Pemphigus is amucocutaneous intraepithelial blistering disease caused by autoantibodies to epithelial cell adhesion molecules (desmoglein). The association between pemphigus and malignant neoplasm is well recognized. ...Pemphigus is amucocutaneous intraepithelial blistering disease caused by autoantibodies to epithelial cell adhesion molecules (desmoglein). The association between pemphigus and malignant neoplasm is well recognized. We present the case of a 62-year-old woman with pemphigus vulgaris accompanied by multiple myeloma. To the best of our knowledge, this is the first report of a case of pemphigus v ulgaris concomitant with multiple myeloma. From the results of immunoblotting us ing normal human epidermal extracts and indirect immunofluorescence using rat bl adder sections,and her clinical manifestations, our case does not seem to be one of paraneoplastic pemphigus.展开更多
Two-proton relative momentum distributions from the break-up channels 23Al→p+p+21Na and 22Mg→p+p+20Ne at an energy of 60-70 A MeV have been measured together with two-proton opening angles at the projectile fragment...Two-proton relative momentum distributions from the break-up channels 23Al→p+p+21Na and 22Mg→p+p+20Ne at an energy of 60-70 A MeV have been measured together with two-proton opening angles at the projectile fragment separator beamline (RIPS) in the RIKEN Ring Cyclotron Facility. The results demonstrate the existence of diproton emission component from single-step 2He for highly excited 23Al and 22Mg.展开更多
文摘Pemphigus is amucocutaneous intraepithelial blistering disease caused by autoantibodies to epithelial cell adhesion molecules (desmoglein). The association between pemphigus and malignant neoplasm is well recognized. We present the case of a 62-year-old woman with pemphigus vulgaris accompanied by multiple myeloma. To the best of our knowledge, this is the first report of a case of pemphigus v ulgaris concomitant with multiple myeloma. From the results of immunoblotting us ing normal human epidermal extracts and indirect immunofluorescence using rat bl adder sections,and her clinical manifestations, our case does not seem to be one of paraneoplastic pemphigus.
基金supported by the National Natural Science Foundation of China (Grant Nos. 10775167, 10775168, 10979074, 10405032, 10747163, 10805067 and 10605036)the Major State Basic Research Development Program of China (Grant No. 2007CB815004)the Shanghai Development Foundation for Science and Technology (Grant No. 09JC1416800)
文摘Two-proton relative momentum distributions from the break-up channels 23Al→p+p+21Na and 22Mg→p+p+20Ne at an energy of 60-70 A MeV have been measured together with two-proton opening angles at the projectile fragment separator beamline (RIPS) in the RIKEN Ring Cyclotron Facility. The results demonstrate the existence of diproton emission component from single-step 2He for highly excited 23Al and 22Mg.