Dear Editor,The ongoing COVID-19 pandemic,caused by severe acute respiratory syndrome conronavirus 2(SARS-CoV-2),has led to over 209,201,939 confirmed cases and 4,390,467 deaths all over the world as of 19 August 2021...Dear Editor,The ongoing COVID-19 pandemic,caused by severe acute respiratory syndrome conronavirus 2(SARS-CoV-2),has led to over 209,201,939 confirmed cases and 4,390,467 deaths all over the world as of 19 August 2021(https://covid19.who.int/).Novel therapeutic agents and vaccines are desperately needed and mechanism exploration is imperative.Though clinical tissues are preferred samples for molecular and mechanism study,COVID-19 clinical tissues are rare and mostly come from autopsies of end-stage patients.1,2 Animal models,especially nonhuman primate models,are therefore constructed for SARS-CoV-2-associated research.展开更多
基金This study was supported by grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS2019-I2M-1-004,CIFMS2021-I2M-1-038,and CIFMS2021-I2M-1-016)National R&D Project of China(SQ2021YFC2300095+1 种基金2021YFC0863300)Yunnan Key R&D project(202103AC100001).
文摘Dear Editor,The ongoing COVID-19 pandemic,caused by severe acute respiratory syndrome conronavirus 2(SARS-CoV-2),has led to over 209,201,939 confirmed cases and 4,390,467 deaths all over the world as of 19 August 2021(https://covid19.who.int/).Novel therapeutic agents and vaccines are desperately needed and mechanism exploration is imperative.Though clinical tissues are preferred samples for molecular and mechanism study,COVID-19 clinical tissues are rare and mostly come from autopsies of end-stage patients.1,2 Animal models,especially nonhuman primate models,are therefore constructed for SARS-CoV-2-associated research.
