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Clinical impact of minimal cancer cell detection in various colorectal cancer specimens 被引量:1
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作者 kazuhiko yoshimatsu Hajime Yokomizo Yoshihiko Naritaka 《World Journal of Gastroenterology》 SCIE CAS 2014年第35期12458-12461,共4页
Detection of cancer cells using molecular targets is achieved by combining immunochemical reactions with gene amplification techniques.This enables the detection of cancer cells in specimens that are traditionally det... Detection of cancer cells using molecular targets is achieved by combining immunochemical reactions with gene amplification techniques.This enables the detection of cancer cells in specimens that are traditionally determined to be cancer-free.These improvements in detection can lead to prognoses that are different from those derived by conventional pathological staging.Survival is worse when cancer cells are detected in regional lymph nodes compared to when the nodes are cancer-free.Furthermore,the circulating tumor cell(CTC) count increases as the cancer progresses.Consequently,there is a correlation between CTC count and prognosis.However,large-scale prospective studies are required to confirm this.The development of more convenient and cost-effective analysis techniques will facilitate the practical application of these findings. 展开更多
关键词 MICROMETASTASIS CIRCULATING tumor cell COLORECTAL
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