BACKGROUND Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)causes coronavirus disease 2019(COVID-19).This disease was declared a worldwide health problem with the characteristics of a pandemic.Most patients...BACKGROUND Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)causes coronavirus disease 2019(COVID-19).This disease was declared a worldwide health problem with the characteristics of a pandemic.Most patients have mild symptoms and a good prognosis.Information on the evolution and prognosis of COVID-19 in solid organ recipients is scarce.CASE SUMMARY We describe two patients who underwent liver transplantation with a positive test result for detection of the viral sequence for COVID-19,using reversetranscription polymerase chain reaction(RT-PCR),immediately before transplantation.The patients showed good evolution in the postoperative period,without signs of graft dysfunction.The immunosuppressive therapy was not modified.Both patients were discharged for subsequent outpatient follow-up.CONCLUSION In conclusion,it is expected that the experience at this center can be used as an example,aimed at the continuation of transplantations by other services and,thus,the morbidity and mortality of patients with liver disease on the transplantation waiting list can be reduced.Transplant centers must be able to readjust daily to the evolution of the COVID-19 pandemic.展开更多
文摘BACKGROUND Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)causes coronavirus disease 2019(COVID-19).This disease was declared a worldwide health problem with the characteristics of a pandemic.Most patients have mild symptoms and a good prognosis.Information on the evolution and prognosis of COVID-19 in solid organ recipients is scarce.CASE SUMMARY We describe two patients who underwent liver transplantation with a positive test result for detection of the viral sequence for COVID-19,using reversetranscription polymerase chain reaction(RT-PCR),immediately before transplantation.The patients showed good evolution in the postoperative period,without signs of graft dysfunction.The immunosuppressive therapy was not modified.Both patients were discharged for subsequent outpatient follow-up.CONCLUSION In conclusion,it is expected that the experience at this center can be used as an example,aimed at the continuation of transplantations by other services and,thus,the morbidity and mortality of patients with liver disease on the transplantation waiting list can be reduced.Transplant centers must be able to readjust daily to the evolution of the COVID-19 pandemic.
