Objective: To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. Method: Two hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either...Objective: To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. Method: Two hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either a low dose protocol (1.5 μ M/min initially, increased by 1.5 μ M/min every 30 min) or a high dose protocol (4.5 μ M/min initially, increased by 4.5 μ m/min every 30 min) Results: High dose of oxytocin was associated with a significant shortening of labor 4 (1.10- 10) vs. 6 (1- 10) h, p< 0.0001 without a significant difference in cesarean delivery rate, neonatal and maternal outcome. Conclusion: The use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.展开更多
文摘Objective: To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. Method: Two hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either a low dose protocol (1.5 μ M/min initially, increased by 1.5 μ M/min every 30 min) or a high dose protocol (4.5 μ M/min initially, increased by 4.5 μ m/min every 30 min) Results: High dose of oxytocin was associated with a significant shortening of labor 4 (1.10- 10) vs. 6 (1- 10) h, p< 0.0001 without a significant difference in cesarean delivery rate, neonatal and maternal outcome. Conclusion: The use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.
