Background Studies investigating health-related quality of life(HRQoL)in youth with perinatally acquired HIV(PHIV+)are scarce.This study aimed to compare HRQoL of PHIV+to sociodemographic-matched youth not living with...Background Studies investigating health-related quality of life(HRQoL)in youth with perinatally acquired HIV(PHIV+)are scarce.This study aimed to compare HRQoL of PHIV+to sociodemographic-matched youth not living with HIV(HIV-),Spanish general youth population,and to explore associations between sociodemographic variables,drug consumption,and HRQoL.Methods PHIV+youth were randomly selected from CoRISpe database(Cohort of the Spanish Pediatric HIV Network).HRQoL was evaluated by SF-12v2.Results Thirty-nine PHIV+youth(mean age:23.36 years,SD=3.83)and thirty-nine HIV-youth(mean age:22.97 years,SD=3.80)participated in this study.PHIV+obtained lower scores in SF-12 physical health subscale(PCS)than HIV-(P=0.001)and Spanish general youth population(P=0.006).PHIV+had lower scores on the mental health subscale(MCS)than the Spanish general youth population(P<0.001).PHIV+who were at school obtained better scores than those were not at school.PHIV+youth who had used cocaine and cannabis had lower scores in MCS(P=0.002).Conclusions There is a need for HRQoL management in the associated medical follow-up.展开更多
基金supported by Instituto de Salud Carlos III[FIS 15/00694]which is co-funded by Fondo Europeo de Desarrollo Regional(FEDER):Una manera de hacer EuropaTS has been funded by a 2014 Research Fellowship Award from the European Society of Pediatric Infectious Diseases(ESPID)and the Spanish Ministry of Science and Innovation(Instituto de Salud Carlos IIII,Contratos Juan Rodes,JRl6/00021)and Feder-FFE+2 种基金CV was funded by Comunidad de Madrid and fondos FEDER(Ayudas para la contratacion de ayudantes de Investigacion y tecnicos de laboratorio/Orden 2524/2016,de 1 de agosto,BOCM num.188,de 8 de agosto de 2016)CoRISpeS-Cohorte de Madrid(Pediatric HIV Infection National Cohort)is included in the AIDS Research Network(RED-RIS)since 2008,and funded by Instituto de Salud Carlos III(RD16/0025/0019)ISCIII-Subdireccion General de Evaluacion and el Fondo Europeo de Desarrollo Regional(FEDER)[RIS_EPICLIN_11_2019,RIS-EPICLIN-12/2012 and RIS-EPICLIN-06/2013]
文摘Background Studies investigating health-related quality of life(HRQoL)in youth with perinatally acquired HIV(PHIV+)are scarce.This study aimed to compare HRQoL of PHIV+to sociodemographic-matched youth not living with HIV(HIV-),Spanish general youth population,and to explore associations between sociodemographic variables,drug consumption,and HRQoL.Methods PHIV+youth were randomly selected from CoRISpe database(Cohort of the Spanish Pediatric HIV Network).HRQoL was evaluated by SF-12v2.Results Thirty-nine PHIV+youth(mean age:23.36 years,SD=3.83)and thirty-nine HIV-youth(mean age:22.97 years,SD=3.80)participated in this study.PHIV+obtained lower scores in SF-12 physical health subscale(PCS)than HIV-(P=0.001)and Spanish general youth population(P=0.006).PHIV+had lower scores on the mental health subscale(MCS)than the Spanish general youth population(P<0.001).PHIV+who were at school obtained better scores than those were not at school.PHIV+youth who had used cocaine and cannabis had lower scores in MCS(P=0.002).Conclusions There is a need for HRQoL management in the associated medical follow-up.
