Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colore...Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies.展开更多
It is known that phosphorus can refine the primary silicon and heat treatment can spheroidize the eutectic silicon. This paper presents an optimal combination of heat treatment processes and P refinement on hypereutec...It is known that phosphorus can refine the primary silicon and heat treatment can spheroidize the eutectic silicon. This paper presents an optimal combination of heat treatment processes and P refinement on hypereutectic AI-Si alloy. The optimal P addition amount, and the solution and aging temperatures for AI-25%Si alloy were obtained through the orthogonal experiment, and their modification effects were discussed. The results show that P addition has the greatest modification effect, followed by aging temperature, and the modification effect of solution temperature is the least. The optimized modification parameters are: addition of 0.6% P, solution at 540℃ and aging at 160℃. In addition, the cooling curve, superheating and hardness of the alloy were also analyzed.展开更多
A one-dimensional pipe flow model of single-cylinder diesel engine is established to investigate the intake and exhaust flow characteristics of diesel engine in the condition of high power density(HPD).A space-lime co...A one-dimensional pipe flow model of single-cylinder diesel engine is established to investigate the intake and exhaust flow characteristics of diesel engine in the condition of high power density(HPD).A space-lime conservation element and solution element(CE/SE)method is used to derive the discrete equations of the partial differential equation for the intake and exhaust systems.The performance parameters of diesel engine with speed of 2100 r/min are simulated.The simulated results are in accordance with the experimental data.The effect of increased power density on charging coefficient is analyzed using a validated model.The results show that the charging coefficient is slowly improved with the increase in intake pressure,and is obviously reduced with the increase in engine speed.展开更多
Fe-based metallic glasses of(Fe74Nb6B20)100?xCrx(x=1,3,5)with high glass forming ability(GFA)and good magneticproperties were prepared using low-purity raw materials.Increasing Cr content does not significantly change...Fe-based metallic glasses of(Fe74Nb6B20)100?xCrx(x=1,3,5)with high glass forming ability(GFA)and good magneticproperties were prepared using low-purity raw materials.Increasing Cr content does not significantly change glass transitiontemperature and onset crystallization temperature,while it enhances liquidus temperature.The addition of Cr improves the GFA ofthe(Fe74Nb6B20)100?xCrx glassy alloys compared to that in Cr-free Fe?Nb?B alloys,in which the supercooled liquid region(ΔTx),Trgandγare found to be50?54K,0.526?0.538,and0.367?0.371,respectively.The(Fe74Nb6B20)100?xCrx glassy alloys exhibit excellentsoft magnetic properties with high saturation magnetization of139?161A·m2/kg and low coercivity of30.24?58.9A/m.PresentFe?Nb?B?Cr glassy alloys exhibiting high GFA as well as excellent magnetic properties and low manufacturing cost make themsuitable for magnetic components for engineering application.展开更多
BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation be...BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation between the clinical efficacy of low-frequency electrical stimulation combined with tri-tongue acupuncture in patients with post-stroke dysarthria.AIM To investigate the clinical effects of tri-tongue acupuncture combined with lowfrequency electrical stimulation for treating post-stroke dysarthria.METHODS Ninety patients with post-stroke dysarthria,who were admitted to our hospital from December 2019 to June 2021,were selected and equally divided into two groups(n=45/group)according to the random number table method.Tri-tongue acupuncture was administered in the control group.The treatment group received both tri-tongue acupuncture and low-frequency electrical stimulation.The clinical efficacy,Western Aphasia Battery(WAB)score,general quality of life inventory(GQOLI-74)score,Frenchay Dysarthria Assessment score,and speech function grades were compared and analyzed between both groups.RESULTS The overall efficacy in the treatment group was better than that in the control group(P<0.05).Before treatment,the