The theory of evolution was advanced by Darwin in 1859, prior to Mendel’s experiments demonstrating the particulate nature of inheritance. The modern synthesis was formulated in the early 1940s, well before the conce...The theory of evolution was advanced by Darwin in 1859, prior to Mendel’s experiments demonstrating the particulate nature of inheritance. The modern synthesis was formulated in the early 1940s, well before the concept of coded information was understood. This paper outlines four mathematical challenges to the modern synthesis, which are based on current understanding of the proposed mechanisms of evolutionary change within the constraints of experimental molecular biology.展开更多
文摘The theory of evolution was advanced by Darwin in 1859, prior to Mendel’s experiments demonstrating the particulate nature of inheritance. The modern synthesis was formulated in the early 1940s, well before the concept of coded information was understood. This paper outlines four mathematical challenges to the modern synthesis, which are based on current understanding of the proposed mechanisms of evolutionary change within the constraints of experimental molecular biology.