Tumor chemoprevention and treatment are two approaches aimed at improving the survival of patients with cancers.An ideal anti-tumor drug is that which not only kills tumor cells but also alleviates tumor-causing risk ...Tumor chemoprevention and treatment are two approaches aimed at improving the survival of patients with cancers.An ideal anti-tumor drug is that which not only kills tumor cells but also alleviates tumor-causing risk factors,such as precancerous lesions,and prevents tumor recurrence.Chinese herbal monomers are considered to be ideal treatment agents due to their multi-target effects.Astragaloside has been shown to possess tumor chemoprevention,direct anti-tumor,and chemotherapeutic drug sensitization effects.In this paper,we review the effects of astragaloside on tumor prevention and treatment and provide directions for further research.展开更多
Hepatocellular carcinoma(HCC)is the most common type of primary hepatocellular carcinoma(PHC).Early diagnosis of HCC remains the key to improve the prognosis.In recent years,with the promotion of the concept of precis...Hepatocellular carcinoma(HCC)is the most common type of primary hepatocellular carcinoma(PHC).Early diagnosis of HCC remains the key to improve the prognosis.In recent years,with the promotion of the concept of precision medicine and more in-depth analysis of the biological mechanism underlying HCC,new diagnostic methods,including emerging serum markers,liquid biopsies,molecular diagnosis,and advances in imaging(novel contrast agents and radiomics),have emerged one after another.Herein,we reviewed and analyzed scientific advances in the early diagnosis of HCC and discussed their application and shortcomings.This review aimed to provide a reference for scientific research and clinical practice of HCC.展开更多
基金Natural Science Foundation of China(Nos.81902484,82002809)China Postdoctoral Science Foundation(No.2020M670864)+3 种基金Jilin Province young health scientist training program(No.2020Q017)Medical and Health Talents Project of Jilin Province(Nos.2020SCZT039,2020SCZT097)Youth Support Project of Jilin Association for Science and Technology(No.202028)Jilin Province Science and Technology Development Plan(No.20210204028YY)
文摘Tumor chemoprevention and treatment are two approaches aimed at improving the survival of patients with cancers.An ideal anti-tumor drug is that which not only kills tumor cells but also alleviates tumor-causing risk factors,such as precancerous lesions,and prevents tumor recurrence.Chinese herbal monomers are considered to be ideal treatment agents due to their multi-target effects.Astragaloside has been shown to possess tumor chemoprevention,direct anti-tumor,and chemotherapeutic drug sensitization effects.In this paper,we review the effects of astragaloside on tumor prevention and treatment and provide directions for further research.
基金Natural Science Foundation of China(No.81902484)China Postdoctoral Science Foundation(No.2020M670864)+2 种基金Medical and Health Talents Project of Jilin Province(Nos.2019SCZT003,2020SCZT096)Youth Support Project of Jilin Association for Science and Technology(No.202028)Project of Hepatobiliary and Pancreatic Disease Translational Medicine Platform Construction(No.2017F009)
文摘Hepatocellular carcinoma(HCC)is the most common type of primary hepatocellular carcinoma(PHC).Early diagnosis of HCC remains the key to improve the prognosis.In recent years,with the promotion of the concept of precision medicine and more in-depth analysis of the biological mechanism underlying HCC,new diagnostic methods,including emerging serum markers,liquid biopsies,molecular diagnosis,and advances in imaging(novel contrast agents and radiomics),have emerged one after another.Herein,we reviewed and analyzed scientific advances in the early diagnosis of HCC and discussed their application and shortcomings.This review aimed to provide a reference for scientific research and clinical practice of HCC.
