolonging machine lifetime and ...Achievement of steady and reliable super-low friction at the steel/steel contact interface,one of the most tribological systems applied for mechanical moving parts,is of importance for prolonging machine lifetime and reducing energy consumption.Here we reported that the superlubricity performance of the steel/steel sliding interface lubricated with tiny amounts of diketone solution strongly depends on the oxygen content in surrounding environment.The increase of oxygen not only significantly shortens the initial running-in time but also further reduces the stable coefficient of friction in superlubricity stage due to the enhancement of tribochemical reactions.On the one hand,more severe oxidation wear occurring at higher oxygen content facilitates material removal of the contact interface,lowering the contact pressure and the corresponding initial friction.On the other hand,the growth of iron ions during the shear process in high oxygen environment promotes the formation of chelate which acted as an effective lubricated film chemisorbed at the steel/steel friction interface to further lower the interfacial friction.The results provide a new opportunity to further optimize the tribological performance of diketone superlubricity system,especially towards the lubrication of mechanical engineering materials.展开更多
Graphene is a promising material as a lubricant additive for reducing friction and wear.Here,a dispersing method which combines chemical modification of graphene by octadecylamine and dicyclohexylcarbodiimide with a k...Graphene is a promising material as a lubricant additive for reducing friction and wear.Here,a dispersing method which combines chemical modification of graphene by octadecylamine and dicyclohexylcarbodiimide with a kind of effective dispersant has been successfully developed to achieve the remarkable dispersion stability of graphene in base oil.The stable dispersion time of modified graphene(0.5 wt%)with dispersant(1 wt%)in PAO-6 could be up to about 120 days,which was the longest time reported so far.At the same time,the lubricant exhibits a significant improvement of tribological performance for a steel ball to plate tribo-system with a normal load of 2 N.The coefficient of friction between sliding surfaces was~0.10 and the depth of wear track on plate was~21 nm,which decreased by about 44%and 90%when compared to pure PAO-6,respectively.Furthermore,the analysis of the lubricating mechanisms in regard to the sliding-induced formation of nanostructured tribo-film has been contacted by using Raman spectra and TEM.展开更多
This study achieved water‐based superlubricity with the lubrication of H_3PO_4 solution in vacuum(highest vacuum degree <10–4 torr) for the first time by performing a pre‐running process in air before running in...This study achieved water‐based superlubricity with the lubrication of H_3PO_4 solution in vacuum(highest vacuum degree <10–4 torr) for the first time by performing a pre‐running process in air before running in vacuum. The stable water‐based superlubricity was sustainable in vacuum(0.02 torr) for 14 h until the test was stopped by the user for non‐experimental factor. A further analysis suggested that the superlubricity may be attributed to the phosphoric acid–water network formed in air, which can efficiently lock water molecules in the liquid lubricating film even in vacuum owing to the strong hydrogen bond interaction. Such capability to lock water is strongly affected by the strength of hydrogen bond and environmental conditions. The realization of water‐based superlubricity with H_3PO_4 solution in vacuum can lead to its application in space environment.展开更多
文摘OBJECTIVE： To identify global research trends in the use of stem cell transplantation to treat epilepsy. DATA RETRIEVAL： We performed a bibliometric analysis of studies on the use of stem cell transplantation to treat epilepsy during 2002–2011, retrieved from Web of Science, using the key words epilepsy or epileptic or epilepticus or seizure and ＂stem cell＂. SELECTION CRITERIA： Inclusion criteria： （a） peer-reviewed published articles on the use of stem cell transplantation to treat epilepsy indexed in Web of Science; （b） original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. MAIN OUTCOME MEASURES： （a） Annual publication output; （b） type of publication; （c） publication by research field; （d） publication by journal; （e） publication by author; （f） publication by country and institution; （g） publications by institution in China; （h） most-cited papers; and （i） papers published by Chinese authors or institutions. RESULTS： A total of 460 publications on the use of stem cell transplantation to treat epilepsy were retrieved from Web of Science, 2002–2011. The number of publications gradually increased over the 10-year study period. Articles and reviews constituted the major types of publications. More than half of the studies were in the field of neuroscience/neurology. The most prolific journals for this topic were Epilepsia, Bone Marrow Transplantation, and Journal of Neuroscience. Of the 460 publications, almost half came from American authors and institutions; relatively few papers were published by Chinese authors or institutions. CONCLUSION： Literature on stem cell transplantation for epilepsy includes many reports of basic research, but few of clinical trials or treatments. Exact effects are not yet evaluated. Epilepsy rehabilitation is a long-term, complex, and comprehensive system engineering. With advances in medical development, some effective medical, social and educational measures are needed to facilitate patient’s treatment and training and accelerate the recovery of life ability, learning ability and social adaptability to the largest extent to improve patient’s quality of life.
