In the version of this article initially published,unintended typographical errors in the original version of Fig.1B were made during manuscript preparation.The revised Fig.1,including the correct Fig.1B,isshown below.
CD8^(+)effector T(T_(E))cells play a critical role in immunity against infections.In response to a pathogenic stimulus,antigenpresenting cells(APCs)deliver three signals[via T-cell receptor(TCR),costimulation,and cyto...CD8^(+)effector T(T_(E))cells play a critical role in immunity against infections.In response to a pathogenic stimulus,antigenpresenting cells(APCs)deliver three signals[via T-cell receptor(TCR),costimulation,and cytokines]to naive CD8^(+)T cells,stimulating their entry into a developmental program characterized by T-cell expansion followed by a contraction phase.During the contraction phase,90-95%of IL-7R^(-)CD62L^(-)KLRG1^(+)T_(E)cells undergo cell apoptosis.展开更多
文摘In the version of this article initially published,unintended typographical errors in the original version of Fig.1B were made during manuscript preparation.The revised Fig.1,including the correct Fig.1B,isshown below.
基金This work was supported by a research grant(#PJT153314)from the Canadian Institute of Health Research(CIHR).
文摘CD8^(+)effector T(T_(E))cells play a critical role in immunity against infections.In response to a pathogenic stimulus,antigenpresenting cells(APCs)deliver three signals[via T-cell receptor(TCR),costimulation,and cytokines]to naive CD8^(+)T cells,stimulating their entry into a developmental program characterized by T-cell expansion followed by a contraction phase.During the contraction phase,90-95%of IL-7R^(-)CD62L^(-)KLRG1^(+)T_(E)cells undergo cell apoptosis.
