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China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design 被引量:13
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作者 Rachel P Dreyer Xi Li +12 位作者 Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick a Masoudi john a spertus Harlan M Krumholz Li-Xin Jiang 《Chinese Medical Journal》 SCIE CAS CSCD 2016年第1期72-80,共9页
Background: Despite the rapid growth in the incidence of acute myocardial infarction (AMI) in China, there is limited information about patients' experiences after AMI hospitalization, especially on long-tern1 adv... Background: Despite the rapid growth in the incidence of acute myocardial infarction (AMI) in China, there is limited information about patients' experiences after AMI hospitalization, especially on long-tern1 adverse events and patient-reported outcomes (PROs). Methods: The China Patient-centered Evaluative Assessment of Cardiac Events (PEACE)-Prospective AMI Study will enroll 4000 consecutive AM I patients from 53 diverse hospitals across China and follow them longitudinally for 12 months to docunlent their treatment, recovery, and outcomes. Details of patients' medical history, treatment, and in-hospital outcomes are abstracted from medical charts. Comprehensive baseline interviews are being conducted to characterize patient demographics, risk factors, presentation, and healthcare utilization. As part of these interviews, validated instruments are administered to measure PROs, including quality of life, symptoms, mood, cognition, and sexual activity. Follow-up interviews, measuring PROs, medication adherence, risk factor control, and collecting hospitalization events are conducted at 1, 6, and 12 months after discharge. Supporting documents for potential outcomes are collected for adjudication by clinicians at the National Coordinating Center. Blood and urine samples are also obtained at baseline, 1 - and 12-month follow-up. In addition, we are conducting a survey of participating hospitals to characterize their organizational characteristics. Conclusion: The China PEACE-Prospective AMI study will be uniquely positioned to generate new information regarding patient's experiences and outcomes alter AMI in China and seiwe as a foundation for quality improveinent activities. 展开更多
关键词 Acute Myocardial Infarction Outcomes Research Patient-reported Outcome Measures Prospective Cohort
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稳定性冠心病患者对选择性经皮冠状动脉介入治疗的理解差异:横断面研究
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作者 Faraz Kureshi NIH T-32 Philip G Jones +4 位作者 Donna M Buchanan Mouin S abdallah john a spertus 袁建松 乔树宾 《英国医学杂志中文版》 2015年第1期4-4,共1页
目的评价稳定性冠心病患者对于选择性经皮冠状动脉介入治疗(PCI)紧迫性和受益的理解程度,并评估各治疗中心和提供者之间的差异。
关键词 冠状动脉疾病 介入治疗 横断面 稳定性
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中国急性心肌梗死患者教育程度与预后的关联分析
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作者 Xiqian Huo Rohan Khera +14 位作者 Lihua Zhang Jeph Herrin Xueke Bai Qianying Wang Yuan Lu Khurram Nasir Shuang Hu Jing Li Xi Li Xin Zheng Frederick a Masoudi john a spertus Harlan M Krumholz Lixin Jiang 《英国医学杂志中文版》 2019年第4期243-243,共1页
目的中国是人口多样化、教育程度差异很大的国家,然而教育程度与我国急性心肌梗死(AMI)患者预后的相关性仍不清楚。本研究旨在探索AMI患者的教育程度与预后的相关性,以期进一步指导未来健康医疗干预的方向。方法研究基于China PEACE前瞻... 目的中国是人口多样化、教育程度差异很大的国家,然而教育程度与我国急性心肌梗死(AMI)患者预后的相关性仍不清楚。本研究旨在探索AMI患者的教育程度与预后的相关性,以期进一步指导未来健康医疗干预的方向。方法研究基于China PEACE前瞻性AMI研究的数据,共纳入来自中国53家医院的3 369名连续入选的AMI患者,并根据其接受教育的程度分为高(高中、大学及研究生)、中(初中学位)、低(小学及小学以下)3个不同水平。采用生存模型分析不同教育程度与AMI后1年严重心血管病不良事件(MACE)发生率和全因病死率的关系,并校正了人口统计学和心血管危险因素等差异的影响。结果研究人群的中位年龄为61(52~69)岁,23.2%为女性,33.3%为高学历水平,32.4%为中等学历水平,34.3%为低学历水平。与高中、大学或研究生学历相比,小学或小学以下学历患者的1年MACE发生率更高(危害比2.41, 95%可信区间1.72~3.37),全因病死率也显著增高(危害比3.09, 95%可信区间1.69~5.65)。在校正人口统计学及共病因素后,教育程度与1年全因病死率的关联减弱(危害比1.41, 95%可信区间0.74~2.69, P=0.30),但教育程度与AMI后1年MACE的关联仍有统计学意义,且学历低的患者的不良事件发生风险是学历高者的近1.7倍(调整危害比1.68, 95%可信区间1.18~2.41, P=0.004)。结论在中国AMI住院患者人群中,教育程度较低的患者在AMI发病1年内发生不良心血管事件和全因死亡的风险更高。将来对AMI患者的健康干预应根据其教育程度的不同,有针对性地完善出院后的宣教和护理,以期改善患者预后。临床试验注册号NCT01624909。 展开更多
关键词 急性心肌梗死 患者教育 预后 中国 人口统计学 学历水平 心血管危险因素 不良心血管事件
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