WAB,Frenchay Dysarthria Assessment,or GQOLI-74 scores(P>0.05)did not differ between the groups.After therapy,the WAB,Frenchay Dysarthria Assessment,and GQOLI-74 scores in both groups increased significantly(P<0.05),and the treatment group exhibited a significantly greater increase than that of the controls(P<0.05).Moreover,the classification of speech function did not differ between the two groups before treatment(P>0.05),whereas significant improvements were observed in both groups after treatment(P<0.05).The degree of improvement in the treatment group was greater than that in the control group(P<0.05).CONCLUSION Low-frequency electrical stimulation,in conjunction with tri-tongue acupuncture,exhibits a good clinical effect on post-stroke dysarthria.展开更多
There are generally four recognized classes of japonica rice cultivars grown in the lower region of the Yangtze River valley. The geographical distribution of the four classes is latitude-dependent. Variation for head...There are generally four recognized classes of japonica rice cultivars grown in the lower region of the Yangtze River valley. The geographical distribution of the four classes is latitude-dependent. Variation for heading date (HD) among 29 japonica rice cultivars grown in the lower region of the Yangtze River valley and belonging to the four classes was characterized, and their sensitivity to variations in photoperiod and temperature was analyzed. All of the cultivars were sensitive to both photoperiod and temperature. A regression analysis showed that HD is closely correlated with photoperiod sensitivity (PS). The PS of the four classes increased gradually from the medium maturing middle (MMM) types, through the late maturing middle (LMM) and early maturing late (EML) types to the medium maturing late (MML) types. Crosses with tester lines established that almost all of the cultivars carry the dominant early-heading allele at Ef-1, the photoperiod insensitive allele e2 and the PS alleles E1 or E1^t. Most of the MMM, LMM and MML types carry the insensitive allele e3, while EML types have either E3 or E3^t. At Se-1, MMM and LMM types have Se-1^e, some EML types have Se-1^e and others Se-1^n, while the MML types are mostly Se-fn. The PS of some MMM, LMM and EML types is reduced by the presence of hd2. These results show that the distribution of the four rice cultivar classes from high latitude to low latitude regions depended on a gradual increase in PS, which is mainly determined by its HD genotypes.展开更多
Middle indica cultivars are planted in the middle to lower regions of the Yangtze River. Hybrid combinations with these cultivars have a high yield potential but the presence of late-transgressive-segregants limits th...Middle indica cultivars are planted in the middle to lower regions of the Yangtze River. Hybrid combinations with these cultivars have a high yield potential but the presence of late-transgressive-segregants limits the further exploitation of heterosis. To understand the genetic basis of the heading date in these middle maturing cultivars, we carried out a genetic analysis of 10 typical middle-season cultivars using a number of heading date isogenic lines under both long and short day conditions. The results showed that Teqing, 752, CDR22, Bo B, 9311 and 11-32B carry two photoperiod sensitive genes E1 or Se.1 and E3, and Teqing, 752 and CDR22 carry a dominant early-heading gene Ef-1 while Bo B, 9311 and 11-32B carry a recessive late-heading gene ef-1. Based on the findings of the present and previous works on Guichao 2, Minghui 63, Nanjing 11 and Pei'ai64S, it was concluded that all of these middle indica cultivars carried the recessive allele hd2, which could inhibit the expression of El or Se.1, and they formed rational combinations of genotype for heading date during a long period of evolution. The effects of the different combinations of genotype for heading date on rice cultivation and extension were discussed, and genetic basis of broad adaptability of hybrid middle indica cultivars was analyzed.展开更多
