BACKGROUND:Although invasive ductal adenocarcinoma of the pancreas(PDAC) manifests as a relatively uniform histomorphological feature of the pancreatobiliary type,it may be complicated by metaplastic changes and heter...BACKGROUND:Although invasive ductal adenocarcinoma of the pancreas(PDAC) manifests as a relatively uniform histomorphological feature of the pancreatobiliary type,it may be complicated by metaplastic changes and heterogeneous gastric and intestinal elements.This study aimed to investigate the complication rate and clinicopathological significance of such heterogeneous elements.METHODS:Fifty-nine patients who underwent resection of PDAC were examined in this study.Immunohistochemically,tumors showing high expression(>25%) of the intestinal-type(INT) marker CDX2 were classified as PDAC with INT.Those with high expression(>25%) of the gastric-type(GAS) marker MUC5AC were classified as PDAC with GAS,while those with high expression of both markers were classified as PDAC with INT/GAS.These patients were compared with those with PDAC of the negative group in which neither markers was highly expressed to examine their clinicopathological significance.RESULTS:In the 59 patients,31(52.5%) showed high CDX2 or MUC5AC expression.Twenty-eight patients(47.5%) belonged to a negative group,11(18.6%) to a PDAC with INT group,15(25.4%) to a PDAC with GAS group,and 5(8.5%) to a PDAC with INT/GAS group.No significant differences were observed for age,gender,size,localization,T classification,or prognosis among the four groups.Although the PDAC with GAS group had well differentiated types significantly more than the other groups,the rate of lymph node metastasis in this group was significantly higher(PDAC with GAS:73%;other groups:36%).CONCLUSION:Complications with heterogeneous elements are not uncommon in PDAC,and this should be considered during the diagnosis and treatment of PDAC along with histogenesis of the disease.展开更多
Visual cryptography is a method of encrypting an image into several encrypted images. Conventional visual cryptography can display only monochrome images. We previously proposed a color visual cryptography method that...Visual cryptography is a method of encrypting an image into several encrypted images. Conventional visual cryptography can display only monochrome images. We previously proposed a color visual cryptography method that uses the interference color of high-order retarder films and encrypts one secret image into two encrypted images. In other words, this method can only encrypt one image at a time. In this paper, we propose a new method that encrypts two color images using interference color.展开更多
Visual cryptography is an encryption method that shares a secret image through several encrypted images. General visual cryptography has no stacking order dependence, and only one image can be decoded regardless of st...Visual cryptography is an encryption method that shares a secret image through several encrypted images. General visual cryptography has no stacking order dependence, and only one image can be decoded regardless of stacking order of encrypted images. We previously reported a color visual cryptography using interference color (or polarization color) of retarder films. The interference color changes depending on the stacking order of retarder films. In this paper, we propose and develop a color visual cryptography that displays two images by changing stacking order of retarder films.展开更多
文摘BACKGROUND:Although invasive ductal adenocarcinoma of the pancreas(PDAC) manifests as a relatively uniform histomorphological feature of the pancreatobiliary type,it may be complicated by metaplastic changes and heterogeneous gastric and intestinal elements.This study aimed to investigate the complication rate and clinicopathological significance of such heterogeneous elements.METHODS:Fifty-nine patients who underwent resection of PDAC were examined in this study.Immunohistochemically,tumors showing high expression(>25%) of the intestinal-type(INT) marker CDX2 were classified as PDAC with INT.Those with high expression(>25%) of the gastric-type(GAS) marker MUC5AC were classified as PDAC with GAS,while those with high expression of both markers were classified as PDAC with INT/GAS.These patients were compared with those with PDAC of the negative group in which neither markers was highly expressed to examine their clinicopathological significance.RESULTS:In the 59 patients,31(52.5%) showed high CDX2 or MUC5AC expression.Twenty-eight patients(47.5%) belonged to a negative group,11(18.6%) to a PDAC with INT group,15(25.4%) to a PDAC with GAS group,and 5(8.5%) to a PDAC with INT/GAS group.No significant differences were observed for age,gender,size,localization,T classification,or prognosis among the four groups.Although the PDAC with GAS group had well differentiated types significantly more than the other groups,the rate of lymph node metastasis in this group was significantly higher(PDAC with GAS:73%;other groups:36%).CONCLUSION:Complications with heterogeneous elements are not uncommon in PDAC,and this should be considered during the diagnosis and treatment of PDAC along with histogenesis of the disease.
文摘Visual cryptography is a method of encrypting an image into several encrypted images. Conventional visual cryptography can display only monochrome images. We previously proposed a color visual cryptography method that uses the interference color of high-order retarder films and encrypts one secret image into two encrypted images. In other words, this method can only encrypt one image at a time. In this paper, we propose a new method that encrypts two color images using interference color.
文摘Visual cryptography is an encryption method that shares a secret image through several encrypted images. General visual cryptography has no stacking order dependence, and only one image can be decoded regardless of stacking order of encrypted images. We previously reported a color visual cryptography using interference color (or polarization color) of retarder films. The interference color changes depending on the stacking order of retarder films. In this paper, we propose and develop a color visual cryptography that displays two images by changing stacking order of retarder films.