Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old ...Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old female presented with abdominal bloating and increased abdominal girth. She underwent a supracervical hysterectomy, bilateral salpingo-oophorectomy, and omentectomy fora large pelvic mass. Immunophenotyping/flow cytometry revealed monoclonal B-cells positive for the CD 20 marker, consistent with NHL. A 47- year- old female presented with persistent vaginal discharge and an ulcerative lesion of the cervix. Cervical biopsies were non-diagnostic for carcinoma but immunophenotyping demonstrated CD 20 positive B- cells, consistent with NHL. Conclusion. Although uncommon, lymphoma should be included in the differential diagnosis of gynecologic malignancies because of a favorable outcome when properly diagnosed and treated.展开更多
BACKGROUND: Massive obstetric hemorrhage can be catastrophic, with considerable maternal morbidity and mortality. CASE: A 41-year-old term gravida experienced massive postpartum hemorrhage attributed to an amniotic fl...BACKGROUND: Massive obstetric hemorrhage can be catastrophic, with considerable maternal morbidity and mortality. CASE: A 41-year-old term gravida experienced massive postpartum hemorrhage attributed to an amniotic fluid embolism with rapid development of disseminated intravascular coagulation and resultant abdominal compartment syndrome. In this critically ill patient, a fascial prosthesis used for abdominal wall closure was placed to expedite multiple abdominal explorations and packing. Additionally, this device facilitated fascial closure once the abdominal compartment syndrome was resolved. CONCLUSION: Abdominal compartment syndrome resulting from overwhelming obstetric hemorrhagemay necessitate emergent decompressive laparotomy to alleviate increased intra-abdominal pressure and end-organ dysfunction. The fascial prosthesis allows a staged abdominal wall closure to be performed once the abdominal compartment syndrome is resolved.展开更多
文摘Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old female presented with abdominal bloating and increased abdominal girth. She underwent a supracervical hysterectomy, bilateral salpingo-oophorectomy, and omentectomy fora large pelvic mass. Immunophenotyping/flow cytometry revealed monoclonal B-cells positive for the CD 20 marker, consistent with NHL. A 47- year- old female presented with persistent vaginal discharge and an ulcerative lesion of the cervix. Cervical biopsies were non-diagnostic for carcinoma but immunophenotyping demonstrated CD 20 positive B- cells, consistent with NHL. Conclusion. Although uncommon, lymphoma should be included in the differential diagnosis of gynecologic malignancies because of a favorable outcome when properly diagnosed and treated.
文摘BACKGROUND: Massive obstetric hemorrhage can be catastrophic, with considerable maternal morbidity and mortality. CASE: A 41-year-old term gravida experienced massive postpartum hemorrhage attributed to an amniotic fluid embolism with rapid development of disseminated intravascular coagulation and resultant abdominal compartment syndrome. In this critically ill patient, a fascial prosthesis used for abdominal wall closure was placed to expedite multiple abdominal explorations and packing. Additionally, this device facilitated fascial closure once the abdominal compartment syndrome was resolved. CONCLUSION: Abdominal compartment syndrome resulting from overwhelming obstetric hemorrhagemay necessitate emergent decompressive laparotomy to alleviate increased intra-abdominal pressure and end-organ dysfunction. The fascial prosthesis allows a staged abdominal wall closure to be performed once the abdominal compartment syndrome is resolved.
