Cardiovascular diseases are the main cause of morbidity and mortality in the world, and obesity and the metabolic syndrome are risk factors for its development. One of the therapies to reduce cardiovascular risk is th...Cardiovascular diseases are the main cause of morbidity and mortality in the world, and obesity and the metabolic syndrome are risk factors for its development. One of the therapies to reduce cardiovascular risk is the use of polyunsaturated fatty acids. In Brazil, a source of such acid is the oil extracted from the fat of the capybara. The objective of this work is to study the effects of the capybara oil on lipid and glucose metabolism, as well as its effects on the adipose tissue and cardiac remodeling. We assessed the effects of capybara oil treatment on body mass, lipid and carbohydrate metabolism, systolic blood pressure, adipose tissue and cardiac remodeling, and performed an ultrastructural evaluation of the myocardium in C57Bl/6 mice treated with high-fat diet. Treatment with capybara oil reduced total cholesterol and triglyceride levels, systolic blood pressure, visceral and subcutaneous adipose tissue, and adipocyte diameter. In addition, cardiac remodeling was attenuated, preserving cardiomyocytes, increasing vascularization, reducing cardiomyocyte hypertrophy and the extracellular matrix, and preserving the morphological integrity of mitochondria. Capybara oil has several beneficial effects on the cardiovascular and metabolic system, and further studies are needed to better understand its role in the prevention or treatment of cardiovascular diseases.展开更多
Following the worldwide trend of developing heavy metal free materials, dental implants aren’t out of this tendency. Over the years, a number of techniques to condition the surface of dental implants have been design...Following the worldwide trend of developing heavy metal free materials, dental implants aren’t out of this tendency. Over the years, a number of techniques to condition the surface of dental implants have been designed and used such as oxide blasting, however the scientific medical community has been concerned about the use of these heavy metals which leads us to investigate and develop new conditioning techniques. The aim of the study was the analysis of the Systhex<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>®</sup></span></span> implant surface in automatic system for the treatment of the surface with acid, where we can identify the surfaces purity level, pore size, deepness and especially the roughness proportionated by the technology of acid conditioning on the titanium surfaces of degree IV dental implants. We conclude that the automatic conditioning of acid attack promoted cleanliness, homogeneity and ideal roughness for the osseointegration process.展开更多
文摘Cardiovascular diseases are the main cause of morbidity and mortality in the world, and obesity and the metabolic syndrome are risk factors for its development. One of the therapies to reduce cardiovascular risk is the use of polyunsaturated fatty acids. In Brazil, a source of such acid is the oil extracted from the fat of the capybara. The objective of this work is to study the effects of the capybara oil on lipid and glucose metabolism, as well as its effects on the adipose tissue and cardiac remodeling. We assessed the effects of capybara oil treatment on body mass, lipid and carbohydrate metabolism, systolic blood pressure, adipose tissue and cardiac remodeling, and performed an ultrastructural evaluation of the myocardium in C57Bl/6 mice treated with high-fat diet. Treatment with capybara oil reduced total cholesterol and triglyceride levels, systolic blood pressure, visceral and subcutaneous adipose tissue, and adipocyte diameter. In addition, cardiac remodeling was attenuated, preserving cardiomyocytes, increasing vascularization, reducing cardiomyocyte hypertrophy and the extracellular matrix, and preserving the morphological integrity of mitochondria. Capybara oil has several beneficial effects on the cardiovascular and metabolic system, and further studies are needed to better understand its role in the prevention or treatment of cardiovascular diseases.
文摘Following the worldwide trend of developing heavy metal free materials, dental implants aren’t out of this tendency. Over the years, a number of techniques to condition the surface of dental implants have been designed and used such as oxide blasting, however the scientific medical community has been concerned about the use of these heavy metals which leads us to investigate and develop new conditioning techniques. The aim of the study was the analysis of the Systhex<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>®</sup></span></span> implant surface in automatic system for the treatment of the surface with acid, where we can identify the surfaces purity level, pore size, deepness and especially the roughness proportionated by the technology of acid conditioning on the titanium surfaces of degree IV dental implants. We conclude that the automatic conditioning of acid attack promoted cleanliness, homogeneity and ideal roughness for the osseointegration process.