期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Preliminary Clinical Study Using a Novel Wound Dressing Composed of Hyaluronic Acid and Collagen Containing EGF 被引量:2
1
作者 Akane Yu Akira Takeda +6 位作者 kenichi kumazawa Hiroshi Miyoshi Misato Kuroyanagi Toshihiro Yoshitake Eiju Uchinuma Ryusuke Suzuki Yoshimitsu Kuroyanagi 《Open Journal of Regenerative Medicine》 2015年第1期6-13,共8页
This clinical trial aimed to evaluate the efficacy and safety of a novel wound dressing composed of hyaluronic acid (HA) and collagen (Col) containing epidermal growth factor (EGF), referred to as EGF-wound dressing. ... This clinical trial aimed to evaluate the efficacy and safety of a novel wound dressing composed of hyaluronic acid (HA) and collagen (Col) containing epidermal growth factor (EGF), referred to as EGF-wound dressing. EGF-wound dressing was prepared by freeze-drying a mixed aqueous solution of high-molecular-weight HA, low-molecular-weight HA and heat-denatured Col containing EGF. EGF-wound dressing was applied to skin defects, such as intractable skin ulcers, burn ulcers, traumatic skin defects and skin donor-site wounds. The dressing was changed twice a week for a period of 6 weeks or longer, if necessary. The primary endpoints were size of wound area, formation of granulation tissue, extent of epithelialization, infection control and macroscopic appearance. Effectiveness, safety and overall clinical evaluation were scored by plastic surgeons, as authorized by the Japanese Society of Plastic and Reconstructive Surgery. This study was registered with the University Hospital Medical Information Network (UMIN0000005264). Healthy granulation tissue and rapid epithelialization were observed for a given period after application of EGF-wound dressing onto the wounds. Most cases were assessed as having achieved good or excellent results. This clinical study demonstrated that EGF-wound dressing was beneficial in the treatment of various skin defects. 展开更多
关键词 Hyaluronic ACID COLLAGEN EPIDERMAL Growth Factor WOUND DRESSING
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部