Net primary productivity (NPP) is a key component of energy and matter transformation in the terrestrial ecosystem, and the responses of NPP to global change locally and regionally have been one of the most importan...Net primary productivity (NPP) is a key component of energy and matter transformation in the terrestrial ecosystem, and the responses of NPP to global change locally and regionally have been one of the most important aspects in climatevegetation relationship studies. In order to isolate causal climatic factors, it is very important to assess the response of seasonal variation of NPP to climate. In this paper, NPP in Xinjiang was estimated by NOAA/AVHRR Normalized Difference Vegetation Index (NDVI) data and geographic information system (GIS) techniques. The impact of climatic factors (air temperature, precipitation and sunshine percentage) on seasonal variations of NPP was studied by time lag and serial correlation ageing analysis. The results showed that the NPP for different land cover types have a similar correlation with any one of the three climatic factors, and precipitation is the major climatic factor influencing the seasonal variation of NPP in Xinjiang. It was found that the positive correlation at 0lag appeared between NPP and precipitation and the serial correlation ageing was 0 d in most areas of Xinjiang, which indicated that the response of NPP to precipitation was immediate. However, NPP of different land cover types showed significant positive correlation at 2 month lag with air temperature, and the impact of which could persist 1 month as a whole. No correlation was found between NPP and sunshine percentage.展开更多
II-32A, an elite male-sterile line of rice (Oryza sativa L.), has been widely used for the production of hybrid rice seed In China. Heading date In most combinations using II-32A shows transgressive Inheritance or s...II-32A, an elite male-sterile line of rice (Oryza sativa L.), has been widely used for the production of hybrid rice seed In China. Heading date In most combinations using II-32A shows transgressive Inheritance or similarity to the latter parent, but the genotype of II-32A with respect to major genes for heading time Is unknown. This limits the further exploitation of this sterile line In breeding and hybrid seed production. Using a number of major gene heading date Isogenlc lines and heading date QTL near-lsogenic lines, we genetically analyzed II-32B under both long- and short-day conditions. We show that II-32B carries two photoperlod-sensltlve genes, E1 and E3, a recessive late-heading gene, ef-l, and a photoperlod-sensltlve allele, Se-1^u. In addition we Identified In II- 32B a recessive Inhibitor for E1 or Se-1^n and other modified photoperlod-sensltlve genes. The heading-date constitution of II-32A was determined to be E1e2E3Se-1^uef-li-Se-1.展开更多
基金supported by the Beijing Municipal Science and Technology Commission(BMSTC,No.D171100002617001).
文摘Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies.
基金financially supported by the National Natural Science Foundation of China(Nos.51401156,51371133 and 51671151)the Science and Technology Program of Shaanxi Province(No.2016KJXX-87)
文摘It is known that phosphorus can refine the primary silicon and heat treatment can spheroidize the eutectic silicon. This paper presents an optimal combination of heat treatment processes and P refinement on hypereutectic AI-Si alloy. The optimal P addition amount, and the solution and aging temperatures for AI-25%Si alloy were obtained through the orthogonal experiment, and their modification effects were discussed. The results show that P addition has the greatest modification effect, followed by aging temperature, and the modification effect of solution temperature is the least. The optimized modification parameters are: addition of 0.6% P, solution at 540℃ and aging at 160℃. In addition, the cooling curve, superheating and hardness of the alloy were also analyzed.
文摘A one-dimensional pipe flow model of single-cylinder diesel engine is established to investigate the intake and exhaust flow characteristics of diesel engine in the condition of high power density(HPD).A space-lime conservation element and solution element(CE/SE)method is used to derive the discrete equations of the partial differential equation for the intake and exhaust systems.The performance parameters of diesel engine with speed of 2100 r/min are simulated.The simulated results are in accordance with the experimental data.The effect of increased power density on charging coefficient is analyzed using a validated model.The results show that the charging coefficient is slowly improved with the increase in intake pressure,and is obviously reduced with the increase in engine speed.