基金grateful for the financial support from the National Natural Science Foundation of China(51875486 and 52122507)Sichuan Science and Technology Program(2021YFSY0017)the Fundamental Research Funds for the Central Universities(2682021ZTPY095).
文摘Achievement of steady and reliable super-low friction at the steel/steel contact interface,one of the most tribological systems applied for mechanical moving parts,is of importance for prolonging machine lifetime and reducing energy consumption.Here we reported that the superlubricity performance of the steel/steel sliding interface lubricated with tiny amounts of diketone solution strongly depends on the oxygen content in surrounding environment.The increase of oxygen not only significantly shortens the initial running-in time but also further reduces the stable coefficient of friction in superlubricity stage due to the enhancement of tribochemical reactions.On the one hand,more severe oxidation wear occurring at higher oxygen content facilitates material removal of the contact interface,lowering the contact pressure and the corresponding initial friction.On the other hand,the growth of iron ions during the shear process in high oxygen environment promotes the formation of chelate which acted as an effective lubricated film chemisorbed at the steel/steel friction interface to further lower the interfacial friction.The results provide a new opportunity to further optimize the tribological performance of diketone superlubricity system,especially towards the lubrication of mechanical engineering materials.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51527901 and 51335005)。
文摘Graphene is a promising material as a lubricant additive for reducing friction and wear.Here,a dispersing method which combines chemical modification of graphene by octadecylamine and dicyclohexylcarbodiimide with a kind of effective dispersant has been successfully developed to achieve the remarkable dispersion stability of graphene in base oil.The stable dispersion time of modified graphene(0.5 wt%)with dispersant(1 wt%)in PAO-6 could be up to about 120 days,which was the longest time reported so far.At the same time,the lubricant exhibits a significant improvement of tribological performance for a steel ball to plate tribo-system with a normal load of 2 N.The coefficient of friction between sliding surfaces was~0.10 and the depth of wear track on plate was~21 nm,which decreased by about 44%and 90%when compared to pure PAO-6,respectively.Furthermore,the analysis of the lubricating mechanisms in regard to the sliding-induced formation of nanostructured tribo-film has been contacted by using Raman spectra and TEM.
基金financial support from the National Natural Science Foundation of China (Nos.51527901,51405256)Self-developed Project of State Key Laboratory of Traction Power (No.2017TPL_Z02)
文摘This study achieved water‐based superlubricity with the lubrication of H_3PO_4 solution in vacuum(highest vacuum degree <10–4 torr) for the first time by performing a pre‐running process in air before running in vacuum. The stable water‐based superlubricity was sustainable in vacuum(0.02 torr) for 14 h until the test was stopped by the user for non‐experimental factor. A further analysis suggested that the superlubricity may be attributed to the phosphoric acid–water network formed in air, which can efficiently lock water molecules in the liquid lubricating film even in vacuum owing to the strong hydrogen bond interaction. Such capability to lock water is strongly affected by the strength of hydrogen bond and environmental conditions. The realization of water‐based superlubricity with H_3PO_4 solution in vacuum can lead to its application in space environment.
