The physical accessibility of specific genomic regions is a chromatin property that regulates gene expression and allows the establishment of an appropriate transcriptional landscape in response to environmental and d...The physical accessibility of specific genomic regions is a chromatin property that regulates gene expression and allows the establishment of an appropriate transcriptional landscape in response to environmental and developmental signals.In eukaryotes,ATP-dependent chromatin remodeling complexes use the energy produced via ATP hydrolysis by an ATPase subunit to perform DNA translocation.These complexes are classified into four subfamilies,based on the domain organization of their catalytic ATPases(Clapier et al.,2017).展开更多
文摘The physical accessibility of specific genomic regions is a chromatin property that regulates gene expression and allows the establishment of an appropriate transcriptional landscape in response to environmental and developmental signals.In eukaryotes,ATP-dependent chromatin remodeling complexes use the energy produced via ATP hydrolysis by an ATPase subunit to perform DNA translocation.These complexes are classified into four subfamilies,based on the domain organization of their catalytic ATPases(Clapier et al.,2017).
