Hypotheses:Values of serum markers related to bone quality are abnormal in young female ballet dancers. Methods: In 13 elite Japanese female ballet dancers (average age, 22 years), markers related to bone quality were...Hypotheses:Values of serum markers related to bone quality are abnormal in young female ballet dancers. Methods: In 13 elite Japanese female ballet dancers (average age, 22 years), markers related to bone quality were investigated. These included: serum homocystein (HC), a marker of increased oxidative stress;pentosidine (Pent), a marker of glycation- or oxidation-induced non-enzymatic cross-links;markers of bone metabolism (bone alkaline phosphatase, BAP;tartrate-resistant acid phosphatase 5b, TRAP5b) and bone mineral density (BMD). It was determined whether there is a relationship between bone quality markers’ levels are related to amenorrhea and/or fatigue fractures. Results: Two dancers had fatigue fractures and 3 had a history of secondary amenorrhea. The average BMD was 1.305 ± 0.12 (g/cm2), in all these cases the Z-score was higher than -1.0. Although the serum levels of BAP, TRAP5b, and HC were normal in all examined dancers, in 2 out of 3 dancers with a history of secondary amenorrhea, pentosidine serum levels were increased. No relationship between bone quality markers’ levels and fatigue fractures was found. Conclusion: Latent deterioration of bone quality may occur in female athletes with secondary amenorrhea and otherwise normal BMD and calcium metabolism markers.展开更多
Since myasthenia gravis affects the muscular system, athletes suffering from the disease often have difficulty in performing or returning to their sports activity, in which exertion of continuous muscular power is req...Since myasthenia gravis affects the muscular system, athletes suffering from the disease often have difficulty in performing or returning to their sports activity, in which exertion of continuous muscular power is required. In this paper, we present a case of a professional bicycle rider with symptomatic MG who successfully return to his sport activity after thymectomy, steroid pulse therapy and aggressive rehabilitation. He resumed load training, returned to competitive cycling 8 months after leaving hospital while being on 20 mg PSL/day, and won seven victories in the top class cycling competitions. This is the first report on a professional athlete suffering from MG who successfully returned to competitive sports after aggressive steroid treatment.展开更多
文摘Hypotheses:Values of serum markers related to bone quality are abnormal in young female ballet dancers. Methods: In 13 elite Japanese female ballet dancers (average age, 22 years), markers related to bone quality were investigated. These included: serum homocystein (HC), a marker of increased oxidative stress;pentosidine (Pent), a marker of glycation- or oxidation-induced non-enzymatic cross-links;markers of bone metabolism (bone alkaline phosphatase, BAP;tartrate-resistant acid phosphatase 5b, TRAP5b) and bone mineral density (BMD). It was determined whether there is a relationship between bone quality markers’ levels are related to amenorrhea and/or fatigue fractures. Results: Two dancers had fatigue fractures and 3 had a history of secondary amenorrhea. The average BMD was 1.305 ± 0.12 (g/cm2), in all these cases the Z-score was higher than -1.0. Although the serum levels of BAP, TRAP5b, and HC were normal in all examined dancers, in 2 out of 3 dancers with a history of secondary amenorrhea, pentosidine serum levels were increased. No relationship between bone quality markers’ levels and fatigue fractures was found. Conclusion: Latent deterioration of bone quality may occur in female athletes with secondary amenorrhea and otherwise normal BMD and calcium metabolism markers.
文摘Since myasthenia gravis affects the muscular system, athletes suffering from the disease often have difficulty in performing or returning to their sports activity, in which exertion of continuous muscular power is required. In this paper, we present a case of a professional bicycle rider with symptomatic MG who successfully return to his sport activity after thymectomy, steroid pulse therapy and aggressive rehabilitation. He resumed load training, returned to competitive cycling 8 months after leaving hospital while being on 20 mg PSL/day, and won seven victories in the top class cycling competitions. This is the first report on a professional athlete suffering from MG who successfully returned to competitive sports after aggressive steroid treatment.
