Objective: The present study was designed to investigate the outcome of pregnancy and delivery in patients with anemia. Methods: A retrospective population-based study comparing all singleton pregnancies of patients w...Objective: The present study was designed to investigate the outcome of pregnancy and delivery in patients with anemia. Methods: A retrospective population-based study comparing all singleton pregnancies of patients with and without anemia was performed. Deliveries occurred during the years 1988-2002 in the Soroka University Medical Center. Maternal anemia was defined as hemoglobin concentration lower than 10 g/dl during pregnancy. Patients with hemoglobinopathies such as thalassemia were excluded from the analysis. Multiple logistic regression models were performed to control for confounders. Results: During the study period there were 153,396 deliveries, of which 13,204 (8.6%) occurred in patients with anemia. In a multivariable analysis, the following conditions were significantly associated with maternal anemia: placental abruption, placenta previa, labor induction, previous cesarean section (CS), non-vertex presentation and Bedouin ethnicity. Higher rates of preterm deliveries (< 37 weeks gestation) and low birthweight (< 2500 g) were found among patients with anemia as compared to the non-anemic women (10.7%versus 9.0%, p < 0.001 and 10.5%versus 9.4%, p < 0.001; respectively). Higher rates of CS were found among anemic women (20.4%versus 10.3%; p < 0.001). The significant association between anemia and low birthweight persisted after adjusting for gender, ethnicity and gestational age, using a multivariable analysis (OR = 1.1; 95%CI 1.0-1.2, p = 0.02). Two multivariable logistic regression models, with preterm delivery (< 37 weeks gestation) and low birthweight (< 2500 g) as the outcome variables, were constructed in order to control for possible confounders such as ethnicity, maternal age, placental problems, mode of delivery and non-vertex presentation. Maternal anemia was an independent risk factor for both, preterm delivery (OR = 1.2; 95%CI 1.1-1.2, p < 0.001) and low birthweight (OR = 1.1; 95%CI 1.1-1.2, p = 0.001). Conclusion: Maternal anemia influences birthweight and preterm delivery, but in our population, is not associated with adverse perinatal outcome.展开更多
This study was undertaken to determi ne uterine and fetal heart rate(FHR)tracing patterns associated with clinically apparent uterine leiomyomas.Uterine and FHR patterns of44women with diagnosed uterine leio myomas we...This study was undertaken to determi ne uterine and fetal heart rate(FHR)tracing patterns associated with clinically apparent uterine leiomyomas.Uterine and FHR patterns of44women with diagnosed uterine leio myomas were com-pared with 601tracings of controls.Tracings were inter-preted during the first stage of labor,using the National Institute of Child Health and Human Development Research Planning Workshop guidelines.Stra tified analysis that used the Mantel -Haenszel technique was p erformed to control for confounders.Patients with leio myomas had higher rates of uterine tachysystole as compared with those without leiomyomas(22.7%vs 1.3%;odds ratioOR=21.8,95%CI 7.4-65.6;P <.001).No significant differ-ences were noted between the groups r egarding FHR pat-terns.Higher rates’of prostaglandin induction and oxytocin augmentation were noted in the uterine leiomyomas group(6.8%vs 0.8%;P =.005and 52.3%vs 10.5%;P<.001,respectively).However,controlling for prostag-landin induction and oxytocin augme ntation,with the use of the Mantel -Haenszel procedure,did not change the sig-nificant association between uterine leiomyomas and tachysystole(weighted OR 12.5,95%CI 6.2-75.1,an d weighted OR 8.7,95%CI 3.6-43.1,respectively).Clinically apparent uterine leiomy omas,although not cou-pled with abnormal FHR patterns,are associated with higher rates of tachysystole.展开更多
文摘Objective: The present study was designed to investigate the outcome of pregnancy and delivery in patients with anemia. Methods: A retrospective population-based study comparing all singleton pregnancies of patients with and without anemia was performed. Deliveries occurred during the years 1988-2002 in the Soroka University Medical Center. Maternal anemia was defined as hemoglobin concentration lower than 10 g/dl during pregnancy. Patients with hemoglobinopathies such as thalassemia were excluded from the analysis. Multiple logistic regression models were performed to control for confounders. Results: During the study period there were 153,396 deliveries, of which 13,204 (8.6%) occurred in patients with anemia. In a multivariable analysis, the following conditions were significantly associated with maternal anemia: placental abruption, placenta previa, labor induction, previous cesarean section (CS), non-vertex presentation and Bedouin ethnicity. Higher rates of preterm deliveries (< 37 weeks gestation) and low birthweight (< 2500 g) were found among patients with anemia as compared to the non-anemic women (10.7%versus 9.0%, p < 0.001 and 10.5%versus 9.4%, p < 0.001; respectively). Higher rates of CS were found among anemic women (20.4%versus 10.3%; p < 0.001). The significant association between anemia and low birthweight persisted after adjusting for gender, ethnicity and gestational age, using a multivariable analysis (OR = 1.1; 95%CI 1.0-1.2, p = 0.02). Two multivariable logistic regression models, with preterm delivery (< 37 weeks gestation) and low birthweight (< 2500 g) as the outcome variables, were constructed in order to control for possible confounders such as ethnicity, maternal age, placental problems, mode of delivery and non-vertex presentation. Maternal anemia was an independent risk factor for both, preterm delivery (OR = 1.2; 95%CI 1.1-1.2, p < 0.001) and low birthweight (OR = 1.1; 95%CI 1.1-1.2, p = 0.001). Conclusion: Maternal anemia influences birthweight and preterm delivery, but in our population, is not associated with adverse perinatal outcome.
文摘This study was undertaken to determi ne uterine and fetal heart rate(FHR)tracing patterns associated with clinically apparent uterine leiomyomas.Uterine and FHR patterns of44women with diagnosed uterine leio myomas were com-pared with 601tracings of controls.Tracings were inter-preted during the first stage of labor,using the National Institute of Child Health and Human Development Research Planning Workshop guidelines.Stra tified analysis that used the Mantel -Haenszel technique was p erformed to control for confounders.Patients with leio myomas had higher rates of uterine tachysystole as compared with those without leiomyomas(22.7%vs 1.3%;odds ratioOR=21.8,95%CI 7.4-65.6;P <.001).No significant differ-ences were noted between the groups r egarding FHR pat-terns.Higher rates’of prostaglandin induction and oxytocin augmentation were noted in the uterine leiomyomas group(6.8%vs 0.8%;P =.005and 52.3%vs 10.5%;P<.001,respectively).However,controlling for prostag-landin induction and oxytocin augme ntation,with the use of the Mantel -Haenszel procedure,did not change the sig-nificant association between uterine leiomyomas and tachysystole(weighted OR 12.5,95%CI 6.2-75.1,an d weighted OR 8.7,95%CI 3.6-43.1,respectively).Clinically apparent uterine leiomy omas,although not cou-pled with abnormal FHR patterns,are associated with higher rates of tachysystole.
