历史能力对家庭医学的未来发展至关重要，反思家庭医学历史是探讨其未来的首要环节。本期为您带来《Journal of the American Board of Family Medicine》杂志的最新家庭医学动态——回到未来：家庭医学未来项目（FFM）历史的反思；从...历史能力对家庭医学的未来发展至关重要，反思家庭医学历史是探讨其未来的首要环节。本期为您带来《Journal of the American Board of Family Medicine》杂志的最新家庭医学动态——回到未来：家庭医学未来项目（FFM）历史的反思；从多代人的角度对FFM历史和家庭医学过去十年演变进行反思，旨在引发代际对话。此类代际对话能够使年长者与年轻人共享智慧，同时以后代之眼呈现学科历史，期望对我国的全科医学未来发展规划有所启发。展开更多
ObjectiveRecent randomised controlled trials underestimated the incidence of genitourinary (GU) complications occurring more than 5 years following pelvic radiotherapy. This study aimed to determine the burden of trea...ObjectiveRecent randomised controlled trials underestimated the incidence of genitourinary (GU) complications occurring more than 5 years following pelvic radiotherapy. This study aimed to determine the burden of treatment at a single institution from late GU complications after pelvic radiotherapy.MethodsA prospective study of all presentations for GU complications following pelvic radiotherapy at a tertiary urology department between November 2018 and November 2019 was performed. Subgroup analyses was performed on patients with prostate cancer (PCa) with late toxicity to compare patient demographics, radiotherapy, complications, and management factors.ResultsThere were 117 hospital encounters involving 46 patients with a 56.4% repeat encounter rate. Patients with PCa were the predominant group (n=39, 84.8%). External beam radiotherapy was the most common treatment modality (n=41, 89.1%). The median time from radiotherapy to encounter was 8 (range 0–23) years. Radiation-induced haemorrhagic cystitis was the most common presentation (n=70, 59.8%). Forty-four (42.7%) encounters for GU toxicity were managed operatively and 33 (32.0%) involved a non-operative procedure. Nine patients required packed red cell transfusion, with a total of 154 units transfused. Patients with PCa who presented with late GU toxicity had higher median Radiotherapy Oncology Group grades (p=0.020), proportion of emergency admissions (p=0.047), and frequency of clot urinary retention (p<0.001).ConclusionThere is a high burden of elective and emergency urology workload attributed to late pelvic radiation toxicity. Late GU toxicity occurring ≥5 years after radiotherapy is common and often more severe.展开更多
文摘历史能力对家庭医学的未来发展至关重要，反思家庭医学历史是探讨其未来的首要环节。本期为您带来《Journal of the American Board of Family Medicine》杂志的最新家庭医学动态——回到未来：家庭医学未来项目（FFM）历史的反思；从多代人的角度对FFM历史和家庭医学过去十年演变进行反思，旨在引发代际对话。此类代际对话能够使年长者与年轻人共享智慧，同时以后代之眼呈现学科历史，期望对我国的全科医学未来发展规划有所启发。
文摘ObjectiveRecent randomised controlled trials underestimated the incidence of genitourinary (GU) complications occurring more than 5 years following pelvic radiotherapy. This study aimed to determine the burden of treatment at a single institution from late GU complications after pelvic radiotherapy.MethodsA prospective study of all presentations for GU complications following pelvic radiotherapy at a tertiary urology department between November 2018 and November 2019 was performed. Subgroup analyses was performed on patients with prostate cancer (PCa) with late toxicity to compare patient demographics, radiotherapy, complications, and management factors.ResultsThere were 117 hospital encounters involving 46 patients with a 56.4% repeat encounter rate. Patients with PCa were the predominant group (n=39, 84.8%). External beam radiotherapy was the most common treatment modality (n=41, 89.1%). The median time from radiotherapy to encounter was 8 (range 0–23) years. Radiation-induced haemorrhagic cystitis was the most common presentation (n=70, 59.8%). Forty-four (42.7%) encounters for GU toxicity were managed operatively and 33 (32.0%) involved a non-operative procedure. Nine patients required packed red cell transfusion, with a total of 154 units transfused. Patients with PCa who presented with late GU toxicity had higher median Radiotherapy Oncology Group grades (p=0.020), proportion of emergency admissions (p=0.047), and frequency of clot urinary retention (p<0.001).ConclusionThere is a high burden of elective and emergency urology workload attributed to late pelvic radiation toxicity. Late GU toxicity occurring ≥5 years after radiotherapy is common and often more severe.
