<span style="font-family:Verdana;">Arylthiols were reacted with acrylonitrile under basic conditions to form the corresponding aryl</span><span style="font-family:""> </sp...<span style="font-family:Verdana;">Arylthiols were reacted with acrylonitrile under basic conditions to form the corresponding aryl</span><span style="font-family:""> </span><span style="font-family:Verdana;">sulfides which were oxidised with sodium metaperiodate in aqueous methanol to yield 3-arylsulphinylpropanenitriles that upon thermolysis in refluxing toluene produced a mixture of diarylthiosulfonates and diaryldisulfides. The mixture of </span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">two products w</span><span style="font-family:Verdana;">as</span><span style="font-family:""><span style="font-family:Verdana;"> easily separated by flash </span><span style="font-family:Verdana;">chromatography and characterized spectroscopically. The diarylthiosulfo</span><span style="font-family:Verdana;">nates </span><span style="font-family:Verdana;">and diaryldisulfides, garlic-like organosulfur compounds, were tested for</span><span style="font-family:Verdana;"> their antimicrobial properties against </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Pseudomonas aeruginosa</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Staphylococcus</span></i> <i><span style="font-family:Verdana;">aureus</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Helicobacter pylori </span></i><span style="font-family:Verdana;">and had been found to have good activity against </span><i><span style="font-family:Verdana;">S. aureas</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> with no activity against the other two organisms.</span></span>展开更多
文摘<span style="font-family:Verdana;">Arylthiols were reacted with acrylonitrile under basic conditions to form the corresponding aryl</span><span style="font-family:""> </span><span style="font-family:Verdana;">sulfides which were oxidised with sodium metaperiodate in aqueous methanol to yield 3-arylsulphinylpropanenitriles that upon thermolysis in refluxing toluene produced a mixture of diarylthiosulfonates and diaryldisulfides. The mixture of </span><span style="font-family:Verdana;">the </span><span style="font-family:Verdana;">two products w</span><span style="font-family:Verdana;">as</span><span style="font-family:""><span style="font-family:Verdana;"> easily separated by flash </span><span style="font-family:Verdana;">chromatography and characterized spectroscopically. The diarylthiosulfo</span><span style="font-family:Verdana;">nates </span><span style="font-family:Verdana;">and diaryldisulfides, garlic-like organosulfur compounds, were tested for</span><span style="font-family:Verdana;"> their antimicrobial properties against </span><i><span style="font-family:Verdana;">Escherichia coli</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Pseudomonas aeruginosa</span></i><span style="font-family:Verdana;">, </span><i><span style="font-family:Verdana;">Staphylococcus</span></i> <i><span style="font-family:Verdana;">aureus</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Helicobacter pylori </span></i><span style="font-family:Verdana;">and had been found to have good activity against </span><i><span style="font-family:Verdana;">S. aureas</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">H. pylori</span></i><span style="font-family:Verdana;"> with no activity against the other two organisms.</span></span>