This study aimed to investigate the clinical characteristics of elderly-onset rheumatoid arthritis(EORA)patients with COVID-19.We ret-rospectively enrolled EORA patients diagnosed with COVID-19 from December 2022 thro...This study aimed to investigate the clinical characteristics of elderly-onset rheumatoid arthritis(EORA)patients with COVID-19.We ret-rospectively enrolled EORA patients diagnosed with COVID-19 from December 2022 through February 2023 and followed them up.Demographic characteristics of the patients and clinical data on COVID-19 were collected,and EORA-related data at the onset of rheu-matoid arthritis and during COVID-19 episodes were evaluated.A total of 102 EORA outpatients were enrolled and stratified into the COVID-19 group(n=60)and the non–COVID-19 group(n=42).In the COVID-19 group,56(93.3%)had symptoms,8(13.3%)had viral pneumonia,and 4(6.7%)developed severe COVID-19.Multivariate logistic regression analysis showed that lack of COVID-19 vac-cination(P=0.016 and P=0.030,respectively)and having interstitial lung disease(P=0.013 and P=0.001,respectively)were inde-pendent risk factors for viral pneumonia and severe COVID-19.Compared with the general population,EORA patients did not show significantly higher susceptibility to COVID-19 or a higher risk of severe COVID-19.However,EORA patients with interstitial lung disease require special consideration during COVID-19 episodes.展开更多
基金supported by the National Key Research and Development Program of China(2022YFC360200).
文摘This study aimed to investigate the clinical characteristics of elderly-onset rheumatoid arthritis(EORA)patients with COVID-19.We ret-rospectively enrolled EORA patients diagnosed with COVID-19 from December 2022 through February 2023 and followed them up.Demographic characteristics of the patients and clinical data on COVID-19 were collected,and EORA-related data at the onset of rheu-matoid arthritis and during COVID-19 episodes were evaluated.A total of 102 EORA outpatients were enrolled and stratified into the COVID-19 group(n=60)and the non–COVID-19 group(n=42).In the COVID-19 group,56(93.3%)had symptoms,8(13.3%)had viral pneumonia,and 4(6.7%)developed severe COVID-19.Multivariate logistic regression analysis showed that lack of COVID-19 vac-cination(P=0.016 and P=0.030,respectively)and having interstitial lung disease(P=0.013 and P=0.001,respectively)were inde-pendent risk factors for viral pneumonia and severe COVID-19.Compared with the general population,EORA patients did not show significantly higher susceptibility to COVID-19 or a higher risk of severe COVID-19.However,EORA patients with interstitial lung disease require special consideration during COVID-19 episodes.
