Objective:The objective of this study was to evaluate the effectiveness of flotation therapy combined with psychological resilience training in improving emotional regulation and sleep quality in patients recovering f...Objective:The objective of this study was to evaluate the effectiveness of flotation therapy combined with psychological resilience training in improving emotional regulation and sleep quality in patients recovering from viral infections and to assess the application of the traditional Chinese medicine(TCM)theory of“form and spirit co-nourishing”in modern healthcare interventions.Methods:A total of 20 patients recovering from viral infections with anxiety and sleep disturbances were randomly assigned to the experimental group(n=10)and the control group(n=10).The experimental group received a combination of resilience training,targeting five key areas:physiological regulation,cognitive restructuring,emotional management,self-efficacy,and social support,alongside flotation therapy,with 45-min weekly sessions.The control group received conventional medical treatment.Anxiety levels were measured using the Hamilton Anxiety Scale,while sleep quality was assessed using the Pittsburgh Sleep Quality Index,both before and after the intervention.Results:Compared with intervention before,the resilience level of the experimental group significantly increased after the intervention(P<0.001),while no notable changes were detected in the control group(P>0.05);the experimental group demonstrated significantly lower anxiety level and sleep disorder level and higher resilience level compared to the control group after the intervention(all P<0.001).Conclusion:The combined use of flotation therapy and resilience training,grounded in the TCM principle of“form and spirit co-nourishing,”significantly improves emotional regulation and sleep quality in patients recovering from viral infections.This integrative approach supports both physical and psychological healing,aligning with the TCM holistic treatment model,and offers a promising avenue for modern mental health interventions.展开更多
This paper analyzes the queuing problem that was experienced during the Shanghai World Expo of 2010. The queuing problem will be discussed at three levels. The three levels include the physical, psychological, and soc...This paper analyzes the queuing problem that was experienced during the Shanghai World Expo of 2010. The queuing problem will be discussed at three levels. The three levels include the physical, psychological, and social aspects of the queuing problem. The collective behavior of visitors is studied through analyzing the information from the different sources, such as, the network of electronic eyes, the evaluation platform based on mobile phone system and the Internet. A hybrid information network technology is implemented. Based on the Wuli-Shili-Renli (WSR) system methodology, a new theoretical analysis framework for the queuing problem is proposed.展开更多
Agile hardware development methodology has been widely adopted over the past decade.Despite the research progress,the industry still doubts its applicability,especially for the functional verification of complicated p...Agile hardware development methodology has been widely adopted over the past decade.Despite the research progress,the industry still doubts its applicability,especially for the functional verification of complicated processor chips.Functional verification commonly employs a simulation-based method of co-simulating the design under test with a reference model and checking the consistency of their outcomes given the same input stimuli.We observe limited collaboration and information exchange through the design and verification processes,dramatically leading to inefficiencies when applying the conventional functional verification workflow to agile development.In this paper,we propose workflow integration with collaborative task delegation and dynamic information exchange as the design principles to effectively address the challenges on functional verification under the agile development model.Based on workflow integration,we enhance the functional verification workflows with a series of novel methodologies and toolchains.The diff-rule based agile verification methodology(DRAV)reduces the overhead of building reference models with runtime execution information from designs under test.We present the RISC-V implementation for DRAV,DiffTest,which adopts information probes to extract internal design behaviors for co-simulation and debugging.It further integrates two plugins,namely XFUZZ for effective test generation guided by design coverage metrics and LightSSS for efficient fault analysis triggered by co-simulation mismatches.We present the integrated workflows for agile hardware development and demonstrate their effectiveness in designing and verifying RISC-V processors with 33 functional bugs found in NutShell.We also illustrate the efficiency of the proposed toolchains with a case study on a functional bug in the L2 cache of XiangShan.展开更多
This paper reported a wine-derived lactic acid bacterium,Lactiplantibacillus plantarum XJ25,which exhibited higher cell viability under acid stress upon methionine supplementation.Cellular morphology and the compositi...This paper reported a wine-derived lactic acid bacterium,Lactiplantibacillus plantarum XJ25,which exhibited higher cell viability under acid stress upon methionine supplementation.Cellular morphology and the composition of the cytomembrane phospholipids revealed a more solid membrane architecture presented in the acid-stressed cells treated with methionine supplementation.Transcriptional analysis showed L.plantarum XJ25 reduced methionine transport and homocysteine biosynthesis under acid stress.Subsequent overexpression assays proved that methio-nine supplementation could alleviate the cell toxicity from homocysteine accumulation under acid stress.Finally,L.plantarum XJ25 employed energy allocation strategy to response environmental changes by balancing the uptake methionine and adjusting saturated fatty acids(SFAs)in membrane.These data support a novel mechanism of acid resistance involving methionine utilization and cellular energy distribution in LAB and provide crucial theoretical clues for the mechanisms of acid resistance in other bacteria.展开更多
基金This study was sponsored by Major Project of Philosophy and Social Sciences in Zhejiang Province:Research on Public Risk Perception,Behavior Rules and Management Countermeasures under Major Public Health Emergencies(Fund Number:21XXCO4ZD).
