Objective: To provide guidance for future randomized controlled trials (RCTs) based on a review con- cerning acupuncture for treating polycystic ovary syndrome (PCOS). Methods: A comprehensive literature search ...Objective: To provide guidance for future randomized controlled trials (RCTs) based on a review con- cerning acupuncture for treating polycystic ovary syndrome (PCOS). Methods: A comprehensive literature search was conducted in October 2015 using MEDLINE, EMBASE, SCISEARCH, Cumulative Index to Nursing and Allied Health Literature, the Cochrane Menstrual Disorders and Subfertility Group trials register, Allied and Complementary Medi- cine (AMED), China National Knowledge Infrastructure (CNKI), and the Wanfang databases. RCTs comparing either acupuncture with no/sham/pharmacological intervention or a combination of acupuncture and conventional therapy with conventional therapy in the treatment of PCOS were included in this review. A quality evaluation was performed for each of the included studies. Results: Thirty-one RCTs were included in the review and were divided into four categories according to the type of intervention used in the comparator or control group. Menstrual frequency, hor- mones, anthropometrics, insulin sensitivity, blood lipids, and fertility were used as the main measurements to assess the effects of acupuncture on the patients with PCOS. Thirty trials, except for one, showed an improvement in at least one of the indicators of PCOS after acupuncture treatment. However, normalizing the methodological and reporting format remains an issue. Conclusions: Based upon this review of current clinical trials concerning acupuncture for treating PCOS, we provide guidelines for better clinical trial design in the future.展开更多
Tuberculosis is still one of the major causes of illness and death in developing countries.Tuberculous lymphadenitis is the most common form of extrapulmonary tuberculosis.Even in the developed countries,where the dis...Tuberculosis is still one of the major causes of illness and death in developing countries.Tuberculous lymphadenitis is the most common form of extrapulmonary tuberculosis.Even in the developed countries,where the disease has been controlled to a large extent,it is again posing a new health challenge due to HIV,migrants,and immunosuppressive therapy.展开更多
基金Project supported by the China Scholarship Council(No.2013083 30139)the Zhejiang Traditional Chinese Medicine Foundation(No.2015ZQ025)the Ministry of Health Special Fund of China(No.201302013)
文摘Objective: To provide guidance for future randomized controlled trials (RCTs) based on a review con- cerning acupuncture for treating polycystic ovary syndrome (PCOS). Methods: A comprehensive literature search was conducted in October 2015 using MEDLINE, EMBASE, SCISEARCH, Cumulative Index to Nursing and Allied Health Literature, the Cochrane Menstrual Disorders and Subfertility Group trials register, Allied and Complementary Medi- cine (AMED), China National Knowledge Infrastructure (CNKI), and the Wanfang databases. RCTs comparing either acupuncture with no/sham/pharmacological intervention or a combination of acupuncture and conventional therapy with conventional therapy in the treatment of PCOS were included in this review. A quality evaluation was performed for each of the included studies. Results: Thirty-one RCTs were included in the review and were divided into four categories according to the type of intervention used in the comparator or control group. Menstrual frequency, hor- mones, anthropometrics, insulin sensitivity, blood lipids, and fertility were used as the main measurements to assess the effects of acupuncture on the patients with PCOS. Thirty trials, except for one, showed an improvement in at least one of the indicators of PCOS after acupuncture treatment. However, normalizing the methodological and reporting format remains an issue. Conclusions: Based upon this review of current clinical trials concerning acupuncture for treating PCOS, we provide guidelines for better clinical trial design in the future.
文摘Tuberculosis is still one of the major causes of illness and death in developing countries.Tuberculous lymphadenitis is the most common form of extrapulmonary tuberculosis.Even in the developed countries,where the disease has been controlled to a large extent,it is again posing a new health challenge due to HIV,migrants,and immunosuppressive therapy.