Similarly to other adult tissues,a hierarchical structure has been established for the brain,where the differentiated cell types（neurons,oligodendrocytes and astrocytes）are generated from primary progenitor cells,kn...Similarly to other adult tissues,a hierarchical structure has been established for the brain,where the differentiated cell types（neurons,oligodendrocytes and astrocytes）are generated from primary progenitor cells,known as type B astrocytes or neural stem cells （NSC）, through one or multiple stages of amplification （transient amplifying cells） that generate precursor cells （iPC） with more restricted potential nlPCs （neural）, alPCs （astrocytes）, olPC （oligodendrocytes） （Kriegstein and Alvarez-Buvlla, 2009）.展开更多
文摘Similarly to other adult tissues,a hierarchical structure has been established for the brain,where the differentiated cell types（neurons,oligodendrocytes and astrocytes）are generated from primary progenitor cells,known as type B astrocytes or neural stem cells （NSC）, through one or multiple stages of amplification （transient amplifying cells） that generate precursor cells （iPC） with more restricted potential nlPCs （neural）, alPCs （astrocytes）, olPC （oligodendrocytes） （Kriegstein and Alvarez-Buvlla, 2009）.