文摘Objective:The objective of this study was to evaluate the effectiveness of flotation therapy combined with psychological resilience training in improving emotional regulation and sleep quality in patients recovering from viral infections and to assess the application of the traditional Chinese medicine(TCM)theory of“form and spirit co-nourishing”in modern healthcare interventions.Methods:A total of 20 patients recovering from viral infections with anxiety and sleep disturbances were randomly assigned to the experimental group(n=10)and the control group(n=10).The experimental group received a combination of resilience training,targeting five key areas:physiological regulation,cognitive restructuring,emotional management,self-efficacy,and social support,alongside flotation therapy,with 45-min weekly sessions.The control group received conventional medical treatment.Anxiety levels were measured using the Hamilton Anxiety Scale,while sleep quality was assessed using the Pittsburgh Sleep Quality Index,both before and after the intervention.Results:Compared with intervention before,the resilience level of the experimental group significantly increased after the intervention(P<0.001),while no notable changes were detected in the control group(P>0.05);the experimental group demonstrated significantly lower anxiety level and sleep disorder level and higher resilience level compared to the control group after the intervention(all P<0.001).Conclusion:The combined use of flotation therapy and resilience training,grounded in the TCM principle of“form and spirit co-nourishing,”significantly improves emotional regulation and sleep quality in patients recovering from viral infections.This integrative approach supports both physical and psychological healing,aligning with the TCM holistic treatment model,and offers a promising avenue for modern mental health interventions.
基金supported by the 973 Research program entitled "Studies on the perception and law of social collective behaviors under the hybrid information network",which was sponsored by the Ministry of Science and Technology of China
文摘This paper analyzes the queuing problem that was experienced during the Shanghai World Expo of 2010. The queuing problem will be discussed at three levels. The three levels include the physical, psychological, and social aspects of the queuing problem. The collective behavior of visitors is studied through analyzing the information from the different sources, such as, the network of electronic eyes, the evaluation platform based on mobile phone system and the Internet. A hybrid information network technology is implemented. Based on the Wuli-Shili-Renli (WSR) system methodology, a new theoretical analysis framework for the queuing problem is proposed.
基金supported in part by the Strategic Priority Research Program of Chinese Academy of Sciences(CAS)under Grant No.XDC05030200the National Key Research and Development Program of China under Grant No.2022YFB4500403+2 种基金the National Natural Science Foundation of China under Grant Nos.62090022 and 62172388the Youth Innovation Promotion Association of the Chinese Academy of Sciences under Grant No.2020105the Innovation Grant No.E261100 by Institute of Computing Technology,Chinese Academy of Sciences.
文摘Agile hardware development methodology has been widely adopted over the past decade.Despite the research progress,the industry still doubts its applicability,especially for the functional verification of complicated processor chips.Functional verification commonly employs a simulation-based method of co-simulating the design under test with a reference model and checking the consistency of their outcomes given the same input stimuli.We observe limited collaboration and information exchange through the design and verification processes,dramatically leading to inefficiencies when applying the conventional functional verification workflow to agile development.In this paper,we propose workflow integration with collaborative task delegation and dynamic information exchange as the design principles to effectively address the challenges on functional verification under the agile development model.Based on workflow integration,we enhance the functional verification workflows with a series of novel methodologies and toolchains.The diff-rule based agile verification methodology(DRAV)reduces the overhead of building reference models with runtime execution information from designs under test.We present the RISC-V implementation for DRAV,DiffTest,which adopts information probes to extract internal design behaviors for co-simulation and debugging.It further integrates two plugins,namely XFUZZ for effective test generation guided by design coverage metrics and LightSSS for efficient fault analysis triggered by co-simulation mismatches.We present the integrated workflows for agile hardware development and demonstrate their effectiveness in designing and verifying RISC-V processors with 33 functional bugs found in NutShell.We also illustrate the efficiency of the proposed toolchains with a case study on a functional bug in the L2 cache of XiangShan.
基金supported by the National Natural Science Foundation of China(32072206)the National Key R&D Program of China(2019YFD1002503)the China Technology Agriculture Research System(CARS-29-jg-3).
文摘This paper reported a wine-derived lactic acid bacterium,Lactiplantibacillus plantarum XJ25,which exhibited higher cell viability under acid stress upon methionine supplementation.Cellular morphology and the composition of the cytomembrane phospholipids revealed a more solid membrane architecture presented in the acid-stressed cells treated with methionine supplementation.Transcriptional analysis showed L.plantarum XJ25 reduced methionine transport and homocysteine biosynthesis under acid stress.Subsequent overexpression assays proved that methio-nine supplementation could alleviate the cell toxicity from homocysteine accumulation under acid stress.Finally,L.plantarum XJ25 employed energy allocation strategy to response environmental changes by balancing the uptake methionine and adjusting saturated fatty acids(SFAs)in membrane.These data support a novel mechanism of acid resistance involving methionine utilization and cellular energy distribution in LAB and provide crucial theoretical clues for the mechanisms of acid resistance in other bacteria.