In a recent study published in Science Immunology,^Kusnadi et al.performed single-cell RNA sequencing(scRNA-seq)of SARS-CoV-2-reactive CD8^(+)T cells and reported heterogeneity.SARS-CoV-2 infection causes COVID-19,whi...In a recent study published in Science Immunology,^Kusnadi et al.performed single-cell RNA sequencing(scRNA-seq)of SARS-CoV-2-reactive CD8^(+)T cells and reported heterogeneity.SARS-CoV-2 infection causes COVID-19,which is an ongoing pandemic disease threatening public health.The virology of SARS-CoV-2 and immune responses against the virus have been urgently investigated to develop effective measures against COVID-19.During viral infection,CD84 T cells contribute to elimination of the virus by exerting cytotoxicity against virus-infected cells and producing effector cytokines,whereas neutralizing antibodies interfere with viral entry of host cells.展开更多
基金This research was supported by the 2020 Joint Research Project of Institutes of Science and Technology。
文摘In a recent study published in Science Immunology,^Kusnadi et al.performed single-cell RNA sequencing(scRNA-seq)of SARS-CoV-2-reactive CD8^(+)T cells and reported heterogeneity.SARS-CoV-2 infection causes COVID-19,which is an ongoing pandemic disease threatening public health.The virology of SARS-CoV-2 and immune responses against the virus have been urgently investigated to develop effective measures against COVID-19.During viral infection,CD84 T cells contribute to elimination of the virus by exerting cytotoxicity against virus-infected cells and producing effector cytokines,whereas neutralizing antibodies interfere with viral entry of host cells.
