The axoneme of the human sperm has a very similar ultrastructure to motile cilia,the"9+2"structure,comprising nine peripheral double microtubules plus two central pairs(Nicastro et al.,2006;Ishikawa,2017).A ...The axoneme of the human sperm has a very similar ultrastructure to motile cilia,the"9+2"structure,comprising nine peripheral double microtubules plus two central pairs(Nicastro et al.,2006;Ishikawa,2017).A proteomics analysis identified more than700 proteins exclusively in the sperm tail,and abnormal expression of related genes can cause male infertility with multiple morphological abnormalities of flagella(MMAF),including absent,coiled,short,and irregular-caliber flagella(Baker et al.,2013;Coutton et al.,2015).展开更多
基金supported by the National Natural Science Foundation of China(81971441,31625015,and 31521003)Foundation of the Education Department of Anhui Province(KJ2019A0286)Key R&D program of Anhui Province(202004j07020032)
文摘The axoneme of the human sperm has a very similar ultrastructure to motile cilia,the"9+2"structure,comprising nine peripheral double microtubules plus two central pairs(Nicastro et al.,2006;Ishikawa,2017).A proteomics analysis identified more than700 proteins exclusively in the sperm tail,and abnormal expression of related genes can cause male infertility with multiple morphological abnormalities of flagella(MMAF),including absent,coiled,short,and irregular-caliber flagella(Baker et al.,2013;Coutton et al.,2015).