基金Projects(51301125,51171136,51502234,51401156,11404251)supported by the National Natural Science Foundation of ChinaProject(2013JK0907)supported by Scientific Research Program Funded by Shaanxi Provincial Education Department,China
文摘Fe-based metallic glasses of(Fe74Nb6B20)100?xCrx(x=1,3,5)with high glass forming ability(GFA)and good magneticproperties were prepared using low-purity raw materials.Increasing Cr content does not significantly change glass transitiontemperature and onset crystallization temperature,while it enhances liquidus temperature.The addition of Cr improves the GFA ofthe(Fe74Nb6B20)100?xCrx glassy alloys compared to that in Cr-free Fe?Nb?B alloys,in which the supercooled liquid region(ΔTx),Trgandγare found to be50?54K,0.526?0.538,and0.367?0.371,respectively.The(Fe74Nb6B20)100?xCrx glassy alloys exhibit excellentsoft magnetic properties with high saturation magnetization of139?161A·m2/kg and low coercivity of30.24?58.9A/m.PresentFe?Nb?B?Cr glassy alloys exhibiting high GFA as well as excellent magnetic properties and low manufacturing cost make themsuitable for magnetic components for engineering application.
文摘BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation between the clinical efficacy of low-frequency electrical stimulation combined with tri-tongue acupuncture in patients with post-stroke dysarthria.AIM To investigate the clinical effects of tri-tongue acupuncture combined with lowfrequency electrical stimulation for treating post-stroke dysarthria.METHODS Ninety patients with post-stroke dysarthria,who were admitted to our hospital from December 2019 to June 2021,were selected and equally divided into two groups(n=45/group)according to the random number table method.Tri-tongue acupuncture was administered in the control group.The treatment group received both tri-tongue acupuncture and low-frequency electrical stimulation.The clinical efficacy,Western Aphasia Battery(WAB)score,general quality of life inventory(GQOLI-74)score,Frenchay Dysarthria Assessment score,and speech function grades were compared and analyzed between both groups.RESULTS The overall efficacy in the treatment group was better than that in the control group(P<0.05).Before treatment,the WAB,Frenchay Dysarthria Assessment,or GQOLI-74 scores(P>0.05)did not differ between the groups.After therapy,the WAB,Frenchay Dysarthria Assessment,and GQOLI-74 scores in both groups increased significantly(P<0.05),and the treatment group exhibited a significantly greater increase than that of the controls(P<0.05).Moreover,the classification of speech function did not differ between the two groups before treatment(P>0.05),whereas significant improvements were observed in both groups after treatment(P<0.05).The degree of improvement in the treatment group was greater than that in the control group(P<0.05).CONCLUSION Low-frequency electrical stimulation,in conjunction with tri-tongue acupuncture,exhibits a good clinical effect on post-stroke dysarthria.
基金Supported by the National Hi-Tech Research and Development Programof China (2006AA100101,2006BAD01A01-5 and 2006BAD13B01)the National Natural Science Foundation of China (30871497)+2 种基金Jiangsu Scienceand Technology Development Program (BG2006301)Jiangsu Agricultural Germplasm Gene Pool Program (sx(2008)g08)the 111 Project (B08025)
文摘There are generally four recognized classes of japonica rice cultivars grown in the lower region of the Yangtze River valley. The geographical distribution of the four classes is latitude-dependent. Variation for heading date (HD) among 29 japonica rice cultivars grown in the lower region of the Yangtze River valley and belonging to the four classes was characterized, and their sensitivity to variations in photoperiod and temperature was analyzed. All of the cultivars were sensitive to both photoperiod and temperature. A regression analysis showed that HD is closely correlated with photoperiod sensitivity (PS). The PS of the four classes increased gradually from the medium maturing middle (MMM) types, through the late maturing middle (LMM) and early maturing late (EML) types to the medium maturing late (MML) types. Crosses with tester lines established that almost all of the cultivars carry the dominant early-heading allele at Ef-1, the photoperiod insensitive allele e2 and the PS alleles E1 or E1^t. Most of the MMM, LMM and MML types carry the insensitive allele e3, while EML types have either E3 or E3^t. At Se-1, MMM and LMM types have Se-1^e, some EML types have Se-1^e and others Se-1^n, while the MML types are mostly Se-fn. The PS of some MMM, LMM and EML types is reduced by the presence of hd2. These results show that the distribution of the four rice cultivar classes from high latitude to low latitude regions depended on a gradual increase in PS, which is mainly determined by its HD genotypes.
