Background:Breast cancer is more common among young women in China than in developed countries.This study analyzes the clinicopathological features and prognosis of young women with breast cancer in southwest China.Ma...Background:Breast cancer is more common among young women in China than in developed countries.This study analyzes the clinicopathological features and prognosis of young women with breast cancer in southwest China.Materials and Methods:We reviewed the records of 406 breast cancer patients≤35 years old from 2008 to 2017 in southwest China,investigating their biological characteristics and prognosis.Results:In southwest China,8.77%of breast cancer patients were young women.Although the number of breast cancer cases increased over time,the proportion of young women declined.Patients in stages III and IV accounted for 32%of cases.Young women with breast cancer often experienced local and regional recurrence and had a poor prognosis(5-year disease-free survival rate of 54.9%and 5-year overall survival rate of 71.3%).T and N stages were significantly related to disease-free survival and overall survival.Hormone receptor status was associated with overall survival.Conclusions:In southwest China,young women with breast cancer tend to present with late-stage clinical features,and the prognosis remains poor.展开更多
Our study is concerned with the time-varying formation tracking problem for second-order multi-agent systems that are subject to unknown nonlinear dynamics and external disturbance, and the states of the followers for...Our study is concerned with the time-varying formation tracking problem for second-order multi-agent systems that are subject to unknown nonlinear dynamics and external disturbance, and the states of the followers form a predefined time-varying formation while tracking the state of the leader. The total uncertainty lumps the unknown nonlinear dynamics and the external disturbance, and is regarded as an extended state of the agent. To estimate the total uncertainty, we design an extended state observer(ESO). Then we propose a novel ESO based time-varying formation tracking protocol. It is proved that, under the proposed protocol, the ESO estimation error and the time-varying formation tracking error can be made arbitrarily small. An application to the target enclosing problem for multiple unmanned aerial vehicles(UAVs) verifies the effectiveness and superiority of the proposed approach.展开更多
文摘Background:Breast cancer is more common among young women in China than in developed countries.This study analyzes the clinicopathological features and prognosis of young women with breast cancer in southwest China.Materials and Methods:We reviewed the records of 406 breast cancer patients≤35 years old from 2008 to 2017 in southwest China,investigating their biological characteristics and prognosis.Results:In southwest China,8.77%of breast cancer patients were young women.Although the number of breast cancer cases increased over time,the proportion of young women declined.Patients in stages III and IV accounted for 32%of cases.Young women with breast cancer often experienced local and regional recurrence and had a poor prognosis(5-year disease-free survival rate of 54.9%and 5-year overall survival rate of 71.3%).T and N stages were significantly related to disease-free survival and overall survival.Hormone receptor status was associated with overall survival.Conclusions:In southwest China,young women with breast cancer tend to present with late-stage clinical features,and the prognosis remains poor.
基金Project supported by the Delta-NTU Corporate Lab through the NRF Corporate Lab@University Scheme
文摘Our study is concerned with the time-varying formation tracking problem for second-order multi-agent systems that are subject to unknown nonlinear dynamics and external disturbance, and the states of the followers form a predefined time-varying formation while tracking the state of the leader. The total uncertainty lumps the unknown nonlinear dynamics and the external disturbance, and is regarded as an extended state of the agent. To estimate the total uncertainty, we design an extended state observer(ESO). Then we propose a novel ESO based time-varying formation tracking protocol. It is proved that, under the proposed protocol, the ESO estimation error and the time-varying formation tracking error can be made arbitrarily small. An application to the target enclosing problem for multiple unmanned aerial vehicles(UAVs) verifies the effectiveness and superiority of the proposed approach.
