Autoimmune limbic encephalitis is most commonly associated with antibodies against the N‑methyl‑D‑aspartate receptor(NMDAR),among other neuronal cell surface receptors.Here,a case of a pregnant female with limbic ence...Autoimmune limbic encephalitis is most commonly associated with antibodies against the N‑methyl‑D‑aspartate receptor(NMDAR),among other neuronal cell surface receptors.Here,a case of a pregnant female with limbic encephalitis in the presence of multiple additional autoimmune antibodies is described.The patient was a 36‑year‑old female who presented with 4 days of confusion,hallucinations,hypersexuality,disinhibition,and pressured speech.The patient’s work‑up detected the presence of anti‑NMDAR antibodies,anti‑glutamic acid decarboxylase antibodies,and a yet uncharacterized neuronal autoantibody.The patient was also found to be pregnant.No evidence of ovarian or other pelvic malignancy was discovered.Symptomatic control was achieved with plasma exchange.展开更多
文摘Autoimmune limbic encephalitis is most commonly associated with antibodies against the N‑methyl‑D‑aspartate receptor(NMDAR),among other neuronal cell surface receptors.Here,a case of a pregnant female with limbic encephalitis in the presence of multiple additional autoimmune antibodies is described.The patient was a 36‑year‑old female who presented with 4 days of confusion,hallucinations,hypersexuality,disinhibition,and pressured speech.The patient’s work‑up detected the presence of anti‑NMDAR antibodies,anti‑glutamic acid decarboxylase antibodies,and a yet uncharacterized neuronal autoantibody.The patient was also found to be pregnant.No evidence of ovarian or other pelvic malignancy was discovered.Symptomatic control was achieved with plasma exchange.
