Background: The Unified Parkinson’s Disease Rating Scale is the most commonly used scale in the clinical study of Parkinson’s disease. However, it may fail to capture the essence of physical impairment in patients w...Background: The Unified Parkinson’s Disease Rating Scale is the most commonly used scale in the clinical study of Parkinson’s disease. However, it may fail to capture the essence of physical impairment in patients with Parkinson’s disease and thus limit responsiveness of care-givers, patients, and/or clinicians as to increasing physical disability. This study sought to compare subjective measures of physical disability in Parkinson’s disease to an objective, accurate, and proven measure of physical function-gait speed. Methods: Eighty-eight individuals with early to moderate stage Parkinson’s disease were evaluated on the Unified Parkinson’s Disease Rating Scale, the Parkinson’s disease Questionnaire 39 and during five 8 meter walking trials. Spearman correlations coefficients were used to determine the association among all variables of interest. Results: The findings demonstrate that only a fair to moderate relationship between objectively measured gait speed and physical function as measured subjectively by the clinical rating scale and as evaluated by the patients during self report. Conclusions: The results of this study suggest that commonly utilized measures of physical function in Parkinson’s disease are not highly correlated with gait speed. Because gait speed is demonstrated as a dependable proxy for physical function, the results of this study may provide a rational for the use of gait speed to provide a more accurate picture of physical function in patients with Parkinson’s disease.展开更多
按照普渡大学(Purdue University)校长小米奇·丹尼尔斯(Mitch Daniels Jr.)的话来说,普渡是一所“鼓励提高人口密度”的学校。这所位于印第安纳州西拉斐特市的大学目前有在校生逾4.4万人,人数比他在2013年接任校长时增加了25%。普...按照普渡大学(Purdue University)校长小米奇·丹尼尔斯(Mitch Daniels Jr.)的话来说,普渡是一所“鼓励提高人口密度”的学校。这所位于印第安纳州西拉斐特市的大学目前有在校生逾4.4万人,人数比他在2013年接任校长时增加了25%。普渡面向州内学生的学费一直保持在1万美元之内,而且食宿费用低于其他任何一家“十大联盟”院校。该校的足球场能容纳6万人,剧院比纽约的无线电城音乐厅(Radio City Music Hall)还要大。展开更多
文摘Background: The Unified Parkinson’s Disease Rating Scale is the most commonly used scale in the clinical study of Parkinson’s disease. However, it may fail to capture the essence of physical impairment in patients with Parkinson’s disease and thus limit responsiveness of care-givers, patients, and/or clinicians as to increasing physical disability. This study sought to compare subjective measures of physical disability in Parkinson’s disease to an objective, accurate, and proven measure of physical function-gait speed. Methods: Eighty-eight individuals with early to moderate stage Parkinson’s disease were evaluated on the Unified Parkinson’s Disease Rating Scale, the Parkinson’s disease Questionnaire 39 and during five 8 meter walking trials. Spearman correlations coefficients were used to determine the association among all variables of interest. Results: The findings demonstrate that only a fair to moderate relationship between objectively measured gait speed and physical function as measured subjectively by the clinical rating scale and as evaluated by the patients during self report. Conclusions: The results of this study suggest that commonly utilized measures of physical function in Parkinson’s disease are not highly correlated with gait speed. Because gait speed is demonstrated as a dependable proxy for physical function, the results of this study may provide a rational for the use of gait speed to provide a more accurate picture of physical function in patients with Parkinson’s disease.
文摘按照普渡大学(Purdue University)校长小米奇·丹尼尔斯(Mitch Daniels Jr.)的话来说,普渡是一所“鼓励提高人口密度”的学校。这所位于印第安纳州西拉斐特市的大学目前有在校生逾4.4万人,人数比他在2013年接任校长时增加了25%。普渡面向州内学生的学费一直保持在1万美元之内,而且食宿费用低于其他任何一家“十大联盟”院校。该校的足球场能容纳6万人,剧院比纽约的无线电城音乐厅(Radio City Music Hall)还要大。
