On 21 December of 2019,four lower respiratory tract samples were collected from patients with pneumonia of unknown cause in Wuhan,China[1].This disease was later diagnosed as a coronavirus disease.The World Health Org...On 21 December of 2019,four lower respiratory tract samples were collected from patients with pneumonia of unknown cause in Wuhan,China[1].This disease was later diagnosed as a coronavirus disease.The World Health Organization(WHO)named the coronavirus disease as COVID-19 on 11 February and declared a pandemic on 11 March 2020.The COVID-19 is a previously unknown disease with no tools available for pharmaceutical management at the early stage of its outbreak.展开更多
The reproduction number,R,is the average number of secondary infectious cases produced by one infectious case during a disease outbreak[1].When a population is totally susceptible,R becomes the basic reproduction numb...The reproduction number,R,is the average number of secondary infectious cases produced by one infectious case during a disease outbreak[1].When a population is totally susceptible,R becomes the basic reproduction number,R_(0).It is a key parameter regulating the transmission dynamics of a pandemic[2].R_(0)provides an indication of whether the introduction of disease will result in a localized burnout or signal the beginning of a pandemic that could move through all geographic scales[3].展开更多
基金supported by the National Natural Science Foundation of China(41930647,41421001,41590844)Strategic Priority Research Program(A)of Chinese Academy of Sciences(XDA20030203)+1 种基金Innovation Project of State Key Laboratory of Resources and Environment Information System(O88RA600YA)Biodiversity Investigation,Observation and Assessment Program(2019-2023)of the Ministry of Ecology and Environment of China。
文摘On 21 December of 2019,four lower respiratory tract samples were collected from patients with pneumonia of unknown cause in Wuhan,China[1].This disease was later diagnosed as a coronavirus disease.The World Health Organization(WHO)named the coronavirus disease as COVID-19 on 11 February and declared a pandemic on 11 March 2020.The COVID-19 is a previously unknown disease with no tools available for pharmaceutical management at the early stage of its outbreak.
基金the National Natural Science Foundation of China(41421001,41930647,and 41590844)the Strategic Priority Research Program(A)of the Chinese Academy of Sciences(XDA20030203)+1 种基金the Innovation Project of State Key Laboratory of Resources and Environment Information System(O88RA600YA)the Biodiversity Investigation,Observation and Assessment Program(2019-2023)of the Ministry of Ecology and Environment of China。
文摘The reproduction number,R,is the average number of secondary infectious cases produced by one infectious case during a disease outbreak[1].When a population is totally susceptible,R becomes the basic reproduction number,R_(0).It is a key parameter regulating the transmission dynamics of a pandemic[2].R_(0)provides an indication of whether the introduction of disease will result in a localized burnout or signal the beginning of a pandemic that could move through all geographic scales[3].
