The authors report a patient with familial hemiplegic migraine type II who d eveloped a long- lasting attack including fever, right- sided hemiplegia, apha sia, and coma. Quantitative analysis of early gadolinium- enh...The authors report a patient with familial hemiplegic migraine type II who d eveloped a long- lasting attack including fever, right- sided hemiplegia, apha sia, and coma. Quantitative analysis of early gadolinium- enhanced MRI revealed a mild but significant left- hemispheric blood- brain barrier (BBB) opening l imited to the cortex and preceding cortical edema. The findings suggest that the delayed cortical edema was vasogenic in the severe migraine aura variant of thi s ATP1A2 mutation carrier.展开更多
文摘The authors report a patient with familial hemiplegic migraine type II who d eveloped a long- lasting attack including fever, right- sided hemiplegia, apha sia, and coma. Quantitative analysis of early gadolinium- enhanced MRI revealed a mild but significant left- hemispheric blood- brain barrier (BBB) opening l imited to the cortex and preceding cortical edema. The findings suggest that the delayed cortical edema was vasogenic in the severe migraine aura variant of thi s ATP1A2 mutation carrier.