基金Supported by the High-Tech Research and Development(863) Program of Chinathe National Natural Science Foundation of China(30571142)the High Technology Program of Jiangsu Province(BG2004303 and BG2006301) and PCSIRT
文摘Middle indica cultivars are planted in the middle to lower regions of the Yangtze River. Hybrid combinations with these cultivars have a high yield potential but the presence of late-transgressive-segregants limits the further exploitation of heterosis. To understand the genetic basis of the heading date in these middle maturing cultivars, we carried out a genetic analysis of 10 typical middle-season cultivars using a number of heading date isogenic lines under both long and short day conditions. The results showed that Teqing, 752, CDR22, Bo B, 9311 and 11-32B carry two photoperiod sensitive genes E1 or Se.1 and E3, and Teqing, 752 and CDR22 carry a dominant early-heading gene Ef-1 while Bo B, 9311 and 11-32B carry a recessive late-heading gene ef-1. Based on the findings of the present and previous works on Guichao 2, Minghui 63, Nanjing 11 and Pei'ai64S, it was concluded that all of these middle indica cultivars carried the recessive allele hd2, which could inhibit the expression of El or Se.1, and they formed rational combinations of genotype for heading date during a long period of evolution. The effects of the different combinations of genotype for heading date on rice cultivation and extension were discussed, and genetic basis of broad adaptability of hybrid middle indica cultivars was analyzed.
基金Supported by the Hi-Tech Research and Development (863) Program of China (2006AA12010103)the China Meteorological Administration (CCSF2006-37)Xinjiang Meteorological Bureau (QSR2003010006).
文摘Net primary productivity (NPP) is a key component of energy and matter transformation in the terrestrial ecosystem, and the responses of NPP to global change locally and regionally have been one of the most important aspects in climatevegetation relationship studies. In order to isolate causal climatic factors, it is very important to assess the response of seasonal variation of NPP to climate. In this paper, NPP in Xinjiang was estimated by NOAA/AVHRR Normalized Difference Vegetation Index (NDVI) data and geographic information system (GIS) techniques. The impact of climatic factors (air temperature, precipitation and sunshine percentage) on seasonal variations of NPP was studied by time lag and serial correlation ageing analysis. The results showed that the NPP for different land cover types have a similar correlation with any one of the three climatic factors, and precipitation is the major climatic factor influencing the seasonal variation of NPP in Xinjiang. It was found that the positive correlation at 0lag appeared between NPP and precipitation and the serial correlation ageing was 0 d in most areas of Xinjiang, which indicated that the response of NPP to precipitation was immediate. However, NPP of different land cover types showed significant positive correlation at 2 month lag with air temperature, and the impact of which could persist 1 month as a whole. No correlation was found between NPP and sunshine percentage.
文摘II-32A, an elite male-sterile line of rice (Oryza sativa L.), has been widely used for the production of hybrid rice seed In China. Heading date In most combinations using II-32A shows transgressive Inheritance or similarity to the latter parent, but the genotype of II-32A with respect to major genes for heading time Is unknown. This limits the further exploitation of this sterile line In breeding and hybrid seed production. Using a number of major gene heading date Isogenlc lines and heading date QTL near-lsogenic lines, we genetically analyzed II-32B under both long- and short-day conditions. We show that II-32B carries two photoperlod-sensltlve genes, E1 and E3, a recessive late-heading gene, ef-l, and a photoperlod-sensltlve allele, Se-1^u. In addition we Identified In II- 32B a recessive Inhibitor for E1 or Se-1^n and other modified photoperlod-sensltlve genes. The heading-date constitution of II-32A was determined to be E1e2E3Se-1^uef-li-Se-1.